Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Tomohisa Mori"'
Autor:
Yukari Suda, Keiko Nakamura, Fukiko Matsuyama, Yusuke Hamada, Hitoshi Makabe, Michiko Narita, Yasuyuki Nagumo, Tomohisa Mori, Naoko Kuzumaki, Minoru Narita
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-16 (2024)
Abstract While the excessive inflammation in cancer cachexia is well-known to be induced by the overproduction of inflammatory mediators in the periphery, microflora disruption and brain dysfunction are also considered to contribute to the induction
Externí odkaz:
https://doaj.org/article/b24fced65a274b84a4b588aadee5cdf6
Autor:
Sara Yoshida, Yusuke Hamada, Michiko Narita, Daisuke Sato, Kenichi Tanaka, Tomohisa Mori, Hiroyuki Tezuka, Yukari Suda, Hideki Tamura, Kazunori Aoki, Naoko Kuzumaki, Minoru Narita
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-11 (2023)
Abstract A growing body of evidence suggests that excess stress could aggravate tumor progression. The paraventricular nucleus (PVN) of the hypothalamus plays an important role in the adaptation to stress because the hypothalamic–pituitary–adrena
Externí odkaz:
https://doaj.org/article/e100ab25eb724f7290fcadacc48cd72f
Autor:
Kenichi Tanaka, Naoko Kuzumaki, Yusuke Hamada, Yukari Suda, Tomohisa Mori, Yasuyuki Nagumo, Minoru Narita
Publikováno v:
Neurobiology of Pain, Vol 14, Iss , Pp 100133- (2023)
Persistent pain signals cause brain dysfunction and can further prolong pain. In addition, the physical restriction of movement (e.g., by a cast) can cause stress and prolong pain. Recently, it has been recognized that exercise therapy including reha
Externí odkaz:
https://doaj.org/article/8188c153c21d4b67b58f0b1155a67954
Autor:
Yoshinori Takemura, Yuka Sudo, Tomoya Saeki, Shinji Kurata, Tsutomu Suzuki, Tomohisa Mori, Yasuhito Uezono
Publikováno v:
Journal of Pharmacological Sciences, Vol 149, Iss 3, Pp 85-92 (2022)
Neuropathic pain is refractory to opioid analgesics. Since there are functional linkages between μ-opioid receptors (MOR) and cannabinoid receptors (CBR), the present study was designed to investigate the interactions between MOR and CB1R based on a
Externí odkaz:
https://doaj.org/article/3cd30220daee4df6b6670578cbccf9fd
Autor:
Daisuke Sato, Yusuke Hamada, Michiko Narita, Tomohisa Mori, Hiroyuki Tezuka, Yukari Suda, Kenichi Tanaka, Sara Yoshida, Hideki Tamura, Akihiro Yamanaka, Emiko Senba, Naoko Kuzumaki, Minoru Narita
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-13 (2022)
Abstract Recent research has suggested that the mesolimbic dopamine network that mainly terminates in the nucleus accumbens may positively control the peripheral immune system. The activation of dopamine receptors in neurons in the nucleus accumbens
Externí odkaz:
https://doaj.org/article/0a1388f452bf4dafba3827ad0184455c
Autor:
Daisuke Sato, Michiko Narita, Yusuke Hamada, Tomohisa Mori, Kenichi Tanaka, Hideki Tamura, Akihiro Yamanaka, Ryosuke Matsui, Dai Watanabe, Yukari Suda, Emiko Senba, Moe Watanabe, Edita Navratilova, Frank Porreca, Naoko Kuzumaki, Minoru Narita
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-13 (2022)
Abstract Emerging evidence suggests that the mesolimbic dopaminergic network plays a role in the modulation of pain. As chronic pain conditions are associated with hypodopaminergic tone in the nucleus accumbens (NAc), we evaluated the effects of incr
Externí odkaz:
https://doaj.org/article/19e7e40f2ad442088b88dd6d70e75c50
Autor:
Yosuke Katsuda, Kenichi Tanaka, Tomohisa Mori, Michiko Narita, Hideyuki Takeshima, Takashige Kondo, Yoshiyuki Yamabe, Misa Matsufuji, Daisuke Sato, Yusuke Hamada, Keisuke Yamaguchi, Toshikazu Ushijima, Eiichi Inada, Naoko Kuzumaki, Masako Iseki, Minoru Narita
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract Chronic postsurgical pain (CPSP) is a serious problem. We developed a mouse model of CPSP induced by electrocautery and examined the mechanism of CPSP. In this mouse model, while both incision and electrocautery each produced acute allodynia
Externí odkaz:
https://doaj.org/article/7536ff5ff04648d28dd42d537aa3e442
Autor:
Tomoe Kanbara, Atsushi Nakamura, Keiko Takasu, Koichi Ogawa, Masahiro Shibasaki, Tomohisa Mori, Tsutomu Suzuki, Minoru Hasegawa, Gaku Sakaguchi, Toshiyuki Kanemasa
Publikováno v:
Journal of Pharmacological Sciences, Vol 126, Iss 3, Pp 264-273 (2014)
Abstract.: Oxaliplatin is a chemotherapeutic agent that induces chronic refractory neuropathy. To determine whether opioids effectively relieve this chronic neuropathy, we investigated the efficacies of morphine, oxycodone, and fentanyl, and the mech
Externí odkaz:
https://doaj.org/article/b372741afd934b13a488b7b5d4c7b3d6
Autor:
Tomohisa Mori, Tomoe Kanbara, Masato Harumiya, Yoshiyuki Iwase, Aki Masumoto, Sachiko Komiya, Atsushi Nakamura, Masahiro Shibasaki, Toshiyuki Kanemasa, Gaku Sakaguchi, Tsutomu Suzuki
Publikováno v:
Journal of Pharmacological Sciences, Vol 126, Iss 1, Pp 47-55 (2014)
The rewarding effects of μ-receptor agonists can be suppressed under several pain conditions. We recently showed that clinically used μ-receptor agonists possess efficacies for relieving the neuropathic pain induced by chemotherapeutic drug in rats
Externí odkaz:
https://doaj.org/article/65800cd82022411ba408d76dc260b2a8
Publikováno v:
Journal of Pharmacological Sciences, Vol 125, Iss 2, Pp 233-236 (2014)
Abstract.: Genetic factors affect locomotor activity, which mainly depends on the activation of dopaminergic systems. C57BL/6J-bgJbgJ (beige-J) mice, which exhibit deficiencies in immunological function, show behavioral hyperactivity. The present stu
Externí odkaz:
https://doaj.org/article/10ed6d013fce45d1b4f9fd227cd43d2c