Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Tomokazu Watano"'
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 94:1-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77e04d7f50031bcc7e2a5ef57b102231
https://doi.org/10.1254/jpssuppl.94.0_1-o-c2-4
https://doi.org/10.1254/jpssuppl.94.0_1-o-c2-4
Publikováno v:
The Journal of Physiology. 558:745-757
The role of P2 receptors in synaptic transmission to the rat medial nucleus of the trapezoid body (MNTB) was studied in an in vitro brain slice preparation. Whole-cell patch recordings were made and spontaneous synaptic responses studied under voltag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16c929c86c55434eadb59797f5f62f75
https://doi.org/10.1113/jphysiol.2004.066845
https://doi.org/10.1113/jphysiol.2004.066845
Autor:
Yuji Imaizumi, Libing Li, Masamitsu Hinata, Yasuhide Watanabe, Tomokazu Watano, Hisao Yamamura, Junko Kimura
Publikováno v:
The Journal of Physiology. 545:453-461
In single guinea-pig ventricular myocytes, we examined the stoichiometry of Na+-Ca2+ exchange (NCX) by measuring the reversal potential (ENCX) of NCX current (INCX) and intracellular Ca2+ concentration ([Ca2+]i) with the whole-cell voltage-clamp tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4483a812111a19ac5873d06d1fb20ab5
https://doi.org/10.1113/jphysiol.2002.025866
https://doi.org/10.1113/jphysiol.2002.025866
Publikováno v:
Japanese Journal of Pharmacology. 88:428-435
ATP activates the mouse P2X7 receptor and induces a nonselective-cation current in NG108-15 cells. We investigated the effects of five receptor antagonists on the ATP-induced nonselective-cation current through P2X7 receptor (I(NS.P2X7)) in NG108-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78ae6be54be8de96bd128750dfe66ff
https://doi.org/10.1254/jjp.88.428
https://doi.org/10.1254/jjp.88.428
Autor:
Satoko Ohkubo, Junko Kimura, Takahiro Iwamoto, Munekazu Shigekawa, Tomokazu Watano, Yasuhide Watanabe, Tomoyuki Ono, Isao Matsuoka
Publikováno v:
British Journal of Pharmacology. 132:1317-1325
1. The effect of 2,3-butanedione monoxime (BDM), a 'chemical phosphatase', on Na(+)/Ca(2+) exchange current (I(NCX)) was investigated using the whole-cell voltage-clamp technique in single guinea-pig cardiac ventricular myocytes and in CCL39 fibrobla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b91ee5858e052fe8edebee637da38e6
https://doi.org/10.1038/sj.bjp.0703926
https://doi.org/10.1038/sj.bjp.0703926
Publikováno v:
British Journal of Pharmacology. 128:969-974
We investigated the inhibitory effect of KB-R7943 on ‘bi-directional' Na+/Ca2+ exchange current (iNCX) with the reversal potential of iNCX (ENCX) in the middle of the ramp voltage pulse employed. Bi-directional iNCX was recorded with ‘full' ramp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d6c64378f1af658a41827d7adb2a5eb
https://doi.org/10.1038/sj.bjp.0702869
https://doi.org/10.1038/sj.bjp.0702869
Publikováno v:
British Journal of Pharmacology. 127:1846-1850
We investigated protective effects of KB-R7943, a Na+/Ca2+ exchange (NCX) inhibitor, on ouabain-induced tonotropy and arrhythmias in isolated whole atria and ouabain-induced changes in electrocardiogram (ECG) in the guinea-pig. KB-R7943 (10 and 30 μ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e56eb40ab9c39a33689b465387d67ae
https://doi.org/10.1038/sj.bjp.0702740
https://doi.org/10.1038/sj.bjp.0702740
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 268:223-229
Effects of adenosine on inward current activated by extracellular ATP were examined in rat pheochromocytoma PC12 cells. Adenosine induced two types of modulation on the current activated by 30 microM ATP; a low concentration of adenosine (1 microM) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711067db8feccc84f8d43b3b4da160f1
https://doi.org/10.1016/0922-4106(94)90192-9
https://doi.org/10.1016/0922-4106(94)90192-9
Autor:
Tomokazu Watano, Partomuan Simanjuntak, Isao Kitagawa, Satoshi Fujii, Yuriko Yamagata, Motomasa Kobayashi, Hirotaka Shibuya
Publikováno v:
Chemical and Pharmaceutical Bulletin. 42:1798-1802
Five new cassane-type furanoditerpenes named caesaldekarins a (1), b (2), c, d, and e were isolated from the roots of Caesalpinia major (Fabaceae), an Indonesian medicinal plant. The chemical structures of 1 and 2 have been elucidated on the bases of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a015175039031206d79c168f2da462d
https://doi.org/10.1248/cpb.42.1798
https://doi.org/10.1248/cpb.42.1798
Autor:
Kazuhide Inoue, Ken Nakazawa, Tomokazu Watano, Akira Takanaka, Tomoko Obama, Kannosuke Fujimori, Mayumi Mori
Publikováno v:
Japanese Journal of Pharmacology. 61:351-356
Effects of hirsuteine, an indole alkaloid extracted from Uncaria genus, on nicotine and high K-induced responses were investigated in rat pheochromocytoma PC12 cells. Hirsuteine (300 nM-10 μM)inhibited dopamine release evoked by 100 μM nicotine in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54502ab2bc0325afd839adb93c4ecd31
https://doi.org/10.1254/jjp.61.351
https://doi.org/10.1254/jjp.61.351