Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tomoka Mineyama"'
Autor:
Tetsuya Kubota, Mariko Inoue, Naoto Kubota, Iseki Takamoto, Tomoka Mineyama, Kaito Iwayama, Kumpei Tokuyama, Masao Moroi, Kohjiro Ueki, Toshimasa Yamauchi, Takashi Kadowaki
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Obesity is associated with low-grade chronic inflammation. Here the authors show that the activation of anti-inflammatory M2a-subtype macrophages requires the IL4/Irs2/Akt pathway. Due to decreased Irs2 expression this pathway is impaired in obese mi
Externí odkaz:
https://doaj.org/article/5c16b774daf24a59904c928896c9f12b
Autor:
Shun Saita, Masato Odawara, Yukio Shimasaki, Koichi Kisanuki, Nobuhiro Nishigaki, Ryo Suzuki, Tomoka Mineyama
Publikováno v:
Diabetes Therapy
Introduction To identify factors associated with treatment adherence and satisfaction in patients with type 2 diabetes (T2DM) in Japan. Methods A web-based questionnaire survey was conducted from 6 to 17 March 2019 in patients with T2DM aged ≥ 20 y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8f611f32c96cb22a0b4d863dda4f04
https://doi.org/10.1007/s13300-021-01100-3
https://doi.org/10.1007/s13300-021-01100-3
Autor:
Kaito Iwayama, Kohjiro Ueki, Kumpei Tokuyama, Tomoka Mineyama, Mariko Inoue, Iseki Takamoto, Takashi Kadowaki, Masao Moroi, Tetsuya Kubota, Toshimasa Yamauchi, Naoto Kubota
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
M2a-subtype macrophage activation is known to be impaired in obesity, although the underlying mechanisms remain poorly understood. Herein, we demonstrate that, the IL-4/Irs2/Akt pathway is selectively impaired, along with decreased macrophage Irs2 ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198038f6d7f0d0387a1adccae5be07d7
http://europepmc.org/articles/PMC6242852
http://europepmc.org/articles/PMC6242852
Autor:
Tomoka Mineyama, Toshifumi Hibi, Kosuke Iwasaki, Eri Udagawa, Akihito Uda, Wentao Tang, Taku Kobayashi
Publikováno v:
Gastroenterology. 154:S-361
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f5f80584f3b4c60c20b97026cd60f5d
https://doi.org/10.1016/s0016-5085(18)31524-5
https://doi.org/10.1016/s0016-5085(18)31524-5
Autor:
Hitomi Ogata, Takashi Kadowaki, Shin Ohnishi, Mitsuru Ohsugi, Kazuyuki Tobe, Kaoru Sugi, Masao Moroi, Iseki Takamoto, Shigeru Kakuta, Shinsuke Itoh, Tetsuya Kubota, Yasuo Terauchi, Hideki Kozono, Tetsuo Noda, Kohjiro Ueki, Takayoshi Sasako, Kumpei Tokuyama, Tomoka Mineyama, Hiroki Kumagai, Ryozo Nagai, Naoto Kubota, Yoichiro Iwakura
Publikováno v:
Cell Metabolism. 8:49-64
SummaryInsulin receptor substrate (Irs) mediates metabolic actions of insulin. Here, we show that hepatic Irs1 and Irs2 function in a distinct manner in the regulation of glucose homeostasis. The PI3K activity associated with Irs2 began to increase d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021d14b4be432588bb4e823ce2fbca3e
https://doi.org/10.1016/j.cmet.2008.05.007
https://doi.org/10.1016/j.cmet.2008.05.007
Autor:
Tomoka Mineyama, Mitsuhiko Noda
Publikováno v:
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics. 50(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715150524f725a4ed789c6dcdbf0ea4d
https://pubmed.ncbi.nlm.nih.gov/24622215
https://pubmed.ncbi.nlm.nih.gov/24622215
Autor:
Ritsuko Yamamoto-Honda, Mitsuhiko Noda, Shuichi Mishima, Hidekatsu Yanai, Osamu Ezaki, Masafumi Kakei, Hidetaka Hamasaki, Tomoka Mineyama
Publikováno v:
Diabetology & Metabolic Syndrome
Background Non-exercise activity thermogenesis (NEAT) is the energy expenditure due to physical activities besides active sports-like exercise and resistance training in daily life. Methods We studied 45 subjects (22 women and 23 men) with type 2 dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befa8c23a0d941cd1346eec75f87541b
https://pubmed.ncbi.nlm.nih.gov/23711224
https://pubmed.ncbi.nlm.nih.gov/23711224
Autor:
Tomoka, Mineyama, Mitsuhiko, Noda
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::978993b15f90366b15e03be5f98e657d
https://pubmed.ncbi.nlm.nih.gov/23156451
https://pubmed.ncbi.nlm.nih.gov/23156451
Autor:
Kohjiro Ueki, Masao Moroi, Kazuyuki Tobe, Tetsuo Noda, Hitomi Ogata, Hiroki Kumagai, Shinsuke Itoh, Hidemi Satoh, Michiro Ishikawa, Yasuo Terauchi, Toshimasa Yamauchi, Ryozo Nagai, Iseki Takamoto, Kumpei Tokuyama, Naoto Kubota, Tomoka Mineyama, Wataru Yano, Kaoru Sugi, Takashi Kadowaki, Tetsuya Kubota
Publikováno v:
The Journal of biological chemistry. 281(13)
Thiazolidinediones have been shown to up-regulate adiponectin expression in white adipose tissue and plasma adiponectin levels, and these up-regulations have been proposed to be a major mechanism of the thiazolidinedione-induced amelioration of insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5f3e9fc50252ec0c274ac3a4cd4810
https://pubmed.ncbi.nlm.nih.gov/16431926
https://pubmed.ncbi.nlm.nih.gov/16431926
Autor:
Yukiko, Kishi, Masahiro, Kami, Eiji, Kusumi, Tomoka, Mineyama, Daisuke, Kato, Tamae, Hamaki, Jun-ichi, Ueyama, Shigesaburo, Miyakoshi, Shin-ichi, Morinaga, Yoshitomo, Muto, Shuichi, Taniguchi
Publikováno v:
Haematologica. 89(5)
Intravascular large B-cell lymphoma (IVL) has been treated as fever of unknown origin (FUO), and many patients have been treated inadequately based on incorrect diagnoses. We previously cares for a patient with IVL who tested positive for prostatic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff4f9e9a6835c18796d372b3cf64a0c9
https://pubmed.ncbi.nlm.nih.gov/15136242
https://pubmed.ncbi.nlm.nih.gov/15136242