Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Tomoko Date"'
Independent evolution of multi-dominant viral genome species observed in a hepatitis C virus carrier
Autor:
Tomomi Ando, Hideki Aizaki, Masaya Sugiyama, Tomoko Date, Kazuhiko Hayashi, Masatoshi Ishigami, Yoshiaki Katano, Hidemi Goto, Masashi Mizokami, Masamichi Muramatsu, Makoto Kuroda, Takaji Wakita
Publikováno v:
Biochemistry and Biophysics Reports, Vol 32, Iss , Pp 101327- (2022)
The viral genome quasispecies composition of hepatitis C virus (HCV) could have important implications to viral pathogenesis and resistance to anti-viral treatment. The purpose of the present study was to profile the HCV RNA quasispecies. We develope
Externí odkaz:
https://doaj.org/article/d8441385e61544af99cc5acf4fcc144c
Autor:
Hiroshi Yokokawa, Midori Shinohara, Yuji Teraoka, Michio Imamura, Noriko Nakamura, Noriyuki Watanabe, Tomoko Date, Hideki Aizaki, Tomokatsu Iwamura, Hideki Narumi, Kazuaki Chayama, Takaji Wakita
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274283 (2022)
In recent years, new direct-acting antivirals for hepatitis C virus (HCV) have been approved, but hepatitis C continues to pose a threat to human health. It is important to develop neutralizing anti-HCV antibodies to prevent medical and accidental in
Externí odkaz:
https://doaj.org/article/eb687d3a76cf48d9a935c8025f9c022f
Autor:
Yoshihiro Matsumoto, Tomokazu Matsuura, Haruyo Aoyagi, Mami Matsuda, Su Su Hmwe, Tomoko Date, Noriyuki Watanabe, Koichi Watashi, Ryosuke Suzuki, Shizuko Ichinose, Kenjiro Wake, Tetsuro Suzuki, Tatsuo Miyamura, Takaji Wakita, Hideki Aizaki
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68992 (2013)
Glycyrrhizin (GL) has been used in Japan to treat patients with chronic viral hepatitis, as an anti-inflammatory drug to reduce serum alanine aminotransferase levels. GL is also known to exhibit various biological activities, including anti-viral eff
Externí odkaz:
https://doaj.org/article/161a0ca955a641a2968eb12862ddc32e
Autor:
Asako Murayama, Leiyun Weng, Tomoko Date, Daisuke Akazawa, Xiao Tian, Tetsuro Suzuki, Takanobu Kato, Yasuhito Tanaka, Masashi Mizokami, Takaji Wakita, Tetsuya Toyoda
Publikováno v:
PLoS Pathogens, Vol 6, Iss 4, p e1000885 (2010)
We have previously reported that the NS3 helicase (N3H) and NS5B-to-3'X (N5BX) regions are important for the efficient replication of hepatitis C virus (HCV) strain JFH-1 and viral production in HuH-7 cells. In the current study, we investigated the
Externí odkaz:
https://doaj.org/article/f6a9c9653b934510a177740b306138f2
Autor:
Hideki Aizaki, Takaji Wakita, Guofeng Cheng, Noriyuki Watanabe, Su Su Hmwe, William Delaney, Masaya Sugiyama, Tomoko Date, Masamichi Muramatsu, Hussein Aly Hussan, Takaya Suzuki, Masashi Mizokami
Publikováno v:
The Journal of general virology. 101(2)
To establish infectious genotype 4a (GT4a) cell culture-derived hepatitis C virus (HCVcc), we constructed full-length ED43 and 12 mutants possessing single or double mutations that increase ED43 replicon replication, and performed cell culture after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf6ac758ee5a71155b5e1c9b9652625
https://pubmed.ncbi.nlm.nih.gov/31859613
https://pubmed.ncbi.nlm.nih.gov/31859613
Autor:
T Kanto, Tatsuji Maeshiro, Hiroshi Sakugawa, Masashi Mizokami, Masaya Sugiyama, D. Shibata, Akira Hokama, Tomoko Date, Shingo Arakaki, Kunikazu Hoshino, Jiro Fujita, Shuichi Maruwaka
Publikováno v:
Journal of Viral Hepatitis. 25:976-985
Okinawa Island, located in Southern Japan, has a higher prevalence rate of hepatitis C virus subtype 1a (HCV-1a) infection than that in mainland Japan. Okinawa has a history of US military occupation after World War II. To elucidate the transmission
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a8c0892966a54aaa70ab90079e96c1
https://doi.org/10.1111/jvh.12898
https://doi.org/10.1111/jvh.12898
Autor:
Takanobu Kato, Tomoko Date, Masashi Mizokami, Junko Kato, Yasuhito Tanaka, Keiko Tanaka-Kaneko, Kenichi Morikawa, Asako Murayama, Daisuke Akazawa, Tetsutaro Sata, Hitoshi Takahashi, Takaji Wakita
Publikováno v:
Journal of Virology. 86:10805-10820
Although the recently developed infectious hepatitis C virus system that uses the JFH-1 clone enables the study of whole HCV viral life cycles, limited particular HCV strains have been available with the system. In this study, we isolated another gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40bfb214190e4d7fbbdc3e1aaf3f678b
https://doi.org/10.1128/jvi.07235-11
https://doi.org/10.1128/jvi.07235-11
Autor:
Masashi Mizokami, Yasuhito Tanaka, Osamu Yokosuka, Daisuke Akazawa, Tomoko Date, Shingo Nakamoto, Akio Nomoto, Asako Murayama, Takaji Wakita, Takanobu Kato, Nao Sugiyama, Takahiro Masaki
Publikováno v:
Journal of Virology. 86:2143-2152
To establish a cell culture system for chimeric hepatitis C virus (HCV) genotype 2b, we prepared a chimeric construct harboring the 5′ untranslated region (UTR) to the E2 region of the MA strain (genotype 2b) and the region of p7 to the 3′ UTR of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20aa72dd4df15821c83fe921f85b7643
https://doi.org/10.1128/jvi.05386-11
https://doi.org/10.1128/jvi.05386-11
Autor:
Tomoko Date, Takaji Wakita, Hidenori Mochizuki, Noriaki Omi, Noriko Nakamura, Tetsuro Suzuki, Hitoshi Takahashi, Koji Ishii, Kenichi Morikawa, Daisuke Akazawa
Publikováno v:
Vaccine. 29:4821-4828
Hepatitis C virus (HCV) is a major cause of liver cancer, and it is therefore important to develop a prophylactic strategy for HCV infection. In recent years, a system for cell culture of the infectious HCV particle has been established, and the inac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8ee222483c8d3a0df322b72d568b0b
https://doi.org/10.1016/j.vaccine.2011.04.069
https://doi.org/10.1016/j.vaccine.2011.04.069
Autor:
Tetsuro Suzuki, Tomoko Date, Takanobu Kato, Hidenori Mochizuki, Hitoshi Takahashi, Masayuki Shirakura, Keiko Tanaka-Kaneko, Tetsutaro Sata, Masashi Mizokami, Yasuhito Tanaka, Takaji Wakita, Daisuke Akazawa, Noriko Nakamura
Publikováno v:
Biochemical and Biophysical Research Communications. 395:565-571
To establish a simple system for purification of recombinant infectious hepatitis C virus (HCV) particles, we designed a chimeric J6/JFH-1 virus with a FLAG (FL)-epitope-tagged sequence at the N-terminal region of the E2 hypervariable region-1 (HVR1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4f40c6692073e33c46e2743c6e1b28
https://doi.org/10.1016/j.bbrc.2010.04.081
https://doi.org/10.1016/j.bbrc.2010.04.081