Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tomoko Nii-Kono"'
Autor:
Tadao Akizawa, Kazuhiro Shiizaki, Qunsheng Yuan, Ikuji Hatamura, Fumie Saji, Tomoko Nii-Kono, Takashi Shigematsu, Masafumi Fukagawa
Publikováno v:
American Journal of Nephrology. 28:59-66
Aims: In this study, we investigated the effects of direct injection (DI) of calcitriol or maxacalcitol into the hyperplastic parathyroid gland (PTG) on altered gene expression related to the advanced status of secondary hyperparathyroidism (SHPT). M
Autor:
Hideyuki Yamato, Kiyoshi Kurokawa, Masafumi Fukagawa, Tomoko Nii-Kono, Yoshiko Iwasaki-Ishizuka
Publikováno v:
Nephrology Dialysis Transplantation. 20:1904-1911
Background. Adynamic bone disease (ABD), which is characterized by reduced bone formation and resorption, has become an increasingly common manifestation of bone abnormalities in patients with end-stage renal failure. It has been recognized that skel
Autor:
Hirotaka Komaba, Hideki Fujii, Yasuhiro Hamada, Daisuke Tsuchihashi, Motoko Tanaka, Masafumi Fukagawa, Takaya Abe, Tomoko Nii-Kono
Publikováno v:
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. 12(3)
Hepcidin has recently been recognized as a hormone essential to the negative regulation of iron. Synthesis of hepcidin is increased by iron overload or inflammation, and decreased by iron deficiency, anemia and erythropoietin. Dialysis patients frequ
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 23(6)
Background. Recombinant human erythropoietin (rHuEpo) is a definitive treatment for anaemia in chronic kidneydisease(CKD).Duringlong-termrHuEpotreatment most patients develop and show persistent iron deficiency in spite of oral iron supplementation.
Autor:
Riko Kitazawa, Masafumi Fukagawa, Hajime Nakamura, Masato Kasuga, Shigemitu Ueyama, Michiru Fukunaga, Satoshi Miyata, Tomoko Nii-Kono, Sohei Kitazawa, Yasuhiro Hamada, Satomi Higo, Junji Yodoi
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 22(6)
Background. Oxidative stress has been suggested to play an important role in the pathogenesis of diabetic nephropathy. In the present study, the effects of thioredoxin1 (TRX1) overexpression, a small protein with antioxidant property, on the developm
Autor:
Ayako Fujieda, Atsuko Hosokawa, Masafumi Fukagawa, Hideyuki Yamato, Motoyuki Uchida, Tomoko Nii-Kono, Masaru Motojima, Yoshiko Iwasaki
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 21(10)
Background. Using a rat model of renal failure with normal parathyroid hormone levels, we had demonstrated previously that bone formation decreased depending on the degree of renal dysfunction, and hypothesized that uraemic toxins (UTx) are associate
Publikováno v:
Europe PubMed Central
Autor:
Atsuko Hosokawa, Masafumi Fukagawa, Masaru Motojima, Motoyuki Uchida, Tomoko Nii-Kono, Ayako Fujieda, Hideyuki Yamato, Yoshiko Iwasaki
Publikováno v:
Journal of bone and mineral metabolism. 24(2)
Patients with end-stage renal disease (ESRD) develop various kinds of abnormalities in bone and mineral metabolism, widely known as renal osteodystrophy (ROD). Although the pathogenesis of ESRD may be similar in many patients, the response of the bon
Autor:
Akihide Tokumoto, Tomoko Nii-Kono, Tomoyuki Okada, Takashi Shigematsu, Junichiro James Kazama, Masafumi Fukagawa, Fumihiko Koiwa, Noritaka Onoda, Hitoshi Kato
Publikováno v:
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. 9(4)
Fibroblast growth factor 23 (FGF23) is a member of the fibroblast growth factor superfamily which displays a strong phosphaturic action and an inhibition of vitamin D 1-alpha hydroxylase activity. Fourty-six patients undergoing maintenance hemodialys
Publikováno v:
Current opinion in nephrology and hypertension. 14(4)
This review summarizes the molecular properties and biological roles of a new phosphaturic factor, fibroblast growth factor 23 (FGF23). Significant roles of FGF23 are discussed, especially in terms of its effects on the kidney, the main target organ.