Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tomoko Inubushi"'
Autor:
Naoko Ogawa, Tomoko Inubushi
Publikováno v:
Journal for the Integrated Study of Dietary Habits. 32:197-205
Autor:
Norio Kamemura, Bekki Yusuke, Mayumi Sugimoto, Shin Abe, Masamichi Ae, Tomoko Inubushi, Naohiro Imura
Publikováno v:
Drug and Chemical Toxicology. 42:430-435
Biphenyl is found both in natural and anthropogenic sources and is used as a fungistat in the packaging of citrus fruits. Acute exposure to high levels of biphenyl has been observed to cause skin irritation and toxic effects on the liver and kidneys.
Autor:
Haruka Kunimi, Naohiro Imura, Mayumi Sugimoto, Shin Abe, Tomoko Inubushi, Norio Kamemura, Atsushi Tabata, Haruka Hino
Publikováno v:
Fundamental Toxicological Sciences. 5:99-103
Autor:
Tomoko Inubushi, Naoko Watanabe, Tomohiro Takasawa, Kenji Aki, Yasue Tuboi, Nobuhiko Katunuma
Publikováno v:
BioFactors. 23:59-67
The mechanism of pellagrous changes in skin caused by a deficiency of vitamin B6 was studied in respect to neogenesis of proline in skin collagen and glucose metabolism. In vitamin B6 deficiency the insulin/glucagon coefficient in serum decreased sig
Publikováno v:
Biochemical and Biophysical Research Communications. 316:78-84
To clarify what kinds of proteinases are secreted into the foci of allergic-inflammation involving delayed-type hypersensitivity reaction, we examined the characteristic releases of various proteinases into the foci of Mycobacterium tuberculosis (M.
Autor:
Yasuo Ohba, A. Matsui, Dušan Turk, T. Asao, Hisao Kakegawa, Y. Tada, Nobuhiko Katunuma, E. Murata, Tomoko Inubushi, Vito Turk
Publikováno v:
Biochemical and Biophysical Research Communications. 267:850-854
We found that pyridoxal phosphate shows considerable inhibition of cathepsins. CLIK-071, in which the phosphate ester of position 3 of pyridoxal phosphate was replaced by propionate, strongly inhibited cathepsin B. Three new types of synthetic pyrido
Publikováno v:
BioFactors. 11:93-96
When mice were placed on diets extreme deficient in vitamin B6, ovalbumin-dependent antibody productions (IgE, IgG1, IgG2a) were significantly suppressed, and alanine aminotransferase activity in the liver was also significantly decreased. In the cas
Autor:
Yoichi Matsunaga, Midori Suenaga, Yutaka Nakaya, Jun Sakurai, Masataka Oda, Nagakatsu Harada, Nobuhiko Katunuma, Noriko Kamemura, Kazumi Ishidoh, Tomoko Inubushi
Publikováno v:
Journal of nutritional science and vitaminology. 58(6)
Ample evidence indicates that a high-protein/low-carbohydrate diet increases glucose energy expenditure and is beneficial in patients with type-2 diabetes mellitus (T2DM). The present study was designed to investigate the effects of L-tryptophan in T
Autor:
Yoichi Maekawa, A. Matsui, A. Sato, Nobuhiko Katunuma, M. Nakano, Koichi Endo, Kunisuke Himeno, Tomoko Inubushi, Y. Yuto, Y. Tada, J. Hanba, T. Asao
Publikováno v:
Biochemical and biophysical research communications. 272(1)
We reported that pyridoxal phosphate (PAP), a coenzyme form of vitamin B6, strongly inhibits activities of cathepsin B and weakly inhibits those of cathepsins S, K, and C in vitro. Either intraperitoneal injection or peroral administration of medicat
Autor:
T. Kakiuchi, Nobuhiko Katunuma, Yoichi Matsunaga, K. Endo, Yasuo Ohba, A. Matsui, T. Saibara, Tomoko Inubushi, Hisao Kakegawa
Publikováno v:
Advances in enzyme regulation. 38
Lysosomal cathepsin B plays an essential role in the processing of ovalbumin as an exogenous antigen to produce the complex between antigenic-peptide and major histocompatibility-complex class II. Administration of cathepsin B inhibitors, E-64, CA-07