Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Tomohito, Sato"'
Autor:
Masaru Takeuchi, Yoshiaki Nishio, Hideaki Someya, Tomohito Sato, Akihiko Yoshimura, Masataka Ito, Kozo Harimoto
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
PurposeInflammation is involved in the pathogenesis of diabetes, however the impact of diabetes on organ-specific autoimmune diseases remains unexplored. Experimental autoimmune uveoretinitis (EAU) is a widely accepted animal model of human endogenou
Externí odkaz:
https://doaj.org/article/0e9d3ea2fe8745e19f89699888440379
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9158 (2024)
Proliferative diabetic retinopathy (PDR) is a vision-threatening complication of diabetes mellitus (DM). Anterior chamber (AC) flare and intraocular cytokines are potent biomarkers reflecting the intraocular immune status in PDR. This study aimed to
Externí odkaz:
https://doaj.org/article/d988227a4a9a47c78c3b0059dd8c29d1
Publikováno v:
Vaccines, Vol 12, Iss 8, p 878 (2024)
The pandemic of COVID-19 caused by the SARS-CoV-2 virus is ongoing and a serious menace to global public health. An ocular manifestation is an initial sign of the infection. To date, a comprehensive immune profile of patients with mild COVID-19 has n
Externí odkaz:
https://doaj.org/article/34b7dcdb506b473c8d0347e9f63d580c
Autor:
Masaki Yoshioka, Tomoko Kaneko, Karen Yoneko, Masahiro Matsui, Shoya Mori, Natsumi Nishitani, Qin Wenxing, Kei Ouchi, Risa Yasuda, Hayate Namatame, Tomohito Sato, Jiyeon Park, Yoshio Nakata, Seiji Maeda, Keisei Kosaki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract This randomized controlled trial aimed to investigate the effects of eight weeks of lactotripeptide (LTP) ingestion, physical activity (PA) intervention, and combined intervention on the fatigue status of middle-aged and older adults. A tota
Externí odkaz:
https://doaj.org/article/7eea83d327924cc7b860c7941094530b
Autor:
Md Foyzur Rahman, Ariful Islam, Md. Monirul Islam, Md. Al Mamun, Lili Xu, Takumi Sakamoto, Tomohito Sato, Yutaka Takahashi, Tomoaki Kahyo, Satoka Aoyagi, Kozo Kaibuchi, Mitsutoshi Setou
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7969 (2024)
Mass spectrometry imaging (MSI) is essential for visualizing drug distribution, metabolites, and significant biomolecules in pharmacokinetic studies. This study mainly focuses on imipramine, a tricyclic antidepressant that affects endogenous metaboli
Externí odkaz:
https://doaj.org/article/f4c1e4d10e6f4edea990350cb8eb9acc
Autor:
Jing Yan, Tomoaki Kahyo, Hengsen Zhang, Yashuang Ping, Chi Zhang, Shuyun Jiang, Qianqing Ji, Rafia Ferdous, Md. Shoriful Islam, Soho Oyama, Shuhei Aramaki, Tomohito Sato, Mst. Afsana Mimi, Md. Mahmudul Hasan, Mitsutoshi Setou
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7353 (2024)
Aberrant aggregation of misfolded alpha-synuclein (α-syn), a major pathological hallmark of related neurodegenerative diseases such as Parkinson’s disease (PD), can translocate between cells. Ubiquitin-like 3 (UBL3) is a membrane-anchored ubiquiti
Externí odkaz:
https://doaj.org/article/d84e67a081cd4ced8c818efb59d42165
Autor:
Ryuta Muraki, Yoshifumi Morita, Shinya Ida, Ryo Kitajima, Satoru Furuhashi, Makoto Takeda, Hirotoshi Kikuchi, Yoshihiro Hiramatsu, Yusuke Takanashi, Yasushi Hamaya, Ken Sugimoto, Jun Ito, Kazuhito Kawata, Hideya Kawasaki, Tomohito Sato, Tomoaki Kahyo, Mitsutoshi Setou, Hiroya Takeuchi
Publikováno v:
Cancer Medicine, Vol 12, Iss 12, Pp 13007-13018 (2023)
Abstract Background Owing to the lack of definite diagnostic modalities, it is challenging to distinguish malignant cases of cholangiocarcinoma (CCA), which often causes biliary tract obstruction, from benign ones. Here, we investigated a novel lipid
Externí odkaz:
https://doaj.org/article/b93b3e59f1924026a113e27563dd7db0
Autor:
Md. Monirul Islam, Md Foyzur Rahman, Ariful Islam, Mst. Sayela Afroz, Md. Al Mamun, Md. Muedur Rahman, Md Maniruzzaman, Lili Xu, Takumi Sakamoto, Yutaka Takahashi, Tomohito Sato, Tomoaki Kahyo, Mitsutoshi Setou
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4840 (2024)
Knowledge of gender-specific drug distributions in different organs are of great importance for personalized medicine and reducing toxicity. However, such drug distributions have not been well studied. In this study, we investigated potential differe
Externí odkaz:
https://doaj.org/article/eba4480da56a462eaf855d4048fee3ab
Autor:
Yusuke Takanashi, Tomoaki Kahyo, Takamitsu Hayakawa, Keigo Sekihara, Akikazu Kawase, Minako Kondo, Takuya Kitamoto, Yutaka Takahashi, Tomohito Sato, Haruhiko Sugimura, Norihiko Shiiya, Mitsutoshi Setou, Kazuhito Funai
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Background The risk of postoperative recurrence is higher in lung cancer patients who smoke than non-smokers. However, objective evaluation of the postoperative recurrence risk is difficult using conventional pathological prognostic factors
Externí odkaz:
https://doaj.org/article/63916a4cf17b4a1289035f440ce18f37
Autor:
Sentaro Kusuhara, Masahiko Shimura, Shigehiko Kitano, Masahiko Sugimoto, Daisuke Muramatsu, Harumi Fukushima, Yoshihiro Takamura, Makiko Matsumoto, Masahide Kokado, Jiro Kogo, Mariko Sasaki, Yuki Morizane, Takuya Utsumi, Osamu Kotake, Takashi Koto, Hiroto Terasaki, Takao Hirano, Hiroto Ishikawa, Yoshinori Mitamura, Fumiki Okamoto, Takamasa Kinoshita, Kazuhiro Kimura, Kenji Yamashiro, Yukihiko Suzuki, Taiichi Hikichi, Noriaki Washio, Tomohito Sato, Kishiko Ohkoshi, Hiroki Tsujinaka, Mineo Kondo, Hitoshi Takagi, Toshinori Murata, Taiji Sakamoto, Japan Clinical Retina Study (J‐CREST) group
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 8, Pp 1339-1346 (2022)
ABSTRACT Aims/Introduction In older patients, the management of diabetic macular edema (DME) can be complicated by comorbidities, geriatric syndrome, and socioeconomic status. This study aims to evaluate the effects of aging on the management of DME.
Externí odkaz:
https://doaj.org/article/89b705ed028e4ecdb9df13da159a4d96