Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Tomokazu, Kawaoka"'
Autor:
Masanari Kosaka, Hatsue Fujino, Masataka Tsuge, Shinsuke Uchikawa, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki, C. Nelson Hayes, Shiro Oka
Publikováno v:
Livers, Vol 4, Iss 3, Pp 364-376 (2024)
The preS1 region of the large hepatitis B virus (HBV) surface protein is a crucial component in HBV infection; however, its impact on the development of hepatocellular carcinoma (HCC) remains unknown. This study investigated the relationship between
Externí odkaz:
https://doaj.org/article/281f1728ddd34a2eb174c618f49f5d04
Autor:
Yuko Nagaoki, Kenji Yamaoka, Yasutoshi Fujii, Shinsuke Uchikawa, Hatsue Fujino, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki, Hiroshi Aikata, C. Nelson Hayes, Masataka Tsuge, Shiro Oka
Publikováno v:
Livers, Vol 4, Iss 3, Pp 352-363 (2024)
To clarify the risk factors for the aggravation of esophagogastric varices (EGVs) after hepatitis C virus (HCV) eradication with direct-acting antiviral (DAA) therapy, we enrolled 167 consecutive patients with HCV-related compensated cirrhosis who ac
Externí odkaz:
https://doaj.org/article/9561c7e746144a2781c2f6ff47ab51b5
Autor:
Huarui Bao, Serami Murakami, Masataka Tsuge, Takuro Uchida, Shinsuke Uchikawa, Hatsue Fujino, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki, Clair Nelson Hayes, Shiro Oka
Publikováno v:
Viruses, Vol 16, Iss 11, p 1743 (2024)
Cross-sectional analyses using liver tissue from chronic hepatitis B patients make it difficult to exclude the influence of host immune responses. In this study, we performed next-generation sequencing using the livers of hepatitis B virus (HBV)-infe
Externí odkaz:
https://doaj.org/article/db9d4583c1d0406e82acc1a95c231483
Autor:
Takahiro Kinami, Shinsuke Uchikawa, Tomokazu Kawaoka, Shintaro Yamasaki, Masanari Kosaka, Yusuke Johira, Shigeki Yano, Kei Amioka, Kensuke Naruto, Kenji Yamaoka, Yasutoshi Fujii, Hatsue Fujino, Takashi Nakahara, Atsushi Ono, Eisuke Murakami, Wataru Okamoto, Masami Yamauchi, Daiki Miki, Masataka Tsuge, Shiro Oka
Publikováno v:
Cancer Medicine, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Aim Atezolizumab plus bevacizumab combination therapy (Atezo + Beva) is used as the first‐line therapy for unresectable hepatocellular carcinoma (u‐HCC). Serious adverse events (AEs), including rupture of esophagogastric varices, have be
Externí odkaz:
https://doaj.org/article/750b5eb5b5f54de5bfbf22b2506451a0
Autor:
Masami Yamauchi, Atsushi Ono, Kei Amioka, Yasutoshi Fujii, Hikaru Nakahara, Yuji Teraoka, Shinsuke Uchikawa, Hatsue Fujino, Takashi Nakahara, Eisuke Murakami, Wataru Okamoto, Daiki Miki, Tomokazu Kawaoka, Masataka Tsuge, Michio Imamura, C. Nelson Hayes, Waka Ohishi, Takeshi Kishi, Mizuki Kimura, Natsumi Suzuki, Koji Arihiro, Hiroshi Aikata, Kazuaki Chayama, Shiro Oka
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-14 (2023)
Abstract Background Lenvatinib, a multiple receptor tyrosine kinase inhibitor, might exert antitumor effects via tumor immune modulation. However, changes in the tumor immune microenvironment induced by lenvatinib are poorly understood. We investigat
Externí odkaz:
https://doaj.org/article/ba99e570f9db4c279b4af8e694a6a536
Autor:
Yusuke Johira, Takashi Nakahara, Takahiro Kinami, Shintaro Yamasaki, Masanari Kosaka, Yuki Shirane, Ryoichi Miura, Serami Murakami, Shigeki Yano, Kei Amioka, Kensuke Naruto, Yuwa Ando, Yumi Kosaka, Kenichiro Kodama, Shinsuke Uchikawa, Hatsue Fujino, Atsushi Ono, Eisuke Murakami, Wataru Okamoto, Masami Yamauchi, Tomokazu Kawaoka, C. Nelson Hayes, Masataka Tsuge, Michio Imamura, Hiroshi Aikata, Shiro Oka
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Metabolic dysfunction-associated fatty liver disease (MAFLD) represents a new classification system for fatty liver disease. In this study, we investigated the clinical characteristics of patients with MAFLD-hepatocellular carcino
Externí odkaz:
https://doaj.org/article/571494618e314b039648ca2219373de7
Autor:
Issei Saeki, Takahiro Yamasaki, Yurika Yamauchi, Tomokazu Kawaoka, Shinsuke Uchikawa, Akira Hiramatsu, Hiroshi Aikata, Kazufumi Kobayashi, Takayuki Kondo, Sadahisa Ogasawara, Tetsuhiro Chiba, Reo Kawano, Kazuaki Chayama, Naoya Kato, Taro Takami
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10625-10635 (2023)
Abstract Aim Skeletal muscle volume has been reported to be an important factor that determines overall survival (OS) and post‐progression survival (PPS) in patients with hepatocellular carcinoma (HCC). However, the impact of skeletal muscle volume
Externí odkaz:
https://doaj.org/article/264ad3bdf8c3415999ff96b985e4fa87
Autor:
Hiroshi Sakai, Masataka Tsuge, Masahiro Ohira, Tsuyoshi Kobayashi, Ryosuke Nakano, Shintaro Kuroda, Hiroyuki Tahara, Hideki Ohdan, Ko Oshita, Yosuke Namba, Sotaro Fukuhara, Keiso Matsubara, Daisuke Takei, Tomokazu Kawaoka, Naruhiko Honmyo, Keigo Chosa, Kazuo Awai
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction Small liver tumours are difficult to identify during hepatectomy, which prevents curative tumour excision. Preoperative marking is a standard practice for small, deep-seated tumours in other solid organs; however, its effectiveness for l
Externí odkaz:
https://doaj.org/article/6187910703b340bc86daafe720022c6b
Autor:
Hiroshi Aikata, Hiroshi Sakai, Michio Imamura, Masahiro Ohira, Tsuyoshi Kobayashi, Ryosuke Nakano, Naoki Tanimine, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Hideki Ohdan, Ko Oshita, Yosuke Namba, Sotaro Fukuhara, Keiso Matsubara, Daisuke Takei, Wataru Okamoto, Takashi Nakahara, Tomokazu Kawaoka
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction The feasibility and efficacy of surgical resection following systemic therapy for intermediate-stage hepatocellular carcinoma (HCC) beyond the Up-to-7 criteria is unclear. The combination of lenvatinib (LEN) and transcatheter arterial ch
Externí odkaz:
https://doaj.org/article/eb59f77ebb344eaabb71a7fdcf6d3d58
Autor:
Yuki Shirane, Eisuke Murakami, Michio Imamura, Masanari Kosaka, Yusuke Johira, Ryoichi Miura, Serami Murakami, Shigeki Yano, Kei Amioka, Kensuke Naruto, Yuwa Ando, Shinsuke Uchikawa, Yuji Teraoka, Takuro Uchida, Hatsue Fujino, Atsushi Ono, Takashi Nakahara, Tomokazu Kawaoka, Daiki Miki, Masami Yamauchi, Wataru Okamoto, Masataka Tsuge, Keigo Chosa, Kazuo Awai, Hiroshi Aikata, Shiro Oka
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Balloon-occluded retrograde transvenous obliteration (BRTO) is a treatment option for patients with gastric varices (GVs). This study aimed to clarify the clinical significance of portal hypertension estimated by the hepatic venou
Externí odkaz:
https://doaj.org/article/5a5eb080581442ad9a005702ca2d87f1