Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tomoko, Kamasaki"'
Autor:
Tomokazu Tamura, Daichi Yamasoba, Yoshitaka Oda, Jumpei Ito, Tomoko Kamasaki, Naganori Nao, Rina Hashimoto, Yoichiro Fujioka, Rigel Suzuki, Lei Wang, Hayato Ito, Yukie Kashima, Izumi Kimura, Mai Kishimoto, Masumi Tsuda, Hirofumi Sawa, Kumiko Yoshimatsu, Yuki Yamamoto, Tetsuharu Nagamoto, Jun Kanamune, Yutaka Suzuki, Yusuke Ohba, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Isao Yokota, Keita Matsuno, Kazuo Takayama, Shinya Tanaka, Kei Sato, Takasuke Fukuhara
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract The unremitting emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants necessitates ongoing control measures. Given its rapid spread, the new Omicron subvariant BA.5 requires urgent characterization. Here, we comp
Externí odkaz:
https://doaj.org/article/56751a9096cb4cad97f0a35f52e2a2d2
Autor:
Tomoko Kamasaki, Yumi Miyazaki, Susumu Ishikawa, Kazuya Hoshiba, Keisuke Kuromiya, Nobuyuki Tanimura, Yusuke Mori, Motosuke Tsutsumi, Tomomi Nemoto, Ryota Uehara, Shiro Suetsugu, Toshiki Itoh, Yasuyuki Fujita
Publikováno v:
iScience, Vol 24, Iss 9, Pp 102994- (2021)
Summary: At the initial stage of carcinogenesis, cell competition often occurs between newly emerging transformed cells and the neighboring normal cells, leading to the elimination of transformed cells from the epithelial layer. For instance, when Ra
Externí odkaz:
https://doaj.org/article/fa958811e0e047c3bf59653c4f1490e6
Publikováno v:
Microscopy. 71:195-205
A small number of oncogenic mutated cells sporadically arise within the epithelial monolayer. Newly emerging Ras- or Src-transformed epithelial cells are often apically eliminated during competitive interactions between normal and transformed cells.
Autor:
Eilma Akter, Yukihiro Tasaki, Yusuke Mori, Kazuki Nakai, Kazuki Hachiya, Hancheng Lin, Masamitsu Konno, Tomoko Kamasaki, Kenji Tanabe, Yumi Umeda, Shotaro Yamano, Yasuyuki Fujita, Shunsuke Kon
Publikováno v:
Cell reports. 40(9)
Cell competition is a process by which unwanted cells are eliminated from tissues. Apical extrusion is one mode whereby normal epithelial cells remove transformed cells, but it remains unclear how this process is mechanically effected. In this study,
Autor:
Keisuke Kuromiya, Kana Aoki, Kojiro Ishibashi, Moe Yotabun, Miho Sekai, Nobuyuki Tanimura, Sayuri Iijima, Susumu Ishikawa, Tomoko Kamasaki, Yuki Akieda, Tohru Ishitani, Takashi Hayashi, Satoshi Toda, Koji Yokoyama, Chol Gyu Lee, Ippei Usami, Haruki Inoue, Ichigaku Takigawa, Estelle Gauquelin, Kaoru Sugimura, Naoya Hino, Yasuyuki Fujita
Publikováno v:
Cell Reports. 40:111078
In vertebrates, newly emerging transformed cells are often apically extruded from epithelial layers through cell competition with surrounding normal epithelial cells. However, the underlying molecular mechanism remains elusive. Here, using phospho-SI
Autor:
Yusuke Mori, Yoichiro Tamori, Mihoko Kajita, Koki Kohashi, Susumu Ishikawa, Tomoko Kamasaki, Kei Kozawa, Rika Narumi, Yasuyuki Fujita, Rei Kobayashi
Publikováno v:
Current Biology. 31:3984-3995.e5
At the initial stage of carcinogenesis, newly emerging transformed cells are often eliminated from epithelial layers via cell competition with the surrounding normal cells. For instance, when surrounded by normal cells, oncoprotein RasV12-transformed
Autor:
Keisuke Kuromiya, Hironori Suzuki, Kozo Kaibuchi, Shoko Ito, Makoto Tsunoda, Shinya Tanaka, Tomonori Nakamura, Tomoyoshi Soga, Koki Kohashi, Miho Sekai, Mai Kakeno, Susumu Ishikawa, Mishie Tanino, Tomoko Kamasaki, Kei Kozawa, Yohei Mukai, Atsushi Enomoto, Mitinori Saitou, Kenkyo Matsuura, Nanami Sato, Yukihiro Yabuta, Noriko Gotoh, Nobuyuki Tanimura, Yasuyuki Fujita, Hiroaki Sako, Takanobu Shirai, Takeshi Maruyama, Kenji Ohba, Yasuyuki Mizutani, Shota Asano, Tadashi Iida, Takahiro Ito, Toyone Kikumori, Ken Natsuga, Yuki Miyai
Publikováno v:
Current Biology. 31:3086-3097.e7
Summary At the early stage of cancer development, oncogenic mutations often cause multilayered epithelial structures. However, the underlying molecular mechanism still remains enigmatic. By performing a series of screenings targeting plasma membrane
Autor:
Jun-ichi Miyazaki, Masaru Ishii, Shunsuke Kon, Michael R. Duchen, Tomohiro Matsumoto, Eisuke Nishida, Masanobu Oshima, Riku Egami, Tomoko Kamasaki, Hiroto Katoh, Yusuke Ohba, Mihoko Kajita, Shingo Yoshioka, Rika Narumi, Takanobu Shirai, Tomoko Morita, Junichi Kikuta, Yoshiteru Sasaki, Toshiro Sato, Kojiro Ishibashi, Sato Honma, Sho Kitamoto, Yasuyuki Fujita, Ayana Sasaki, Hirotaka Watanabe, Masamichi Imajo, Susumu Ishikawa, Ryosuke Enoki, Shinya Tanaka, Jin Min Nam, Ikumi Kameda, Yasuhito Onodera, Hajime Yamauchi, Takeshi Maruyama, Hiromi Imamura, Atsuko Nishikawa, Yoichiro Fujioka, Tomoyoshi Soga, Yuta Yako
Publikováno v:
Nature Cell Biology. 19:530-541
Recent studies have revealed that newly emerging transformed cells are often apically extruded from epithelial tissues. During this process, normal epithelial cells can recognize and actively eliminate transformed cells, a process called epithelial d
Autor:
Junichiro Yajima, Ryota Uehara, Shota Hiruma, Gohta Goshima, Daniel W. Gerlich, Ina Poser, Tomoko Kamasaki, Kinya Yoda
Publikováno v:
Molecular Biology of the Cell
Perturbations of the central spindle by depletion of a microtubule nucleation regulator, augmin, revealed its unexpected contributions to the control of cleavage furrow ingression, as well as to cytokinesis completion. These are achieved through nonr
Autor:
Tomoko Kamasaki, Mihoko Kajita, Takeshi Maruyama, Mikio Takagi, Takashi Shimada, Yasuyuki Fujita, Susumu Ishikawa, Masaya Ikegawa
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 23(11)
At the initial stage of carcinogenesis, transformation occurs in single cells within the epithelium. Recent studies have revealed that the newly emerging transformed cells are often apically eliminated from epithelial tissues. However, the underlying