Výsledky vyhledávání - "Tomohiko, Hayashi"

Akademický článek

Physical pictures of rotation mechanisms of F1- and V1-ATPases: Leading roles of translational, configurational entropy of water

Autor: Satoshi Yasuda, Tomohiko Hayashi, Takeshi Murata, Masahiro Kinoshita

Publikováno v: Frontiers in Molecular Biosciences, Vol 10 (2023)

We aim to develop a theory based on a concept other than the chemo-mechanical coupling (transduction of chemical free energy of ATP to mechanical work) for an ATP-driven protein complex. Experimental results conflicting with the chemo-mechanical coup

Externí odkaz: https://doaj.org/article/6837efa10a184b5cbe2faac86f7ffcc6

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Akademický článek

Percutaneous Transluminal Septal Myocardial Ablation for Hypertrophic Obstructive Cardiomyopathy Under Extracorporeal Membrane Oxygenation Support

Autor: Takahiro Kobayashi, MD, Hiroyuki Takaoka, MD, PhD, Haruka Sasaki, MD, Manami Takahashi, MD, Kan Saito, MD, Tomohiko Hayashi, MD, PhD, Kwangho Lee, MD, PhD, Yoshihide Fujimoto, MD, PhD, Masato Yamanouchi, MD, PhD, Yoshio Kobayashi, MD, PhD

Publikováno v: JACC: Case Reports, Vol 2, Iss 12, Pp 1917-1922 (2020)

We report the case of a 70-year-old woman with hypertrophic obstructive cardiomyopathy, who was admitted because of severe heart failure and cardiogenic shock and mechanical support requiring extracorporeal membrane oxygenation. She recovered well by

Externí odkaz: https://doaj.org/article/2237bc4226734ab09a4abe602232bb1d

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Akademický článek

Successful cryoablation of ventricular extrasystoles originating from the vicinity of the left anterior fascicle

Autor: Takatsugu Kajiyama, Yusuke Kondo, Masahiro Nakano, Kazuo Miyazawa, Miyo Nakano, Tomohiko Hayashi, Ryo Ito, Haruhiro Takahira, Yoshio Kobayashi

Publikováno v: Journal of Arrhythmia, Vol 36, Iss 3, Pp 518-521 (2020)

Abstract A 32‐year‐old male received catheter ablation of frequent ventricular extrasystoles (VEs). His electrocardiogram showed monomorphic VEs with an inferior axis and early precordial transitional zone. During electrophysiological testing, a

Externí odkaz: https://doaj.org/article/c4f649f570c14f46967e934e7829a1dc

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Akademický článek

Combination of a leadless pacemaker and subcutaneous implantable cardioverter defibrillator therapy for a Japanese patient with prosthetic valve endocarditis

Autor: Ryo Ito, Yusuke Kondo, Joachim Winter, Tomohiko Hayashi, Miyo Nakano, Takatsugu Kajiyama, Masahiro Nakano, Yoshio Kobayashi

Publikováno v: Journal of Arrhythmia, Vol 35, Iss 2, Pp 311-313 (2019)

Abstract The subcutaneous implantable cardioverter defibrillator (S‐ICD) system was developed for defibrillation therapy that does not affect the heart and vasculature. S‐ICD is preferred over transvenous ICD for patients with a history of recurr

Externí odkaz: https://doaj.org/article/1c4ff1fda8a8478688bb2f7d5c89671d

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Development of an Outward Proton Pumping Rhodopsin with a New Record in Thermostability by Means of Amino Acid Mutations

Autor: Satoshi Yasuda, Tomoki Akiyama, Keiichi Kojima, Tetsuya Ueta, Tomohiko Hayashi, Satoshi Ogasawara, Satoru Nagatoishi, Kouhei Tsumoto, Naoki Kunishima, Yuki Sudo, Masahiro Kinoshita, Takeshi Murata

Publikováno v: The Journal of Physical Chemistry B. 126:1004-1015

We have developed a methodology for identifying further thermostabilizing mutations for an intrinsically thermostable membrane protein. The methodology comprises the following steps: (1) identifying thermostabilizing single mutations (TSSMs) for resi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2febf0a29aae85da604553bf728405a
https://doi.org/10.1021/acs.jpcb.1c08684

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A methodology for creating mutants of G‐protein coupled receptors stabilized in active state by combining statistical thermodynamics and evolutionary molecular engineering

Autor: Taisei Yamamoto, Satoshi Yasuda, Rinshi S. Kasai, Ryosuke Nakano, Simon Hikiri, Kanna Sugaya, Tomohiko Hayashi, Satoshi Ogasawara, Mitsunori Shiroishi, Takahiro K. Fujiwara, Masahiro Kinoshita, Takeshi Murata

Publikováno v: Protein Science. 31

We challenged the stabilization of a G-protein coupled receptor (GPCR) in the active state solely by multiple amino-acid mutations without the agonist binding. For many GPCRs, the free energy of the active state is higher than that of the inactive st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396168dd3f65bdf173a92cb29e0c8114
https://doi.org/10.1002/pro.4425

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