Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tomoki Otani"'
Autor:
Kei Miyamoto, Khoi T. Nguyen, George E. Allen, Jerome Jullien, Dinesh Kumar, Tomoki Otani, Charles R. Bradshaw, Frederick J. Livesey, Manolis Kellis, John B. Gurdon
Publikováno v:
Cell Reports, Vol 24, Iss 2, Pp 304-311 (2018)
Summary: Oocytes have a remarkable ability to reactivate silenced genes in somatic cells. However, it is not clear how the chromatin architecture of somatic cells affects this transcriptional reprogramming. Here, we investigated the relationship betw
Externí odkaz:
https://doaj.org/article/ca56751c6eef410796572fb95a15ed4d
Autor:
Kei Miyamoto, George E. Allen, Manolis Kellis, John B. Gurdon, Khoi T. Nguyen, Tomoki Otani, Frederick J. Livesey, Jerome Jullien, Dinesh Kumar, Charles R. Bradshaw
Publikováno v:
Cell Reports
Elsevier
Cell Reports, Vol 24, Iss 2, Pp 304-311 (2018)
Elsevier
Cell Reports, Vol 24, Iss 2, Pp 304-311 (2018)
Summary Oocytes have a remarkable ability to reactivate silenced genes in somatic cells. However, it is not clear how the chromatin architecture of somatic cells affects this transcriptional reprogramming. Here, we investigated the relationship betwe
Autor:
Juergen A. Knoblich, Nina S. Corsini, Frederick J. Livesey, Madeline A. Lancaster, E. Hilary Gustafson, Alex W Phillips, Tomoki Otani, Simone Wolfinger, Thomas R Burkard
Publikováno v:
Nature Biotechnology
Three-dimensional cell culture models have either relied on the self-organizing properties of mammalian cells or used bioengineered constructs to arrange cells in an organ-like configuration. While self-organizing organoids excel at recapitulating ea
Autor:
Gerit A. Linneweber, Tomoki Otani, Bruno Hudry, Michaela Yuan, Elisabeth Knust, Irene Miguel-Aliaga, Mario de Bono, Jake Jacobson, Dirk Dormann, Christo P. Christov, Karl Emanuel Busch
Publikováno v:
Cell
Linneweber, G A, Jacobson, J, Busch, K E, Hudry, B, Christov, C P, Dormann, D, Yuan, M, Otani, T, Knust, E, de Bono, M & Miguel-Aliaga, I 2014, ' Neuronal Control of Metabolism through Nutrient-Dependent Modulation of Tracheal Branching ', Cell, vol. 156, no. 1-2, pp. 69-83 . https://doi.org/10.1016/j.cell.2013.12.008
Linneweber, G A, Jacobson, J, Busch, K E, Hudry, B, Christov, C P, Dormann, D, Yuan, M, Otani, T, Knust, E, de Bono, M & Miguel-Aliaga, I 2014, ' Neuronal Control of Metabolism through Nutrient-Dependent Modulation of Tracheal Branching ', Cell, vol. 156, no. 1-2, pp. 69-83 . https://doi.org/10.1016/j.cell.2013.12.008
Summary During adaptive angiogenesis, a key process in the etiology and treatment of cancer and obesity, the vasculature changes to meet the metabolic needs of its target tissues. Although the cues governing vascular remodeling are not fully understo
Autor:
Christoph M. Wintersteiger, Boyan Yordanov, Hillel Kugler, Tomoki Otani, Youssef Hamadi, Sara-Jane Dunn, Yoli Shavit, Frederick J. Livesey
Publikováno v:
Bio Systems. 146
Studying the gene regulatory networks (GRNs) that govern how cells change into specific cell types with unique roles throughout development is an active area of experimental research. The fate specification process can be viewed as a biological progr
Autor:
E. Hilary Gustafson, Nina S. Corsini, Simone Wolfinger, Madeline A. Lancaster, Tomoki Otani, Thomas R Burkard, Frederick J. Livesey, Alex W Phillips, Juergen A. Knoblich
Publikováno v:
Nature Biotechnology. 36:1016-1016
Nat. Biotechnol. 35, 659–666 (2017); published online 31 May 2017; corrected after print 14 August 2018 In the HTML and PDF versions of this article initially published, μ's appeared as m's throughout the scale bar lengths in the figure legends, a
Publikováno v:
Cell stem cell. 18(4)
Variation in cerebral cortex size and complexity is thought to contribute to differences in cognitive ability between humans and other animals. Here we compare cortical progenitor cell output in humans and three nonhuman primates using directed diffe