Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Tomohiko AKAHOSHI"'
Publikováno v:
Journal of Intensive Care, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Background Sympathetic nerve activity (SNA) plays a central role in the pathogenesis of several diseases such as sepsis and chronic kidney disease (CKD). Activation of microglia in the paraventricular nucleus of the hypothalamus (PVN) has be
Externí odkaz:
https://doaj.org/article/5f5c7186f62b41d1a390faddacf31ce7
Autor:
Kenta Momii, Hiroki Yagi, Tomoyuki Nezu, Kanji Ohsaki, Chen Man, Takahiro Tajimi, Takeshi Iyonaga, Masaaki Nishihara, Yuji Shono, Jun Maki, Tomohiko Akahoshi, Yasuharu Nakashima
Publikováno v:
Journal of Physical Fitness and Sports Medicine, Vol 13, Iss 4, Pp 131-137 (2024)
Pelvic fractures, accounting for 2–8% of skeletal injuries, present a significant burden in patients with trauma. High-energy incidents often result in severe pelvic trauma accompanied by comorbidities leading to high mortality rates. Managing thes
Externí odkaz:
https://doaj.org/article/6dd57d731c134cc39597a3f30bdf5b31
Autor:
Tomohiko Akahoshi MD, PhD, Noriyuki Kaku MD, PhD, Yuji Shono MD, PhD, Yuzo Yamamoto MD, PhD, Keita Takahashi MD, PhD, Takeshi Iyonaga MD, PhD, Kenta Momii MD, Masaaki Nishihara MD, PhD, Jun Maki MD, PhD, Kentaro Tokuda MD, PhD, Ken Yamaura MD, PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
Recombinant antithrombin gamma (rAT) is reported as an effective drug for patients with disseminated intravascular coagulation (DIC) in Japan. As the appropriate dose and targeted AT activity remain unknown, this study aimed to determine these aspect
Externí odkaz:
https://doaj.org/article/6ceaab12e00a4186a01dbda1ab35f50d
Autor:
Yuji Shono, Satomi Mezuki, Tomohiko Akahoshi, Masaaki Nishihara, Noriyuki Kaku, Jun Maki, Kentaro Tokuda, Takanari Kitazono
Publikováno v:
Journal of International Medical Research, Vol 50 (2022)
Objective This study was performed to evaluate the correlation between parameters measured by bedside ultrasonography and detection of intracranial organic lesions in patients with impaired consciousness in an intensive care unit (ICU) setting. Metho
Externí odkaz:
https://doaj.org/article/66fdd7232564401fad7903cda181e453
Autor:
Toshifumi Fujiwara, Kentaro Tokuda, Kenta Momii, Kyohei Shiomoto, Hidetoshi Tsushima, Yukio Akasaki, Satoshi Ikemura, Jun-ichi Fukushi, Jun Maki, Noriyuki Kaku, Tomohiko Akahoshi, Tomoaki Taguchi, Yasuharu Nakashima
Publikováno v:
BMC Rheumatology, Vol 4, Iss 1, Pp 1-11 (2020)
Abstract Background Patients with rheumatoid arthritis (RA) have high mortality risk and are frequently treated in intensive care units (ICUs). Methods This was a retrospective observational study. This study included 67 patients (20 males, 47 female
Externí odkaz:
https://doaj.org/article/1971ec62be2b43368ba0f7e5ea360fff
Autor:
Yukie Mizuta, Tomohiko Akahoshi, Jie Guo, Shuo Zhang, Sayoko Narahara, Takahito Kawano, Masaharu Murata, Kentaro Tokuda, Masatoshi Eto, Makoto Hashizume, Ken Yamaura
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Background Mesenchymal stem cells (MSCs), including adipose-derived mesenchymal stem cells (ADSCs), have been shown to attenuate organ damage in acute respiratory distress syndrome (ARDS) and sepsis; however, the underlying mechanisms are no
Externí odkaz:
https://doaj.org/article/4a660f607e6b48d2b198cd4e7f39c3e8
Autor:
Md. Zahangir Hosain, Fuminori Hyodo, Takeshi Mori, Koyo Takahashi, Yusuke Nagao, Hinako Eto, Masaharu Murata, Tomohiko Akahoshi, Masayuki Matsuo, Yoshiki Katayama
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract Redox status influences the course of the inflammatory, metabolic, and proliferative liver diseases. Oxidative stress is thought to play a crucial and sustained role in the pathological progression of early steatosis to severe hepatitis, fib
Externí odkaz:
https://doaj.org/article/d7b4042cffb2419d898ba3cab0fe5402
Autor:
Takashi Nagata, Tomohiko Akahoshi, Michiko Sugino, Wataru Ishii, Ryoji Iizuka, Takafumi Shinjo, Yoshimitsu Izawa, Michiaki Hata, Alan Kawarai Lefor
Publikováno v:
Surgical Case Reports, Vol 5, Iss 1, Pp 1-5 (2019)
Abstract Background The management of cardiac trauma requires rapid intervention in the emergency room, facilitated by a surgeon with prior experience to have good outcomes. Many surgeons have little experience in the requisite procedures. We report
Externí odkaz:
https://doaj.org/article/eeb3388a6ad942498382a80a430985ba
Publikováno v:
Acute Medicine & Surgery, Vol 6, Iss 4, Pp 400-403 (2019)
Background Open abdomen management (OAM) is used not only for trauma but also for treatment of peritonitis. However, the rate of successful fascial closure in patients with OAM remains low. Case Presentation The patient was a 38‐year‐old morbidly
Externí odkaz:
https://doaj.org/article/bedd53fb675140e49a87601ea6c45935
Autor:
Yukie Mizuta, Tomohiko Akahoshi, Hinako Eto, Fuminori Hyodo, Masaharu Murata, Kentaro Tokuda, Masatoshi Eto, Ken Yamaura
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1454 (2022)
Doxorubicin (DOX) induces dose-dependent cardiotoxicity via oxidative stress and abnormal mitochondrial function in the myocardium. Therefore, a noninvasive in vivo imaging procedure for monitoring the redox status of the heart may aid in monitoring
Externí odkaz:
https://doaj.org/article/f3e0e4735a604ab887660f6246267ebb