Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Tomohito, Kakegawa"'
Publikováno v:
Japanese Geotechnical Society Special Publication. 8:536-540
Autor:
Lucia Satiko Yoshida, Mariko Takada, Mari Noguchi, Tomohito Kakegawa, Ken Yasukawa, Hiromi Takano-Ohmuro
Publikováno v:
Journal of Natural Medicines. 73:190-201
We have proposed that analysis of ribosome-loaded mRNAs (i.e., the translatome) is useful for elucidation of pharmacological effects of phytocompounds in immune cells, regarding the involvement of post-transcriptional regulation mechanisms. In the pr
Publikováno v:
Journal of Natural Medicines. 70:653-660
We aimed to investigate the bioactive components of Alpinia japonica as anti-inflammatory compounds using searches of the Alpinia genus, and subsequently demonstrated that alpinone 3-acetate markedly inhibits 12-O-tetradecanoyiphorbol 13-acetate-indu
Autor:
Hirokazu Kawagishi, Hiromi Takano-Ohmuro, Lucia Satiko Yoshida, Yasukatsu Yuda, Naokazu Morishita, Kimiko Kazumura, Tomohito Kakegawa, Hiroshi Tsuchiya, Akiko Hara
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 59:1-9
Shikonin, an anti-inflammatory compound of "Shikon", inhibits the neutrophil superoxide (O2 (•-)) generation by NADPH oxidase 2 (Nox2); however, the mechanisms of how shikonin affects Nox2 activity remained unclear. We aimed to elucidate the relati
Autor:
Ken Yasukawa, Tomohito Kakegawa
Publikováno v:
Journal of Pharmacy and Nutrition Sciences. 5:216-221
Cancer prevention offers the most cost-effective long-term health strategy. The methanol extract of the leaves of guava ( Psidium guajava ) exhibits marked antitumor activity in an in vivo two-stage carcinogenesis test in mice using 7,12-dimethylbenz
Publikováno v:
Journal of natural medicines. 71(4)
We aimed to find candidate molecules possibly involved in the anti-inflammatory activity of shikonin (active compound of "Shikon") by analyzing its effects on gene expression of lipopolysaccharide (LPS)-treated THP-1 macrophages. Polysome-associated
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2014 (2014)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Diarylheptanoids (AO-0001, AO-0002, and AO-0003) isolated fromAlpinia officinaruminhibit proinflammatory mediators and exhibit cytotoxic and antiviral activity. However, the precise mechanisms of action of these diarylheptanoids are unknown as are th
Autor:
Shunji Kohri, Hiromi Takano-Ohmuro, Shohko Tsunawaki, Tomohito Kakegawa, Taizo Taniguchi, Lucia S. Yoshida, Hirotada Fujii
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
With the aim of developing effective anti-inflammatory drugs, we have been investigating the biochemical effects of shikonin of "Shikon" roots, which is a naphthoquinone with anti-inflammatory and antioxidative properties. Shikonin scavenged reactive
Autor:
Tomohito Kakegawa, Yasuhito Arai, Taichi Hyodo, Kazuyoshi Hashimoto, Yoshimichi Tsukamoto, Shohei Noda
Publikováno v:
Journal of Japan Society of Civil Engineers, Ser. B3 (Ocean Engineering). 75:I_211-I_216
Autor:
Kimiko, Kazumura, Lucia Satiko, Yoshida, Akiko, Hara, Hiroshi, Tsuchiya, Naokazu, Morishita, Hirokazu, Kawagishi, Tomohito, Kakegawa, Yasukatsu, Yuda, Hiromi, Takano-Ohmuro
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
Shikonin, an anti-inflammatory compound of "Shikon", inhibits the neutrophil superoxide (O2 (•-)) generation by NADPH oxidase 2 (Nox2); however, the mechanisms of how shikonin affects Nox2 activity remained unclear. We aimed to elucidate the relati