Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tomohisa Hosokawa"'
Autor:
Tomohisa Hosokawa, Pin-Wu Liu
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Synaptic plasticity is a cellular mechanism of learning and memory. The synaptic strength can be persistently upregulated or downregulated to update the information sent to the neuronal network and form a memory engram. For its molecular mechanism, t
Externí odkaz:
https://doaj.org/article/bb7bca0166e24b6e934a650e5923430e
Publikováno v:
Current Opinion in Neurobiology. 69:84-92
Advances in microscopy techniques have revealed the details of synaptic nanodomains as defined by the segregation of specific molecules on or beneath both presynaptic and postsynaptic membranes. However, it is yet to be clarified how such segregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67cf7b5a0875a3b30ea419fc5d44d7ec
https://doi.org/10.1016/j.conb.2021.02.004
https://doi.org/10.1016/j.conb.2021.02.004
Autor:
Margaret M. Stratton, Erik I. Hallin, Rory O’Connell, Clive R. Bramham, Gopinath Muruganandam, Shreeram Akerkar, James J. Chambers, Yasunori Hayashi, Ian Merski, Petri Kursula, Helene J. Bustad, Remy Loris, Tambudzai Kanhema, Tomohisa Hosokawa, José M. Valpuesta, Marte I. Flydal, Christine Touma, Maria S. Eriksen, Daniela Lascu, Oleksii Nikolaienko, Sverre Grødem, Jorge Cuéllar, Aurora Martinez
Activity-regulated cytoskeleton-associated protein (Arc) is a protein interaction hub with diverse roles in intracellular neuronal signaling, and important functions in neuronal synaptic plasticity, memory, and postnatal cortical development. Arc has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62aa94e02e6b1e7bc97caa5f7b99e0e
http://urn.fi/urn:nbn:fi-fe2021070140815
http://urn.fi/urn:nbn:fi-fe2021070140815
Autor:
Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S. Ferreira, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang, Yasunori Hayashi
Transient information input to brain leads to persistent changes in synaptic circuit, thereby forming memory engrams. Synapse undergoes coordinated functional and structural changes during this process but how such changes are achieved by its compone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e1a0eafc45d5939fcdb551fd59a41f3
https://doi.org/10.1101/2020.11.25.397091
https://doi.org/10.1101/2020.11.25.397091
Autor:
Tomohisa, Hosokawa, Pin-Wu, Liu, Qixu, Cai, Joana S, Ferreira, Florian, Levet, Corey, Butler, Jean-Baptiste, Sibarita, Daniel, Choquet, Laurent, Groc, Eric, Hosy, Mingjie, Zhang, Yasunori, Hayashi
Publikováno v:
Nature neuroscience. 24(6)
Transient information input to the brain leads to persistent changes in synaptic circuits, contributing to the formation of memory engrams. Pre- and postsynaptic structures undergo coordinated functional and structural changes during this process, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62bddfbf8c5c8da8f44085b5b8371e69
https://pubmed.ncbi.nlm.nih.gov/34075223
https://pubmed.ncbi.nlm.nih.gov/34075223
Autor:
Maria S. Eriksen, Oleksii Nikolaienko, Sergei Baryshnikov, Clive R. Bramham, Yasunori Hayashi, Tomohisa Hosokawa, Erik I. Hallin, Petri Kursula, Sverre Grødem
Publikováno v:
Journal of Neurochemistry. 147:323-343
The activity-regulated cytoskeleton-associated protein (ARC) is critical for long-term synaptic plasticity and memory formation. Acting as a protein interaction hub, ARC regulates diverse signalling events in postsynaptic neurons. A protein interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7d57f8640f9691334f0754befa4ad0
https://doi.org/10.1111/jnc.14556
https://doi.org/10.1111/jnc.14556
Autor:
Clive R. Bramham, Gopinath Muruganandam, Remy Loris, Ian Merski, Marte I. Flydal, Jorge Cuéllar, James J. Chambers, Erik I. Hallin, Yasunori Hayashi, Margaret M. Stratton, Aurora Martinez, Tambudzai Kanhema, José M. Valpuesta, Sverre Grødem, Petri Kursula, Daniela Lascu, Helene J. Bustad, Shreeram Akerkar, Tomohisa Hosokawa, Maria S. Eriksen, Oleksii Nikolaienko, Rory O’Connell
Expression of activity-regulated cytoskeleton-associated protein (Arc) is critical for long-term synaptic plasticity, memory formation, and cognitive flexibility. The ability of Arc to self-associate and form virus-like capsid structures implies func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e0c52b566c41cdea77754975a20e89
Publikováno v:
Journal of Neurochemistry. 139:959-972
Since the discovery of long-term potentiation (LTP) about a half-century ago, Ca2+ /CaM-dependent protein kinase II (CaMKII) has been one of the most extensively studied components of the molecular machinery that regulate plasticity. This unique dode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e1a442a81c041a83be4e95d14c79ac
https://doi.org/10.1111/jnc.13672
https://doi.org/10.1111/jnc.13672
Publikováno v:
Structure. 28:290-300.e4
Shank1/2/3, major scaffold proteins in excitatory synapses, are frequently mutated in patients with psychiatric disorders. Although the Shank N-terminal domain and ankyrin repeats domain tandem (NTD-ANK) is known to bind to Ras and Rap1, the molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c9810a6257945340666f029cc28932
https://doi.org/10.1016/j.str.2019.11.018
https://doi.org/10.1016/j.str.2019.11.018
Autor:
Tomohisa Hosokawa
Publikováno v:
Electrophoresis Letters. 59:76-78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acc13609b04c8f06f9ab27cfc2fea40d
https://doi.org/10.2198/electroph.59.76
https://doi.org/10.2198/electroph.59.76