Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Tomoki Ito"'
Autor:
Yutaro Nasa, Atsushi Satake, Ryohei Tsuji, Ryo Saito, Yukie Tsubokura, Hideaki Yoshimura, Tomoki Ito
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDefective interleukin-2 (IL-2) production contributes to immune system imbalance in patients with systemic erythematosus lupus (SLE). Recent clinical studies suggested that low-dose IL-2 treatment is beneficial for SLE and the therapeutic
Externí odkaz:
https://doaj.org/article/b4b5df40c8834117b0f048a347d078ab
Autor:
Yutaka Shimazu, Junya Kanda, Satoru Kosugi, Tomoki Ito, Hitomi Kaneko, Kazunori Imada, Yuji Shimura, Shin-ichi Fuchida, Kentaro Fukushima, Hirokazu Tanaka, Satoshi Yoshihara, Kensuke Ohta, Nobuhiko Uoshima, Hideo Yagi, Hirohiko Shibayama, Ryosuke Yamamura, Yasuhiro Tanaka, Hitoji Uchiyama, Yoshiyuki Onda, Yoko Adachi, Hitoshi Hanamoto, Ryoichi Takahashi, Mitsuhiro Matsuda, Takashi Miyoshi, Teruhito Takakuwa, Masayuki Hino, Naoki Hosen, Shosaku Nomura, Chihiro Shimazaki, Itaru Matsumura, Akifumi Takaori-Kondo, Junya Kuroda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Novel therapeutic drugs have dramatically improved the overall survival of patients with multiple myeloma. We sought to identify the characteristics of patients likely to exhibit a durable response to one such drug, elotuzumab, by analyzing
Externí odkaz:
https://doaj.org/article/f9f360c7a7b8496ea74ce32ada6c5c4d
Publikováno v:
Case Reports in Acute Medicine, Vol 5, Iss 2-3, Pp 6-11 (2022)
Epigastric pain is a common complaint in the emergency department (ED). Clinicians require skills to differentiate the epigastric pain in the ED. Here, we report a case of acute esophageal necrosis (AEN) as a cause of epigastric pain in the ED. An 83
Externí odkaz:
https://doaj.org/article/c614b9b71fb542ff967503651ff29444
Autor:
Yoshihisa Ishiura, Shosaku Nomura, Yuka Ishii, Kai Imai, Yusuke Sawai, Takeshi Tamaki, Toshiki Shimizu, Naoyuki Miyashita, Tomoki Ito
Publikováno v:
Journal of International Medical Research, Vol 51 (2023)
Cough is a frequent symptom accompanied by lung cancer. More potent antitussive treatment for this complex and distressing symptom is required, but anti-cancer chemotherapy cannot fully manage the cough. Inhibition of vagal nerves might control cough
Externí odkaz:
https://doaj.org/article/f3b7660d16eb4ed0b363e9189bf40da3
Autor:
Shosaku Nomura MD, Jun Ichikawa MD, Toshiki Shimizu MD, Yoshihisa Ishiura MD, Masaya Okada MD, Kazuyoshi Ishii MD, Tomoki Ito MD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 29 (2023)
Thrombotic complications after allogeneic hematopoietic stem cell transplantation (allo-HSCT) significantly impact transplant outcomes. We focused on high mobility group box-protein (HMGB)1, one causative agent of thrombotic lesions in allo-HSCT, and
Externí odkaz:
https://doaj.org/article/1b625e0a2724403a890918efa4700302
Autor:
Aya Nakaya, Hirohiko Shibayama, Nobuhiko Uoshima, Ryosuke Yamamura, Satoshi Yoshioka, Kazunori Imada, Yuji Shimura, Masaaki Hotta, Toshimitsu Matsui, Satoru Kosugi, Hitoshi Hanamoto, Hitoji Uchiyama, Satoshi Yoshihara, Shin-ichi Fuchida, Yoshiyuki Onda, Yasuhiro Tanaka, Kensuke Ohta, Mitsuhiro Matsuda, Junya Kanda, Adachi Yoko, Miki Kiyota, Eri Kawata, Ryoichi Takahashi, Kentaro Fukushima, Hirokazu Tanaka, Hideo Yagi, Teruhito Takakuwa, Naoki Hosen, Tomoki Ito, Chihiro Shimazaki, Akifumi Takaori-Kondo, Junya Kuroda, Itaru Matsumura, Masayuki Hino
Publikováno v:
Leukemia Research Reports, Vol 20, Iss , Pp 100395- (2023)
To evaluate the specific prognostic value of CAs, we conducted an analysis of 923 symptomatic multiple myeloma patients. Among this cohort, 480 patients had complete data set of high-risk CAs by interphase fluorescent in situ hybridization at diagnos
Externí odkaz:
https://doaj.org/article/82b016d7b6d64623a8db970348a6c492
Autor:
Shuji Uno, Shuichi Midorikawa, Kei Inoue, Daisuke Ichikawa, Tomoki Ito, Junya Kuroda, Kenshi Suzuki
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285947 (2023)
Despite recent advances in the range of therapies available for the treatment of multiple myeloma (MM), there are limited data surrounding survival outcomes and baseline characteristics influencing survival in general clinical practice in Japan. The
Externí odkaz:
https://doaj.org/article/51e39cf0896e4fffbf33cb42acd1808e
Autor:
Yutaka Shimazu, Junya Kanda, Hitomi Kaneko, Kazunori Imada, Ryosuke Yamamura, Satoru Kosugi, Yuji Shimura, Tomoki Ito, Shin-ichi Fuchida, Hitoji Uchiyama, Kentaro Fukushima, Satoshi Yoshihara, Hitoshi Hanamoto, Hirokazu Tanaka, Nobuhiko Uoshima, Kensuke Ohta, Hideo Yagi, Hirohiko Shibayama, Yoshiyuki Onda, Yasuhiro Tanaka, Yoko Adachi, Mitsuhiro Matsuda, Masato Iida, Takashi Miyoshi, Toshimitsu Matsui, Ryoichi Takahashi, Teruhito Takakuwa, Masayuki Hino, Naoki Hosen, Shosaku Nomura, Chihiro Shimazaki, Itaru Matsumura, Akifumi Takaori-Kondo, Junya Kuroda
Publikováno v:
Therapeutic Advances in Hematology, Vol 13 (2022)
Background: Daratumumab is one of the most widely used treatments for relapsed/refractory multiple myeloma (MM) patients. However, not all patients achieve a lasting therapeutic response with daratumumab. Objectives: We hypothesized that a durable re
Externí odkaz:
https://doaj.org/article/de0e47159d65497ba083e4d809b5a35a
Autor:
Aya Nakaya, Hirohiko Shibayama, Eiji Nakatani, Yuji Shimura, Satoru Kosugi, Hirokazu Tanaka, Shin‐Ichi Fuchida, Junya Kanda, Nobuhiko Uoshima, Hitomi Kaneko, Kazunori Imada, Kensuke Ohta, Tomoki Ito, Hideo Yagi, Satoshi Yoshihara, Masayuki Hino, Chihiro Shimazaki, Akifumi Takaori‐Kondo, Junya Kuroda, Itaru Matsumura, Yuzuru Kanakura, Shosaku Nomura
Publikováno v:
eJHaem, Vol 2, Iss 4, Pp 765-773 (2021)
Abstract A total of 129 symptomatic patients with multiple myeloma (MM) who underwent high‐dose chemotherapy with autologous stem cell transplantation (HDT/ASCT) were analyzed. The 4‐year overall survival (OS) of patients with maintenance (n = 82
Externí odkaz:
https://doaj.org/article/fca8d9086da64417a2e3ae2412495e6f
Autor:
Yukie Tsubokura, Hideaki Yoshimura, Atsushi Satake, Yutaro Nasa, Ryohei Tsuji, Tomoki Ito, Shosaku Nomura
Publikováno v:
Immunity, Inflammation and Disease, Vol 10, Iss 9, Pp n/a-n/a (2022)
Abstract Introduction Allogeneic hematopoietic stem cell transplantation (aHSCT) is a curative treatment for hematopoietic malignancies. Graft‐versus‐host disease (GVHD) is a major complication of aHSCT. After transplantation, the balance of immu
Externí odkaz:
https://doaj.org/article/bf1d500e6eb84dae8a726a2d42cb6fb9