Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tomoki, Omodani"'
Autor:
Takaaki Sumiyoshi, Yusuke Sawayama, Tomohiro Nigo, Motoji Kawasaki, Takeshi Ochi, Masashi Nakao, Tomoki Omodani
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 57:477-479
We describe here the synthesis of [14C]-2-(3-chlorophenyloxy)-3-[3-(3-hydroxy)pyridin-4-yl propoxy]pyridine (1), a phosphodiesterase 4 inhibitor. [14C]-Labeled 1 was prepared in three steps from [14C]-2-bromopyridin-3-ol in an overall yield of 32%. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ac2ce8217117c426c3e6da72de00822
https://doi.org/10.1002/jlcr.3211
https://doi.org/10.1002/jlcr.3211
Publikováno v:
Tetrahedron: Asymmetry. 21:1855-1860
We have successfully synthesized chiral β-amino trifluoromethyl alcohol (2S,3S)-7a, which is a key intermediate in the production of AE-3763, by stereoselective reduction of N-Cbz-protected 5-hydroxy-5-(trifluoromethyl)-1,3-oxazolidine 4 prepared fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22ff9b6e46e0d5038402c403563fa9b8
https://doi.org/10.1016/j.tetasy.2010.06.038
https://doi.org/10.1016/j.tetasy.2010.06.038
Autor:
Hiroshi Okazaki, Yasunao Inoue, Takemura Tadashi, Tomoki Omodani, Sato Fuminori, Komiya Masanobu, Kiyomi Imano
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:551-555
In our search for a new agent, human neutrophil elastase (HNE) inhibitor, for the treatment of acute respiratory failure, we rationally designed and synthesized a series of peptide-based carboxylic acid-containing transition-state inhibitors. The pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03e40c969ba2253230952acd9ae1d86
https://doi.org/10.1016/s0960-894x(01)00797-1
https://doi.org/10.1016/s0960-894x(01)00797-1
Autor:
Takeshi, Ochi, Yusuke, Sawayama, Motoji, Kawasaki, Tomohiro, Nigo, Masashi, Nakao, Tomoki, Omodani, Takaaki, Sumiyoshi
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 57(7)
We describe here the synthesis of [(14)C]-2-(3-chlorophenyloxy)-3-[3-(3-hydroxy)pyridin-4-yl propoxy]pyridine (1), a phosphodiesterase 4 inhibitor. [(14)C]-Labeled 1 was prepared in three steps from [(14)C]-2-bromopyridin-3-ol in an overall yield of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2691e89e3d9a481f3bea4200cca0abca
https://pubmed.ncbi.nlm.nih.gov/24966159
https://pubmed.ncbi.nlm.nih.gov/24966159
Autor:
Kimiko Nakano, Noriko Wariishi, Yoshihisa Takaishi, Kozo Shishido, Masayuki Shibuya, Yukihisa Ono, Tomoki Omodani, Kiyoto Goto, Hideo Tateishi
Publikováno v:
Phytochemistry. 35:731-737
Seven new quinoide-type diterpenes were isolated from the stems of Tripterygium wilfordii var. regelii and their structures were established on the basis of spectroscopic and chemical evidence. The isolated compounds showed extremely potent inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a0095af77973fc08444173e1dd9eba4
https://doi.org/10.1016/s0031-9422(00)90596-x
https://doi.org/10.1016/s0031-9422(00)90596-x
Publikováno v:
Chemistry Letters. 22:557-560
Employing a strategy for the construction of fused furans based on an intramolecular [3+2] dipolar cycloaddition reaction of nitrile oxide, the BCD ring system 3 found in the tanshinone family as a common structural unit has been synthesized.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd459ce693c2de774a8cd229212c4be5
https://doi.org/10.1246/cl.1993.557
https://doi.org/10.1246/cl.1993.557
Publikováno v:
ChemInform. 22
Two drimane type sesquiterpenoids, (+)-drimane-8,11-diol 1 and (+)-drim-9(11)-en-8-ol 2, have been synthesized in an optically pure form starting from geraniol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088fbc92056e875f77ca90e20132b6ad
https://doi.org/10.1002/chin.199149243
https://doi.org/10.1002/chin.199149243
Publikováno v:
ChemInform. 23
A practical synthesis of the epoxy carboxylic acid 4, the left-hand segment of azinomycins, and its conversion into the naturally occurring amide 3 have been achieved enantioselectively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49b61f47a1923d0fcf2b21c8ea0c9ce7
https://doi.org/10.1002/chin.199247262
https://doi.org/10.1002/chin.199247262
Publikováno v:
HETEROCYCLES. 47:81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0863dd321d4bfbe8b2fa60afb74a4ae1
https://doi.org/10.3987/com-97-s(n)20
https://doi.org/10.3987/com-97-s(n)20
Autor:
Tomoki Omodani, Kozo Shishido
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :2781
The first enantioselective total synthesis of (–)-nanaimoal 1 has been achieved from geraniol and the absolute configuration of the only existing quaternary stereogenic centre was found to be (R).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8d18ce4ccbc992e042683c3a6ea505d
https://doi.org/10.1039/c39940002781
https://doi.org/10.1039/c39940002781