Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tomohisa Nishioka"'
Publikováno v:
Immunology letters. 121(2)
CD4(+)Foxp3(+) regulatory T cells (Treg cells) play an important role in maintaining self-tolerance as suppressive/regulatory CD4 T cells. In vitro analyses have revealed the characteristics of Treg cells, that is, hyporesponsiveness when stimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c92ca793166650d0c2cbd9842e94615
https://pubmed.ncbi.nlm.nih.gov/18930767
https://pubmed.ncbi.nlm.nih.gov/18930767
Publikováno v:
Immunology letters. 121(1)
Aging leads to a decline in the reactivity of CD4 T cells, in humans and mice. However, we have reported that not all CD4 T cells in aged mice were hyporesponsive, that is, a particular subset maintained the ability to mount a normal response. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c70502b430978b26086c1734c666d5
https://pubmed.ncbi.nlm.nih.gov/18718488
https://pubmed.ncbi.nlm.nih.gov/18718488
Autor:
Mitsuo Maruyama, Tomohisa Nishioka, Masataka Sugimoto, Junichi Shimada, Kunihiko Terauchi, Natsuko Uekawa, Satoshi Ohta
Publikováno v:
Hybridoma (2005). 26(6)
TARSH/Abi3bp was originally isolated as a novel target of NESH-SH3 by a two-hybrid yeast system. We have already identified murine TARSH (mTARSH) as a cellular senescence-related gene because of its robust induction in the early phase of mouse embryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bb142182eff4fedc8b3e83cbc2b432
https://pubmed.ncbi.nlm.nih.gov/18158782
https://pubmed.ncbi.nlm.nih.gov/18158782
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 176(11)
Aging is associated with a progressive decline in T cell-mediated immune responses. However, it has been unknown whether regulatory/suppressive CD4 T cells are involved in this decline. Our in vitro analyses revealed that CD4+CD25+ T cells, the well-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99442dd626e666f2d00ffd45879a6ff4
https://pubmed.ncbi.nlm.nih.gov/16709816
https://pubmed.ncbi.nlm.nih.gov/16709816
Autor:
Shimon Sakaguchi, Tomohisa Nishioka, Miyuki Azuma, Isao Ishikawa, Pornpan Youngnak, Fumiko Kanamaru, Takeshi Takahashi, Masaaki Hashiguchi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 172(12)
The glucocorticoid-induced TNF receptor (GITR), which is a member of the TNF receptor family, is expressed preferentially at high levels on CD25+CD4+ regulatory T cells and plays a key role in the peripheral tolerance that is mediated by these cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f95bab51f23aa03be4c97e86889bd3
https://pubmed.ncbi.nlm.nih.gov/15187106
https://pubmed.ncbi.nlm.nih.gov/15187106
Autor:
Tomoyuki Yamaguchi, Jun Shimizu, Tomohisa Nishioka, Kyoko Nakamura, Keiji Hirota, Tsutomu Chiba, Takashi Nomura, Shimon Sakaguchi, Kuibeom Ko, Sayuri Yamazaki
Publikováno v:
The Journal of Experimental Medicine
T cell stimulation via glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR) can evoke effective tumor immunity. A single administration of agonistic anti-GITR monoclonal antibody (mAb) to tumor-bearing mice intravenousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755949cfcdd321fd732a8557b3795993
https://doi.org/10.1084/jem.200509402092c
https://doi.org/10.1084/jem.200509402092c