Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tomoka Ao"'
Autor:
Maki Uenaka, Erika Yamashita, Junichi Kikuta, Akito Morimoto, Tomoka Ao, Hiroki Mizuno, Masayuki Furuya, Tetsuo Hasegawa, Hiroyuki Tsukazaki, Takao Sudo, Keizo Nishikawa, Daisuke Okuzaki, Daisuke Motooka, Nobuyoshi Kosaka, Fuminori Sugihara, Thomas Boettger, Thomas Braun, Takahiro Ochiya, Masaru Ishii
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Bone remodeling involves a switch between bone formation and resorption, but the mechanisms is unclear. Here, the authors show that intercellular communication via extracellular vesicles secreted by mature osteoblasts is a key factor for the switchin
Externí odkaz:
https://doaj.org/article/084b29b141f748d4b865d9342d2c67eb
Autor:
Shino Nishizawa, Junichi Kikuta, Shigeto Seno, Masahiro Kajiki, Ryuichi Tsujita, Hiroki Mizuno, Takao Sudo, Tomoka Ao, Hideo Matsuda, Masaru Ishii
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 1, Pp 17-22 (2020)
Thrombomodulin (TM) is an integral membrane protein expressed on the surface of vascular endothelial cells that suppresses blood coagulation. Recent studies have shown that TM exhibits anti-inflammatory effects by inhibiting leukocyte recruitment. Ho
Externí odkaz:
https://doaj.org/article/885709cb2ec245a18c7e3e2a195d3b69
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1624 (2021)
Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin D receptor and 1α-hydroxylase. In vitro studies have shown that 1,25-dihydroxyvitamin D, the active form of vitamin D, has an anti-inflammatory effect. Rece
Externí odkaz:
https://doaj.org/article/b78c43dc8ced4bbb824ad39b769cad85
Publikováno v:
International immunology. 32(11):727-736
This is a pre-copyedited, author-produced version of an article accepted for publication in International Immunology following peer review. The version of record Tomoka Ao, Junichi Kikuta, Takao Sudo, Yutaka Uchida, Kenta Kobayashi, Masaru Ishii, Loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebc84d680da16944fef111382a8205e
https://hdl.handle.net/11094/78250
https://hdl.handle.net/11094/78250
Autor:
Akito Morimoto, Chie Fukuda, Hiroyuki Tsukazaki, Masaru Ishii, Takashi Kaito, Kazuya Kikuchi, Tomoka Ao, Masafumi Minoshima, Eisuke Tsuda, Junichi Kikuta
Publikováno v:
Bone. 152
Anti-resorptive drugs are widely used for the treatment of osteoporosis, but excessive inhibition of osteoclastogenesis can suppress bone turnover and cause the deterioration of bone quality. Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ad490f8b8ec534df9e550f22446078
https://pubmed.ncbi.nlm.nih.gov/34216837
https://pubmed.ncbi.nlm.nih.gov/34216837
Autor:
Maki Uenaka, Erika Yamashita, Junichi Kikuta, Akito Morimoto, Tomoka Ao, Hiroki Mizuno, Masayuki Furuya, Tetsuo Hasegawa, Hiroyuki Tsukazaki, Takao Sudo, Keizo Nishikawa, Daisuke Okuzaki, Daisuke Motooka, Nobuyoshi Kosaka, Fuminori Sugihara, Thomas Boettger, Thomas Braun, Takahiro Ochiya, Masaru Ishii
Publikováno v:
Nature communications. 13(1)
Bone metabolism is regulated by the cooperative activity between bone-forming osteoblasts and bone-resorbing osteoclasts. However, the mechanisms mediating the switch between the osteoblastic and osteoclastic phases have not been fully elucidated. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190455b423d3aa7910bb957cb2f053cf
https://pubmed.ncbi.nlm.nih.gov/35210428
https://pubmed.ncbi.nlm.nih.gov/35210428
Autor:
Junichi Kikuta, Masaru Ishii, Yuzuru Kanakura, Ryosuke Yoshizawa, Takashi Nagasawa, Tetsuo Hasegawa, Yasutaka Motomura, Hiroki Mizuno, Tomoka Ao, Daisuke Okuzaki, Kazuyo Moro, Takao Sudo, Takafumi Yokota, Takahiro Matsui, Daisuke Motooka
Publikováno v:
The Journal of Experimental Medicine
Sudo et al. demonstrate that group 2 innate lymphoid cells (ILC2s) in the bone marrow become activated following chemotherapy-induced stress and support hematopoietic recovery by producing GM-CSF. Adoptive transfer of ILC2s has therapeutic potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023b889a6e9f089c529908be041f646f
https://pubmed.ncbi.nlm.nih.gov/33666647
https://pubmed.ncbi.nlm.nih.gov/33666647
Publikováno v:
Biomolecules, Vol 11, Iss 1624, p 1624 (2021)
Biomolecules
Biomolecules
Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin D receptor and 1α-hydroxylase. In vitro studies have shown that 1,25-dihydroxyvitamin D, the active form of vitamin D, has an anti-inflammatory effect. Rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebda3eba1fe521e76b12d5a169baece
https://doi.org/10.3390/biom11111624
https://doi.org/10.3390/biom11111624
Autor:
Masaru Ishii, Hiroki Mizuno, Masahiro Kajiki, Ryuichi Tsujita, Junichi Kikuta, Shino Nishizawa, Takao Sudo, Shigeto Seno, Tomoka Ao, Hideo Matsuda
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 1, Pp 17-22 (2020)
Thrombomodulin (TM) is an integral membrane protein expressed on the surface of vascular endothelial cells that suppresses blood coagulation. Recent studies have shown that TM exhibits anti-inflammatory effects by inhibiting leukocyte recruitment. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c47345a910089a18c0e95dda46626f8
https://pubmed.ncbi.nlm.nih.gov/32122774
https://pubmed.ncbi.nlm.nih.gov/32122774
Autor:
Tadatsugu Taniguchi, Junko Nishio, Tatsuhiko Kodama, Hideyuki Yanai, Yoshitaka Kimura, Tomoka Ao, Sho Hangai, Kosuke Matsuki, Hideo Negishi, Takeshi Kawamura
Publikováno v:
Proceedings of the National Academy of Sciences. 113:3844-3849
Cellular components released into the external milieu as a result of cell death and sensed by the body are generally termed damage-associated molecular patterns (DAMPs). Although DAMPs are conventionally thought to be protective to the host by evokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28db85dcc86de29f0917ca78d52b14d2
https://doi.org/10.1073/pnas.1602023113
https://doi.org/10.1073/pnas.1602023113