Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Tomoko Hiroki"'
Autor:
Hiroko Kozuka-Hata, Tomoko Hiroki, Naoaki Miyamura, Aya Kitamura, Kouhei Tsumoto, Jun-ichiro Inoue, Masaaki Oyama
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 979 (2023)
Abnormal expression of histone deacetylases (HDACs) is reported to be associated with angiogenesis, metastasis and chemotherapy resistance regarding cancer in a wide range of previous studies. Suberoylanilide hydroxamic acid (SAHA) is well known to f
Externí odkaz:
https://doaj.org/article/0845311f48da417e939aac800dde0ee3
Autor:
Hiroko Kozuka-Hata, Aya Kitamura, Tomoko Hiroki, Aiko Aizawa, Kouhei Tsumoto, Jun-ichiro Inoue, Masaaki Oyama
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 411 (2020)
Post-translational modifications are known to be widely involved in the regulation of various biological processes, through the extensive diversification of each protein function at the cellular network level. In order to unveil the system-wide funct
Externí odkaz:
https://doaj.org/article/1fb209fcdc744a04977cae777e6706ef
Autor:
Masaaki Oyama, Hiroko Kozuka-Hata, Aiko Aizawa, Kouhei Tsumoto, Jun-ichiro Inoue, Tomoko Hiroki, Aya Kitamura
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 411 (2020)
Biomolecules
Volume 10
Issue 3
Biomolecules
Volume 10
Issue 3
Post-translational modifications are known to be widely involved in the regulation of various biological processes, through the extensive diversification of each protein function at the cellular network level. In order to unveil the system-wide funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babc4cd54e7660e7e78f3e8101cb87fa
https://www.mdpi.com/2218-273X/10/3/411
https://www.mdpi.com/2218-273X/10/3/411
Publikováno v:
Pediatrics international : official journal of the Japan Pediatric Society. 61(4)
Background Menkes disease (MNK; MIN 309400) is an X-linked recessive lethal disorder of copper metabolism caused by mutations in ATP7A (MIM 300011), which encodes a transmembrane copper-transporting P-type ATPase. This study assessed mutations in ATP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aec6075b5b52ab9f6011e73fe3a5c29
https://pubmed.ncbi.nlm.nih.gov/30809870
https://pubmed.ncbi.nlm.nih.gov/30809870
Autor:
Yoshiharu Sakai, Hiroyuki Daiko, Kazuhiko Aoyagi, Tsutomu Chiba, Manabu Muto, Masashi Tamaoki, Tomoko Hiroki, Takao Nishimura, Hiroki Sasaki, Keiko Minashi, Teruhiko Yoshida, Rie Komatsuzaki, Fumiko Chiwaki, Masayuki Komatsu, Kazuhiro Morishita, Hiroshi Seno
Publikováno v:
Cancer Science
Degree of histological differentiation is an important characteristic of cancers and may be associated with malignant potential. However, in squamous cell carcinomas, a key transcriptional factor regulating tumor differentiation is largely unknown. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4b536582d75f837cb4f4f28756f092
https://pubmed.ncbi.nlm.nih.gov/29427302
https://pubmed.ncbi.nlm.nih.gov/29427302
Autor:
Tsukasa Kodaira, Satoru Tomioka, Katsuyuki Nakajima, Shin-ichi Yatsuzuka, Kyoumi Nakazato, Kahoko Motoyama, Hiroko Kodama, Tomoko Hiroki, Takeaki Nagamine, Younosuke Shimomura, Mihoko Kato, Hidetoshi Saito
Publikováno v:
Journal of Trace Elements in Medicine and Biology. 28:441-447
We have developed an easy and specific enzyme-linked immunoassay (ELISA) for the simultaneous determination of serum metallothinein-1 (MT-1) and 2 (MT-2) in both humans and experimental animals. A competitive ELISA was established using a specific po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d951ee5729cf89ef829ebf35d7dd8ce5
https://doi.org/10.1016/j.jtemb.2014.07.013
https://doi.org/10.1016/j.jtemb.2014.07.013
Autor:
Yasuyoshi Watanabe, Satoshi Nozaki, Shiho Nomura, Satoshi Kudo, Haruo Shintaku, Taisuke Takeda, Takashi Hamazaki, Tomoko Hiroki, Chie Fujisawa, Emi Hayashinaka, Hiroko Kodama, Yasuhiro Wada, Eiichi Ninomiya
Publikováno v:
Journal of Nuclear Medicine. 55:845-851
Menkes disease (MD), an X-linked recessive disorder of copper metabolism caused by mutations in the copper-transporting ATP7A gene, results in growth failure and severe neurodegeneration in early childhood. Subcutaneous copper-histidine injection is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfd0d52d086917e718ad061550b91f0
https://doi.org/10.2967/jnumed.113.131797
https://doi.org/10.2967/jnumed.113.131797
Publikováno v:
Journal of Trace Elements in Medicine and Biology. 26:105-108
Menkes disease (MD) is a genetic neurodegenerative disorder characterized by copper deficiency due to a defect in ATP7A. Standard treatment involves parenteral copper-histidine administration. However, the treatment is ineffective if initiated after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6565f4439eda123d407623df616e1350
https://doi.org/10.1016/j.jtemb.2012.05.002
https://doi.org/10.1016/j.jtemb.2012.05.002
Publikováno v:
Nucleic Acids Research
The human vitamin D-binding protein (hDBP) gene is a member of a cluster that includes albumin, alpha-fetoprotein and alpha-albumin genes. The common origin, physical linkage and hepatic expression of these four genes predict shared regulatory elemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b940056126883989caade19f07be0b6b
https://doi.org/10.1093/nar/gkl174
https://doi.org/10.1093/nar/gkl174
Autor:
Mika Watanabe, Shigeru Tsuchiya, Chie Fujisawa, Mitsutoshi Munakata, Masazumi Nishikawa, Hiroko Kodama, Kazuhiko Kimura, Tomoko Hiroki
Publikováno v:
Pediatric research. 72(3)
Menkes disease (MD) is a disorder of copper transport caused by ATP7A mutations. Although parenteral copper supplements are partly effective in treating MD, the copper level in the brain remains insufficient, whereas copper accumulates in the kidney.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af38e6e5c62710cebf695d94e4b8beb
https://pubmed.ncbi.nlm.nih.gov/22728746
https://pubmed.ncbi.nlm.nih.gov/22728746