Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tomoharu Kanie"'
Autor:
Ivan T. Lee, Tsuguhisa Nakayama, Chien-Ting Wu, Yury Goltsev, Sizun Jiang, Phillip A. Gall, Chun-Kang Liao, Liang-Chun Shih, Christian M. Schürch, David R. McIlwain, Pauline Chu, Nicole A. Borchard, David Zarabanda, Sachi S. Dholakia, Angela Yang, Dayoung Kim, Han Chen, Tomoharu Kanie, Chia-Der Lin, Ming-Hsui Tsai, Katie M. Phillips, Raymond Kim, Jonathan B. Overdevest, Matthew A. Tyler, Carol H. Yan, Chih-Feng Lin, Yi-Tsen Lin, Da-Tian Bau, Gregory J. Tsay, Zara M. Patel, Yung-An Tsou, Alexandar Tzankov, Matthias S. Matter, Chih-Jaan Tai, Te-Huei Yeh, Peter H. Hwang, Garry P. Nolan, Jayakar V. Nayak, Peter K. Jackson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Understanding how SARS-CoV-2 gains initial entry into the human body is a key step towards the development of prophylaxes and therapeutics for COVID-19. Here, the authors show that ACE2, the receptor for SARS-CoV-2, is abundantly expressed in the mot
Externí odkaz:
https://doaj.org/article/46b19154257e4119b14a2d65b124b2f3
Autor:
Tomoharu Kanie, Peter Jackson
Publikováno v:
Bio-Protocol, Vol 8, Iss 7 (2018)
GTPases are molecular switches that cycle between the inactive GDP-bound state and the active GTP-bound state. GTPases exchange nucleotides either by its intrinsic nucleotide exchange or by interaction with guanine nucleotide exchange factors (GEFs).
Externí odkaz:
https://doaj.org/article/cff5b4db8b4a4499b7ffa249791d0fa0
Autor:
Jiang Min, Shenglan Yang, Yang Cai, David R. Vanderwall, Zhiping Wu, Shuping Li, Songlan Liu, Beibei Liu, Jie Wang, Yingjun Ding, Junxiong Chen, Chao Jiang, Jonathan D. Wren, Anna Csiszar, Zoltan Ungvari, Céline Greco, Tomoharu Kanie, Junmin Peng, Xin A. Zhang
Publikováno v:
Cellular and Molecular Life Sciences. 80
SummaryThe primary cilium is a microtubule-based organelle that cycles through assembly and disassembly. In many cell types, formation of the cilium is initiated by recruitment of ciliary vesicles to the distal appendage of the mother centriole. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d482f4ef3865fb7dffaf0905638e5b
https://doi.org/10.1101/2023.01.06.523037
https://doi.org/10.1101/2023.01.06.523037
SummaryDistal appendages are nine-fold symmetric blade-like structures attached to the distal end of the mother centriole. These structures are critical for formation of the primary cilium, by regulating at least four critical steps: ciliary vesicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4410bc77fc162768395d745d0f5b197b
https://doi.org/10.1101/2023.01.06.522944
https://doi.org/10.1101/2023.01.06.522944
Autor:
Angela Yang, Da Tian Bau, Yung An Tsou, Jayakar V. Nayak, Han Chen, David Zarabanda, Phillip A. Gall, Matthias S. Matter, Chih Feng Lin, Nicole A. Borchard, Yi Tsen Lin, Yury Goltsev, Garry P. Nolan, Sachi S. Dholakia, Katie M. Phillips, Tsuguhisa Nakayama, Chia-Der Lin, Jonathan B. Overdevest, Te-Huei Yeh, Matthew A. Tyler, Chien-Ting Wu, Alexandar Tzankov, Liang Chun Shih, Pauline Chu, Raymond Kim, Sizun Jiang, David R. McIlwain, Ivan T. Lee, Tomoharu Kanie, Christian M. Schürch, Peter K. Jackson, Zara M. Patel, Chun Kang Liao, Ming Hsui Tsai, Carol H. Yan, Dayoung Kim, Peter H. Hwang, Chih Jaan Tai, Gregory J. Tsay
Publikováno v:
Nature communications, vol 11, iss 1
medRxiv
article-version (status) pre
article-version (number) 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
medRxiv
article-version (status) pre
article-version (number) 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The coronavirus SARS-CoV-2 is the causative agent of the ongoing severe acute respiratory disease pandemic COVID-19. Tissue and cellular tropism is one key to understanding the pathogenesis of SARS-CoV-2. We investigate the expression and subcellular
Autor:
Chien-Ting Wu, David Zarabanda, David R. McIlwain, Angela Yang, Yury Goltsev, Te-Huei Yeh, Ivan T. Lee, Tsuguhisa Nakayama, Carol H. Yan, Chih Jaan Tai, Raymond Kim, Gregory J. Tsay, Chun-Kang Liao, Chia-Der Lin, Jayakar V. Nayak, Katie M. Phillips, Matthew A. Tyler, Garry P. Nolan, Ming Hsui Tsai, Sizun Jiang, Sachi S. Dholakia, Dayoung Kim, Tomoharu Kanie, Chih-Feng Lin, Christian M. Schürch, Liang-Chun Shih, Phillip A. Gall, Da Tian Bau, Yung An Tsou, Pauline Chu, Yi-Tsen Lin, Nicole A. Borchard, Jonathan B. Overdevest, Peter K. Jackson, Peter H. Hwang, Zara M. Patel
We investigated the expression and subcellular localization of the SARS-CoV-2 receptor, angiotensin-converting enzyme 2 (ACE2), within the upper (nasal) and lower (pulmonary) respiratory tracts of healthy human donors. We detected ACE2 protein expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e791bcca99b6758c88f2aff0e57706
https://doi.org/10.1101/2020.05.08.20092866
https://doi.org/10.1101/2020.05.08.20092866
Autor:
Peter K. Jackson, Tomoharu Kanie
GTPases are molecular switches that cycle between the inactive GDP-bound state and the active GTP-bound state. GTPases exchange nucleotides either by its intrinsic nucleotide exchange or by interaction with guanine nucleotide exchange factors (GEFs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8448827daf9cdc19eee21e43f4a01902
https://europepmc.org/articles/PMC6017992/
https://europepmc.org/articles/PMC6017992/
Autor:
Keiko Nakayama, Yuki Tateishi, Akinobu Matsumoto, Eiji Hara, Tomoharu Kanie, Keiichi I. Nakayama
Publikováno v:
Biochemical and Biophysical Research Communications. 427:285-292
Timely exit of cells from the cell cycle is essential for proper cell differentiation during embryogenesis. Cyclin-dependent kinase (CDK) inhibitors (CKIs) of the Cip/Kip family (p21, p27, and p57) are negative regulators of cell cycle progression an