Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Tomohisa OKUNO"'
Autor:
Yurie Yamamoto, Go Masuda, Shuhei Kushiyama, Koji Maruo, Gen Tsujio, Tomohiro Sera, Atsushi Sugimoto, Sadaaki Nishimura, Kenji Kuroda, Shingo Togano, Tomohisa Okuno, Masaichi Ohira, Masakazu Yashiro
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 6016-6022 (2023)
Abstract Gastric cancer (GC) with microsatellite instability (MSI) has been reported to be sensitive to immunotherapy, however some of GC cases with MSI remain resistant to immunotherapy. Cancer cell lines showing MSI might be useful for the analysis
Externí odkaz:
https://doaj.org/article/582e1c23bcbc4b42ba87ecb036259a5f
Autor:
Shingo Togano, Masakazu Yashiro, Go Masuda, Atsushi Sugimoto, Yuichiro Miki, Yurie Yamamoto, Tomohiro Sera, Shuhei Kushiyama, Sadaaki Nishimura, Kenji Kuroda, Tomohisa Okuno, Masaichi Ohira
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Cancer stem cells (CSCs) play an important role in the progression of carcinoma and have a high potential for survival in stress environments. However, the mechanisms of survival potential of CSCs have been unclear. The aim of this study was
Externí odkaz:
https://doaj.org/article/e9fa03ba03de491cb89472001a4ae5e6
Autor:
Masakazu Yashiro, Kenji Kuroda, Go Masuda, Tomohisa Okuno, Yuichiro Miki, Yurie Yamamoto, Tomohiro Sera, Atsushi Sugimoto, Shuhei Kushiyama, Sadaaki Nishimura, Shingo Togano, Masaichi Ohira
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Fibroblast growth factor receptor 2 (FGFR2) has two isoforms: IIIb type and IIIc type. Clinicopathologic significance of these two FGFR2 subtypes in gastric cancer remains to be known. This study aimed to clarify the clinicopathologic differ
Externí odkaz:
https://doaj.org/article/57f653c36cdc4e4f86e8dfd190fdd59e
Autor:
Yuichiro Miki, Masakazu Yashiro, Kenji Kuroda, Tomohisa Okuno, Shingo Togano, Go Masuda, Hiroaki Kasashima, Masaichi Ohira
Publikováno v:
Cancer Medicine, Vol 10, Iss 2, Pp 521-528 (2021)
Abstract It has been reported that circulating tumor cells (CTCs) are beneficial for predicting tumor stage or treatment response. Although epithelial cell adhesion molecules (EpCAMs) and cytokeratin (CK) have been often used for the identification o
Externí odkaz:
https://doaj.org/article/195892381f7d495495a2ace6df380e57
Autor:
Atsushi Sugimoto, Tomohisa Okuno, Gen Tsujio, Tomohiro Sera, Yurie Yamamoto, Koji Maruo, Shuhei Kushiyama, Sadaaki Nishimura, Kenji Kuroda, Shingo Togano, Yuichiro Miki, Mami Yoshii, Tatsuro Tamura, Takahiro Toyokawa, Hiroaki Tanaka, Kazuya Muguruma, Masaichi Ohira, Masakazu Yashiro
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253702 (2021)
BackgroundGastric cancer (GC) patients frequently develop peritoneal metastasis. Recently, it has been reported that peritoneal mesothelial cells (PMCs) activated by GC cells acquire a migratory capacity and promote GC cell invasion. The invasiveness
Externí odkaz:
https://doaj.org/article/5d385b49bd7e405f97d770de9a3e32f8
Autor:
Shingo Togano, Masakazu Yashiro, Yuichiro Miki, Yurie Yamamoto, Tomohiro Sera, Yukako Kushitani, Atsushi Sugimoto, Shuhei Kushiyama, Sadaaki Nishimura, Kenji Kuroda, Tomohisa Okuno, Mami Yoshii, Tatsuro Tamura, Takahiro Toyokawa, Hiroaki Tanaka, Kazuya Muguruma, Sayaka Tanaka, Masaichi Ohira
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233743 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0225958.].
Externí odkaz:
https://doaj.org/article/800e6ca6c60640e980544138b8e2d250
Autor:
Shingo Togano, Masakazu Yashiro, Yuichiro Miki, Yurie Yamamoto, Tomohiro Sera, Yukako Kushitani, Atsushi Sugimoto, Shuhei Kushiyama, Sadaaki Nishimura, Kenji Kuroda, Tomohisa Okuno, Mami Yoshii, Tatsuro Tamura, Takahiro Toyokawa, Hiroaki Tanaka, Kazuya Muguruma, Sayaka Tanaka, Masaichi Ohira
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0225958 (2020)
BACKGROUND:Peritoneal recurrence is one of the most frequent recurrent diseases in gastric cancer. Although the exposure of cancer cells to the serosal surface is considered a common risk factor for peritoneal recurrence, there are some cases of peri
Externí odkaz:
https://doaj.org/article/f3c56ecf67bc49aa93048deaf107112e
Autor:
Kenji Kuroda, Masakazu Yashiro, Tomohiro Sera, Yurie Yamamoto, Yukako Kushitani, Atsushi Sugimoto, Syuhei Kushiyama, Sadaaki Nishimura, Shingo Togano, Tomohisa Okuno, Tatsuro Tamura, Takahiro Toyokawa, Hiroaki Tanaka, Kazuya Muguruma, Masaichi Ohira
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224727 (2019)
INTRODUCTION:Thrombospondin-4 [1] is an extracellular glycoprotein involved in wound healing and tissue remodeling. Although THBS4 is reportedly frequently expressed in solid tumors, there are few reports of the clinicopathological features of carcin
Externí odkaz:
https://doaj.org/article/0c82900566ca4889a804410f5c79554e
Autor:
Yuichiro Miki, Masakazu Yashiro, Tomohisa Okuno, Kenji Kuroda, Shingo Togano, Kosei Hirakawa, Masaichi Ohira
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202956 (2018)
BACKGROUND:It has been reported that CD63, an exosome marker, is expressed in solid cancer tissues. However, its significance in patients with gastric cancer has not been clarified. Exosomes derived from cancer cells and stromal cells might play an i
Externí odkaz:
https://doaj.org/article/6d84c8742d6f417dacfbe02d5257bb42
Autor:
Yurie Yamamoto, Go Masuda, Shuhei Kushiyama, Koji Maruo, Gen Tsujio, Tomohiro Sera, Atsushi Sugimoto, Sadaaki Nishimura, Kenji Kuroda, Shingo Togano, Tomohisa Okuno, Masaichi Ohira, Masakazu Yashiro
Publikováno v:
Cancer medicineREFERENCES.
Gastric cancer (GC) with microsatellite instability (MSI) has been reported to be sensitive to immunotherapy, however some of GC cases with MSI remain resistant to immunotherapy. Cancer cell lines showing MSI might be useful for the analysis of mecha