Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Tomoki, HASHIMOTO"'
Autor:
Peyton L. Nisson, Michael T. Lawton, Oscar Cisneros, Takuma Maeda, Nestor R. Gonzalez, Juhana Frösen, Tomoki Hashimoto
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 23 (2024)
Background Aneurysms are one of the most common and yet devastating cerebrovascular diseases after rupture. Despite several decades of scientific advancements including the expansion of the endovascular capabilities and noninvasive imaging modalities
Externí odkaz:
https://doaj.org/article/492c2b9af314493899260f1c8473b7ad
Autor:
Dilaware Khan, Xuanchen Li, Tomoki Hashimoto, Rokuya Tanikawa, Mika Niemela, Michael Lawton, Sajjad Muhammad
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)
Intracranial aneurysms (IAs) are rare vascular lesions that are more frequently found in women. The pathophysiology behind the formation and growth of IAs is complex. Hence, to date, no single pharmacological option exists to treat them. Animal model
Externí odkaz:
https://doaj.org/article/abda606c57764480a5e6da27fea4f961
Autor:
Nisson, Peyton L., Lawton, Michael T., Cisneros, Oscar, Maeda, Takuma, Gonzalez, Nestor R., Frösen, Juhana, Tomoki Hashimoto
Publikováno v:
Journal of the American Heart Association; 12/3/2024, Vol. 13 Issue 23, p1-18, 18p
Autor:
Stephanie Cicalese, Keiichi Torimoto, Keisuke Okuno, Katherine J. Elliott, Victor Rizzo, Tomoki Hashimoto, Satoru Eguchi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 23 (2022)
Background Investigations into alternative treatments for hypertension are necessary because current treatments cannot fully reduce the risk for the development of cardiovascular diseases. Chronic activation of unfolded protein response attributable
Externí odkaz:
https://doaj.org/article/d42bb8540a894e0c872e03e94b55db18
Autor:
Keisuke Okuno, Keiichi Torimoto, Stephanie M. Cicalese, Kyle Preston, Victor Rizzo, Tomoki Hashimoto, Thomas M. Coffman, Matthew A. Sparks, Satoru Eguchi
Publikováno v:
Hypertension. 80:668-677
Background: Ang II (angiotensin II) type 1 (AT 1 ) receptors play a critical role in cardiovascular diseases such as hypertension. Rodents have 2 types of AT 1 receptor (AT 1A and AT 1B ) of which knock-in Tagln -mediated smooth muscle AT 1A silencin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4f8c26e90d63ba7d1c00e3934337988
https://doi.org/10.1161/hypertensionaha.122.20601
https://doi.org/10.1161/hypertensionaha.122.20601
Autor:
Khan, Dilaware, Xuanchen Li, Tomoki Hashimoto, Rokuya Tanikawa, Niemela, Mika, Lawton, Michael, Muhammad, Sajjad
Publikováno v:
Journal of the American Heart Association; 2/6/2024, Vol. 13 Issue 3, p1-11, 11p
Autor:
Keisuke Okuno, Keiichi Torimoto, Stephanie M. Cicalese, Tomoki Hashimoto, Matthew A. Sparks, Victor Rizzo, Satoru Eguchi
Publikováno v:
Journal of Molecular and Cellular Cardiology. 176:55-57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24fa29d74010a4f282ed57869dd0195e
https://doi.org/10.1016/j.yjmcc.2023.01.013
https://doi.org/10.1016/j.yjmcc.2023.01.013
Autor:
Hidetsugu Maekawa, Yoshiteru Tada, Kenji Yagi, Takeshi Miyamoto, Keiko T. Kitazato, Masaaki Korai, Junichiro Satomi, Tomoki Hashimoto, Shinji Nagahiro
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-8 (2017)
Abstract Background Estrogen deficiency is thought to be responsible for the higher frequency of aneurysmal subarachnoid hemorrhage in post- than premenopausal women. Estrogen replacement therapy appears to reduce this risk but is associated with sig
Externí odkaz:
https://doaj.org/article/9abdabae507a4e4b894f2d3445d18504
Publikováno v:
Stroke. 54
Background: Clinical studies consistently show a strong association between aging and increased risk of intracranial aneurysmal rupture. Aging causes the accumulation of senescent cells that promote chronic inflammation through the senescence-associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65b4cd4df22d4954c3c79163a31a19d2
https://doi.org/10.1161/str.54.suppl_1.wp224
https://doi.org/10.1161/str.54.suppl_1.wp224
Publikováno v:
Stroke. 54
Introduction: Aging is a known risk factor for intracranial aneurysm rupture in human clinical studies. However, clinical studies only showed the association, but not the causality of aging and aneurysm rupture. Using our well-established mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84be93e17aeddc0c934711e5cb601714
https://doi.org/10.1161/str.54.suppl_1.tp213
https://doi.org/10.1161/str.54.suppl_1.tp213