Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tomoji Kocha"'
Autor:
Tomoji Kocha, Kazuo Suzuki, Akihiro Kojima, Mitsune Yamaguchi, Fukuda Teruo, Toshihiko Nagasawa, Takaaki Aoyagi, Yoshihiro Arimura
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 24:157-165
Activities of various enzymes including elastase were determined in sera from healthy control and from patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), IgA nephropathy (IgA NP), and other renal failures. In IgA NP, the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08752c1f067118e1a098c8e9db08a491
https://doi.org/10.3164/jcbn.24.157
https://doi.org/10.3164/jcbn.24.157
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 61:1603-1606
We studied the effects of benadrostin, an inhibitor of poly (ADP-ribose) polymerase, on apoptosis of HL-60 cells induced by 5-azacytidine. Benadrostin interfered with the apoptosis and inhibited the cell death in a dose- and time-dependent manner.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43e809dbc9a4df8965622d5673cfb1c7
https://doi.org/10.1271/bbb.61.1603
https://doi.org/10.1271/bbb.61.1603
Publikováno v:
Chemical and Pharmaceutical Bulletin. 38:3400-3406
Lactate dehydrogenase (LDH) was purified from rat and bovine tissues by affinity chromatography on immobilized colchicine and used for the separation of isoenzymes by high-performance anion-exchange liquid chromatography (HPLC). This analysis showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60db6675b29caf7feb27902f4728171
https://doi.org/10.1248/cpb.38.3400
https://doi.org/10.1248/cpb.38.3400
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 61:1027-1029
Humulone, a bone resorption inhibitor isolated from hop extract, induced apoptosis in the premyocytic leukemia cell line HL-60 between 1 and 100 micrograms/ml. Our data suggested that there was a correlation between the apoptosis-inducing activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8618336cba2d458d79863526fafc8eb1
https://doi.org/10.1271/bbb.61.1027
https://doi.org/10.1271/bbb.61.1027
Publikováno v:
Biochimica et biophysica acta. 1337(2)
Cupric ions (Cu2+) added to hydrogen peroxide (H2O2) were found to generate hydroxyl radicals (HO) capable of benzoate hydroxylation. Although ferrous (Fe2+) and ferric (Fe3+) ions, when added to H2O2, resulted in very little production of HO, the ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dab18d73e046ff4259c1e227d6c01a4
https://pubmed.ncbi.nlm.nih.gov/9048910
https://pubmed.ncbi.nlm.nih.gov/9048910
Autor:
Tomio Takeuchi, Tomoji Kocha, Hirokazu Ohtaki, Etsuko Ohtsuka, Yasuko Nonaka, Fukuda Teruo, Takaaki Aoyagi
Publikováno v:
Journal of enzyme inhibition. 10(1)
Ebelactones A and B, natural products from Streptomyces aburaviensis are potent inhibitors of pancreatic lipase. Lipase is the key enzyme required for the absorption of dietary triglycerides (TG). Ebelactone B inhibited, in a dose-dependent manner, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703262fd129cf3e3671985c837f70835
https://pubmed.ncbi.nlm.nih.gov/8835930
https://pubmed.ncbi.nlm.nih.gov/8835930
Publikováno v:
Biologicalpharmaceutical bulletin. 17(8)
It has been suggested that the activities of type IV collagenase and/or ectopeptidases possessed by malignant cells are related to their metastatic potentials. In the present study, we examined the activities of three aminopeptidases, two serine prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e892cd3a499e85e104effc7157e159
https://pubmed.ncbi.nlm.nih.gov/7820120
https://pubmed.ncbi.nlm.nih.gov/7820120
Publikováno v:
Journal of enzyme inhibition. 8(3)
The enzymatic changes in murine spleen caused by the administration for 20 successive days of various inhibitors of aminopeptidase N (leucocyte antigen CD13) have been compared. When compared with the control (saline), most of the inhibitors signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2004f5644aa8b7b5bfe6013eb4d43d7
https://pubmed.ncbi.nlm.nih.gov/7539487
https://pubmed.ncbi.nlm.nih.gov/7539487
Publikováno v:
Eisei kagaku. 27:175-178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7181840674524ce3dcd31d770ea7dbe4
https://doi.org/10.1248/jhs1956.27.175
https://doi.org/10.1248/jhs1956.27.175
Publikováno v:
Chemical and Pharmaceutical Bulletin. 34:3791-3802
Eleven immobilized-colchicine adsorbents were synthesized from deacetylcolchicine (DAC) and Sepharose with various spacers (R) and their tubulin-adsorbing capacity was investigated. The adsorption capacity of DAC-R-Sepharose for tubulin depended on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e4a0f5d29bff6e51ba26611c4dee97
https://doi.org/10.1248/cpb.34.3791
https://doi.org/10.1248/cpb.34.3791