Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Tomofusa Tsuchiya"'
Autor:
Nami Yasuda, Tomoko Fujita, Takahiro Fujioka, Mei Tagawa, Naoki Kohira, Kensho Torimaru, Sumiko Shiota, Takanori Kumagai, Daichi Morita, Wakano Ogawa, Tomofusa Tsuchiya, Teruo Kuroda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Multidrug-resistant Pseudomonas aeruginosa (MDRP) is one of the most important pathogens in clinical practice. To clarify the mechanisms contributing to its emergence, we isolated MDRPs using the P. aeruginosa PAO1, the whole genome sequence
Externí odkaz:
https://doaj.org/article/8c6cc076f38940e080b687e7b1942031
Autor:
Shinsuke Toba, Yusuke Minato, Yuma Kondo, Kanami Hoshikawa, Shu Minagawa, Shiho Komaki, Takanori Kumagai, Yasuyuki Matoba, Daichi Morita, Wakano Ogawa, Naomasa Gotoh, Tomofusa Tsuchiya, Teruo Kuroda
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract We investigated the role of the resistance-nodulation-cell division superfamily (RND) efflux system on intrinsic multidrug resistance in Serratia marcescens. We identified eight putative RND efflux system genes in the S. marcescens Db10 geno
Externí odkaz:
https://doaj.org/article/4eae5c160dad49e0ba77c692766c9fd9
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121619 (2015)
We previously described the cloning of genes related to drug resistance from Klebsiella pneumoniae MGH78578. Of these, we identified a putative gene encoding a MATE-type multidrug efflux pump, and named it ketM. Escherichia coli KAM32 possessing ketM
Externí odkaz:
https://doaj.org/article/fc8db24e5140463499b59d49a12fa5e4
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59525 (2013)
Multidrug efflux pumps play an important role as a self-defense system in bacteria. Bacterial multidrug efflux pumps are classified into five families based on structure and coupling energy: resistance-nodulation-cell division (RND), small multidrug
Externí odkaz:
https://doaj.org/article/a3605b908b404f43826b6125f4561b76
Autor:
Tomofusa Tsuchiya, Wakano Ogawa, Motoyasu Onishi, Takanori Kishino, Ryoko Kitagawa, Rui Ting Ni, Futoshi Matsubara, Teruo Kuroda, Minako Mizusawa
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
The emergence of multidrug-resistant Klebsiella pneumoniae is a worldwide problem. K. pneumoniae possesses numerous resistant genes in its genome. We isolated mutants resistant to various antimicrobials in vitro and investigated the importance of int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c732b6d496dab78259f6615af34c1f
http://link.springer.com/article/10.1038/s41598-020-67820-x
http://link.springer.com/article/10.1038/s41598-020-67820-x
Autor:
Yasuyuki Matoba, Tomofusa Tsuchiya, Yusuke Minato, Wakano Ogawa, Shu Minagawa, Takanori Kumagai, Kanami Hoshikawa, Shinsuke Toba, Naomasa Gotoh, Shiho Komaki, Daichi Morita, Teruo Kuroda, Yuma Kondo
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
We investigated the role of the resistance-nodulation-cell division superfamily (RND) efflux system on intrinsic multidrug resistance in Serratia marcescens. We identified eight putative RND efflux system genes in the S. marcescens Db10 genome that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717be8d329a01d426f78b21a5d94895b
https://doi.org/10.1038/s41598-019-41237-7
https://doi.org/10.1038/s41598-019-41237-7
Autor:
Wakano Ogawa, Eri Nishiyama, Teruo Kuroda, Shinya Okamura, Tsutomu Hatano, Tomohiro Yamazaki, Nao Otsuka, Tomofusa Tsuchiya, Shoko Taniguchi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1850:1245-1252
Background Multidrug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococci (VRE), cause serious infections at clinical sites, for which the development of new drugs is necessary. We screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fff59959a8dba61da7fb762e8812c83
https://doi.org/10.1016/j.bbagen.2015.02.012
https://doi.org/10.1016/j.bbagen.2015.02.012
Autor:
Hirotaka Matsuo, Yoichi Yamada, Norihiro Ohtaguro, Naomoto Suzuki, Nobutaka Imamura, Tomofusa Tsuchiya, Yasuaki Yoshida, Motoshi Hirai
Publikováno v:
Biological & Pharmaceutical Bulletin. 38:889-892
Biofilm is one virulence factor of bacteria. It contributes not only to bacterial adherence to many kinds of infection-establishing surfaces, but also to bacterial resistance against antimicrobial agents and antiseptic agents. Thus, inhibitors of bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1b6bf58dd2352ec692635548793b138
https://doi.org/10.1248/bpb.b15-00053
https://doi.org/10.1248/bpb.b15-00053
Publikováno v:
Journal of natural products. 80(10)
Three new ellagitannin oligomers, isorugosins H (1), I (2), and J (3), together with 11 known hydrolyzable tannins were isolated from an aqueous acetone extract of the fresh leaves of Liquidambar formosana. Their chemical structures were elucidated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23e8f6c55192135f768c9df1f30d252
https://pubmed.ncbi.nlm.nih.gov/29019685
https://pubmed.ncbi.nlm.nih.gov/29019685
Autor:
Tomofusa Tsuchiya, Taira Matsuo, Teruo Kuroda, Hirotaka Hiyoshi, Koji Nakamura, Wakano Ogawa, Toshio Kodama, Taro Mikami
Publikováno v:
MicrobiologyOpen
Resistance nodulation cell division (RND)-type efflux transporters play the main role in intrinsic resistance to various antimicrobial agents in many gram-negative bacteria. Here, we estimated 12 RND-type efflux transporter genes in Vibrio parahaemol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cae668189066ade184f98cdfd52cfcf
https://doi.org/10.1002/mbo3.100
https://doi.org/10.1002/mbo3.100