Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tomohiro Kagi"'
Autor:
Takuya Noguchi, Yuto Sekiguchi, Yuki Kudoh, Rio Naganuma, Tomohiro Kagi, Akiko Nishidate, Kazuhiro Maeda, Chizuru Ishii, Takashi Toyama, Yusuke Hirata, Gi-Wook Hwang, Atsushi Matsuzawa
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Anticancer drug gefitinib causes inflammation-based side effects, such as interstitial pneumonitis. However, its mechanisms remain unknown. Here, we provide evidence that gefitinib elicits pro-inflammatory responses by promoting mature-inter
Externí odkaz:
https://doaj.org/article/8caaaf62bd0b45138093e5fa58c4ec7a
Autor:
Yuto Sekiguchi, Saya Takano, Takuya Noguchi, Tomohiro Kagi, Ryuto Komatsu, Maoko Tan, Yusuke Hirata, Atsushi Matsuzawa
Publikováno v:
The Journal of Immunology. 210:795-806
Gefitinib (GF), the tyrosine kinase inhibitor (TKI) targeting epidermal growth factor receptor, initiates lung inflammation through the NLR family pyrin domain containing 3 (NLRP3) inflammasome. However, the molecular targets and mechanisms underlyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2a81f0f3d9459686a41dfa0f8e23da0
https://doi.org/10.4049/jimmunol.2200611
https://doi.org/10.4049/jimmunol.2200611
Autor:
Tomohiro Kagi, Takuya Noguchi, Gi-Wook Hwang, Rio Naganuma, Atsushi Matsuzawa, Aya Inoue, Shuhei Hamano, Yuto Sekiguchi, Yusuke Hirata
Publikováno v:
The Journal of Antibiotics. 75:29-39
Polymyxin B (PMB) is an essential antibiotic active against multidrug-resistant bacteria, such as multidrug-resistant Pseudomonas aeruginosa (MDRP). However, the clinical use of PMB is limited, because PMB causes serious side effects, such as nephrot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eae5298f2efe26f0979117daa1475c3
https://doi.org/10.1038/s41429-021-00490-7
https://doi.org/10.1038/s41429-021-00490-7
Autor:
Tatsuya Shimada, Tomohiro Kagi, Miki Takahashi, Mei Tsuchida, Atsushi Matsuzawa, Hiromu Komatsu, Yusuke Hirata, Midori Suzuki, Takuya Noguchi, Yuki Kudoh
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5796, p 5796 (2021)
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5796, p 5796 (2021)
Volume 22
Issue 11
Receptor-interacting protein kinase 1 (RIPK1) is a key component of the tumor necrosis factor (TNF) receptor signaling complex that regulates both pro- and anti-apoptotic signaling. The reciprocal functions of RIPK1 in TNF signaling are determined by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776aa3d2caa9dc18dc0490f4f644b2d3
http://europepmc.org/articles/PMC8199362
http://europepmc.org/articles/PMC8199362
Publikováno v:
Oncotarget
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e3484e99868d3611675c0bfdb81323
https://pubmed.ncbi.nlm.nih.gov/34194630
https://pubmed.ncbi.nlm.nih.gov/34194630
Autor:
Mayuka Yamada, Yusuke Hirata, Takuya Noguchi, Tomohiro Kagi, Yukino Asai, Atsushi Matsuzawa, Midori Suzuki
Publikováno v:
International Journal of Molecular Sciences; Volume 21; Issue 24; Pages: 9497
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 9497, p 9497 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 9497, p 9497 (2020)
It is known that a wide variety of antibacterial agents stimulate generation of reactive oxygen species (ROS) in mammalian cells. However, its mechanisms are largely unknown. In this study, we unexpectedly found that transforming growth factor-β (TG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f98ac2af43500c2e2b2a1d216037aae