Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Tomokazu Amano"'
Autor:
Cecily Choy, Joseph Chen, Jiangyuan Li, D. Travis Gallagher, Jian Lu, Daichao Wu, Ainslee Zou, Humza Hemani, Beverly A. Baptiste, Emily Wichmann, Qian Yang, Jeffrey Ciffelo, Rui Yin, Julia McKelvy, Denise Melvin, Tonya Wallace, Christopher Dunn, Cuong Nguyen, Chee W. Chia, Jinshui Fan, Jeannie Ruffolo, Linda Zukley, Guixin Shi, Tomokazu Amano, Yang An, Osorio Meirelles, Wells W. Wu, Chao-Kai Chou, Rong-Fong Shen, Richard A. Willis, Minoru S. H. Ko, Yu-Tsueng Liu, Supriyo De, Brian G. Pierce, Luigi Ferrucci, Josephine Egan, Roy Mariuzza, Nan-Ping Weng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The resolution of SARS-CoV-2 replication hinges on cell-mediated immunity, wherein CD8+ T cells play a vital role. Nonetheless, the characterization of the specificity and TCR composition of CD8+ T cells targeting non-spike protein of SARS-C
Externí odkaz:
https://doaj.org/article/963224e732b44fa8b3d0805dabc27063
Autor:
Tomokazu Amano, Hong Yu, Misa Amano, Erica Leyder, Maria Badiola, Priyanka Ray, Jiyoung Kim, Akihiro C. Ko, Achouak Achour, Nan-ping Weng, Efrat Kochba, Yotam Levin, Minoru S.H. Ko
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106335- (2023)
Summary: Intradermal delivery of self-replicating RNA (srRNA) is a promising vaccine platform. We have developed an srRNA that functions optimally at around 33°C (skin temperature) and is inactivated at or above 37°C (core body temperature) as a sa
Externí odkaz:
https://doaj.org/article/fa255e28e990463ca769c8009c863bfa
Autor:
Takenao Koseki, Mayumi Teramachi, Minako Koga, Minoru S. H. Ko, Tomokazu Amano, Hong Yu, Misa Amano, Erica Leyder, Maria Badiola, Priyanka Ray, Jiyoung Kim, Akihiro C. Ko, Achouak Achour, Nan-ping Weng, Takumi Imai, Hisako Yoshida, Satsuki Taniuchi, Ayumi Shintani, Hidetsugu Fujigaki, Masashi Kondo, Yohei Doi
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1767 (2023)
mRNA vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have played a key role in reducing morbidity and mortality from coronavirus disease 2019 (COVID-19). We conducted a double-blind, placebo-controlled phase I/II trial t
Externí odkaz:
https://doaj.org/article/18beafabbfdd4081a2b1ad576923e462
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106916 (2014)
The ability of small molecules to maintain self-renewal and to inhibit differentiation of pluripotent stem cells has been well-demonstrated. Two widely used molecules are PD 98059 (PD), an inhibitor of extracellular-signal-regulated kinase 1 (ERK), a
Externí odkaz:
https://doaj.org/article/df9a8b96091543249a5de2f5c2648eab
Autor:
Kazuo Tonami, Shoji Hata, Koichi Ojima, Yasuko Ono, Yukiko Kurihara, Tomokazu Amano, Takahiro Sato, Yumiko Kawamura, Hiroki Kurihara, Hiroyuki Sorimachi
Publikováno v:
PLoS Genetics, Vol 9, Iss 8, p e1003668 (2013)
Calpains are Ca(2+)-dependent modulator Cys proteases that have a variety of functions in almost all eukaryotes. There are more than 10 well-conserved mammalian calpains, among which eutherian calpain-6 (CAPN6) is unique in that it has amino acid sub
Externí odkaz:
https://doaj.org/article/7744e534724b4e34bb3cd6699b0ae150
Autor:
Kasiani Myers, Stella M. Davies, Carolyn M. Lutzko, Robin Wahle, Geraldine Aubert, Tomokazu Amano, Misa Amano, Hong Yu, Minoru S.H. Ko
Publikováno v:
Transplantation and Cellular Therapy. 29:S224-S225
Autor:
Kasiani C. Myers, Stella M Davies, Carolyn Lutzko, Robin Wahle, Geraldine Aubert, Tomokazu Amano, Misa Amano, Hong Yu, Minoru S.H. Ko
Publikováno v:
Blood. 140:1895-1896
Publikováno v:
DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
Aneuploidy, an abnormal number of chromosomes, has previously been considered irremediable. Here, we report findings that euploid cells increased among cultured aneuploid cells after exposure to the protein ZSCAN4, encoded by a mammalian-specific gen
Autor:
Ie Ming Shih, Minoru Sh Ko, Blanca L. Valle, Yoshihiko Araki, Tomokazu Amano, Tian Li Wang, Kevin G. Becker, Robert J. Kurman, Ichiro Miyoshi, Yongqing Zhang, Cheryl A. Sherman-Baust, Patrice J. Morin, Elin Lehrmann, Elisabetta Kuhn
Publikováno v:
The Journal of Pathology. 233:228-237
Recent evidence suggests that ovarian high-grade serous carcinoma (HGSC) originates from the epithelium of the fallopian tube. However, most mouse models are based on the previous prevailing view that ovarian cancer develops from the transformation o
Autor:
Carole A. Stagg, Yulan Piao, Yong Qian, Lioudmila V. Sharova, Minoru S.H. Ko, Dawood B. Dudekula, Alexei A. Sharov, Tomokazu Amano, David Schlessinger
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 52(5)
Retinoic acid (RA) is one of the most potent inducers of differentiation of mouse embryonic stem cells (ESCs). However, previous studies show that RA treatment of cells cultured in the presence of a leukemia inhibitory factor (LIF) also result in the