Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Tomohiro Yorimitsu"'
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40765 (2012)
Although it is well established that the coat protein complex II (COPII) mediates the transport of proteins and lipids from the endoplasmic reticulum (ER) to the Golgi apparatus, the regulation of the vesicular transport event and the mechanisms that
Externí odkaz:
https://doaj.org/article/d9db15bb229f48609caf5794703d1176
Autor:
Tomohiro Yorimitsu, Ken Sato
Publikováno v:
Journal of Cell Science. 136
COPII proteins assemble at ER exit sites (ERES) to form transport carriers. The initiation of COPII assembly in the yeast Saccharomyces cerevisiae is triggered by the ER membrane protein Sec12. Sec16, which plays a critical role in COPII organization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abde9f219b7900964ddcc9c4833b0275
https://doi.org/10.1242/jcs.261094
https://doi.org/10.1242/jcs.261094
Autor:
Ken Sato, Tomohiro Yorimitsu
Publikováno v:
Molecular Biology of the Cell. 31:149-156
COPII components undergo phosphorylation to drive ER export and autophagy. Here we found that the nonphosphorylatable Sec16 mutant exhibits no defect in ER export and autophagy. Our findings indicate that in Saccharomyces cerevisiae, Sec16 phosphoryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ae39440acf1d84695e4d0f8516a4869
https://doi.org/10.1091/mbc.e19-08-0477
https://doi.org/10.1091/mbc.e19-08-0477
Publikováno v:
Cell Structure and Function. 44:105-112
The coat protein complex II (COPII) generates transport carriers that deliver newly synthesized proteins from the endoplasmic reticulum (ER) to the Golgi apparatus. The small GTPase Sar1 is a well-known regulator of the assembly of the COPII coat. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae88ed63b9b8288ae93a7be9fdd81209
https://doi.org/10.1247/csf.19019
https://doi.org/10.1247/csf.19019
Autor:
Tomohiro, Yorimitsu, Ken, Sato
Publikováno v:
Molecular Biology of the Cell
Coat protein complex II (COPII) protein assembles at the endoplasmic reticulum exit site (ERES) to form vesicle carrier for transport from the ER to the Golgi apparatus. Sec16 has a critical role in COPII assembly to form ERES. Sec16∆565N mutant, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9b9a39ac9c9f1f3ba4767caea96e730
https://pubmed.ncbi.nlm.nih.gov/31851588
https://pubmed.ncbi.nlm.nih.gov/31851588
Autor:
Norito Sasaki, Ken Sato, Miharu Maeda, Kota Saito, Tomohiro Yorimitsu, Toshiaki Katada, Masano Shiraiwa
Secretory proteins synthesized within the endoplasmic reticulum (ER) are exported via coat protein complex II (COPII)-coated vesicles. The formation of the COPII-coated vesicles is initiated by activation of the small GTPase, Sar1. cTAGE5 directly in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d90793463b6f67617690b0e649b0cf
Autor:
Aisa Sakaguchi, Miyuki Sato, Katsuya Sato, Keiko Gengyo-Ando, Tomohiro Yorimitsu, Junichi Nakai, Taichi Hara, Ken Sato
Publikováno v:
Developmental Cell. 35(2):211-221
SummaryThe small GTPase Rab11 dynamically changes its location to regulate various cellular processes such as endocytic recycling, secretion, and cytokinesis. However, our knowledge of its upstream regulators is still limited. Here, we identify the R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d0d8fc3b7f696ea9938bdbcc57956b
Publikováno v:
FEBS Letters. 589:1234-1239
COPII vesicles are formed at specific subdomains of the ER, termed ER exit sites (ERESs). Depending on the cell type, ERESs number from a few to several hundred per cell. However, whether these ERESs are functionally and compositionally identical at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064f8ae083a73d90a0979f5b24393bb9
https://doi.org/10.1016/j.febslet.2015.04.006
https://doi.org/10.1016/j.febslet.2015.04.006
Publikováno v:
Journal of Cell Science.
COPII coat and the small GTPase Sar1 mediate protein export from the endoplasmic reticulum (ER) via specialized domains known as the ER exit sites. The peripheral ER protein Sec16 has been proposed to organize ER exit sites. However, it remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f687b79f58c894f1e6c255721ff55b
https://doi.org/10.1242/jcs.203844
https://doi.org/10.1242/jcs.203844
Publikováno v:
Molecular Biology of the Cell. 18:4180-4189
Autophagy is a highly conserved, degradative process in eukaryotic cells. The rapamycin-sensitive Tor kinase complex 1 (TORC1) has a major role in regulating induction of autophagy; however, the regulatory mechanisms are not fully understood. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27482a73a6c70ba849e32e3d99404d7d
https://doi.org/10.1091/mbc.e07-05-0485
https://doi.org/10.1091/mbc.e07-05-0485