Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Tomofumi Uchida"'
2
TMC-52A to D, Novel Cysteine Proteinase Inhibitors, Produced by Gliocladium sp
Autor: Saburo Komatsubara, Kengo Isshiki, Toru Okuda, Maki Nishio, Tomofumi Uchida, Naoki Sakurai
Publikováno v: The Journal of Antibiotics. 51:629-634
New cysteine proteinase inhibitors, TMC-52A, B, C, and D, were isolated from the fungal fermentation broth. On the basis of a taxonomical study, the producing strain, F-2665, was characterized as Gliocladium sp. Spectroscopic analyses and chemical de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97cd80b4a1b52bd2c31ac8b648efb4d0
https://doi.org/10.7164/antibiotics.51.629
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3
TMC-1 A, B, C and D, New Antibiotics of the Manumycin Group Produced by Streptomyces sp. Taxonomy, Production, Isolation, Physico-chemical Properties, Structure Elucidation and Biological Properties
Autor: Kimio Kawano, Maki Nishio, Saburo Komatsubara, Noriyuki Nakanishi, Jun Kohno, Tomofumi Uchida, Shin-Ichi Suzuki
Publikováno v: The Journal of Antibiotics. 49:1212-1220
Four new antitumor antibiotics, TMC-1 A, B, C and D were isolated from a fermentation broth of Streptomyces sp. A-230. Spectroscopic studies have shown that TMC-1 A to D were new members of the manumycin class of antibiotics. These antibiotics showed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e5d2053422da744029e6e3f1a70567
https://doi.org/10.7164/antibiotics.49.1212
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4
ChemInform Abstract: TMC-1 A, B, C, and D, New Antibiotics of the Manumycin Group Produced by Streptomyces sp. Taxonomy, Production, Isolation, Physico-Chemical Properties, Structure Elucidation, and Biological Properties
Autor: Shin-Ichi Suzuki, Maki Nishio, Noriyuki Nakanishi, Tomofumi Uchida, Jun Kohno, Kimio Kawano, Saburo Komatsubara
Publikováno v: ChemInform. 28
Four new antitumor antibiotics, TMC-1 A, B, C and D were isolated from a fermentation broth of Streptomyces sp. A-230. Spectroscopic studies have shown that TMC-1 A to D were new members of the manumycin class of antibiotics. These antibiotics showed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7af288ff5f074ed846883d82596f56bf
https://doi.org/10.1002/chin.199725226
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5
ChemInform Abstract: TMC-52A to D, Novel Cysteine Proteinase Inhibitors, Produced by Gliocladium sp
Autor: Kengo Isshiki, Maki Nishio, Saburo Komatsubara, Tomofumi Uchida, Toru Okuda, Naoki Sakurai
Publikováno v: ChemInform. 29
New cysteine proteinase inhibitors, TMC-52A, B, C, and D, were isolated from the fungal fermentation broth. On the basis of a taxonomical study, the producing strain, F-2665, was characterized as Gliocladium sp. Spectroscopic analyses and chemical de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::efc69334b3f451d117969bb8dc121a40
https://doi.org/10.1002/chin.199850225
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6
Aurantiamide acetate, a selective cathepsin inhibitor, produced by Aspergillus penicilloides
Autor: Sumiko Tanaka, Yasuyuki Asai, Toru Okuda, Naoki Sakurai, Tomofumi Uchida, Saburo Komatsubara, Kengo Isshiki, Maki Nishio
Publikováno v: Bioscience, biotechnology, and biochemistry. 65(5)
Aurantiamide acetate was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate inhibited cysteine proteinases, in particular, cathepsin L (3.4.22.15) and B (3.4.22.1) with IC50 of 12 microM and 49
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ad308192642f07e8dfeadfa3645dba
https://pubmed.ncbi.nlm.nih.gov/11440138
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7
4-acylaminophenol derivatives as novel lipoxygenase inhibitors: synthesis and inhibitory effect on 5-lipoxygenase and leukotriene B4 production
Autor: Hirozumi Inoue, Matsuo Kikuchi, Yoshimasa Hashimura, Masaaki Nagasawa, Tomofumi Uchida, Tomoyasu Taniguchi, Kei Tsuzurahara
Publikováno v: Biologicalpharmaceutical bulletin. 17(8)
Structure-activity relationships in the inhibitory effects of 4-acylaminophenol derivatives on the 5-lipoxygenase (5-LOX) from RBL-1 cells and leukotriene B4 (LTB4) production by guinea pig neutrophils were studied. When the N-acyl group was n-octano
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be79aad4710117717e14d8a90bc64da
https://pubmed.ncbi.nlm.nih.gov/7820104
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8
A metaphosphate-dependent nicotinamide adenine dinucleotide kinase from Brevibacterium ammoniagenes
Autor: Kousaku Murata, Jyoji Kato, Tomofumi Uchida, Ichiro Chibata
Publikováno v: Agricultural and Biological Chemistry. 44:1165-1172
The enzyme utilizing metaphosphate for nicotinamide adenine dinucleotide phosphorylation was purified 500-fold from B. ammoniagenes and its properties were studied. The isolated enzyme appeared homogeneous on disc gel electrophoresis; its molecular w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac48481a445634479994e8cbcb4567ce
https://doi.org/10.1271/bbb1961.44.1165
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10
Polyphosphate kinase: Distribution, some properties and its application as an ATP regeneration system
Autor: Ichiro Chibata, Kousaku Murata, Jyoji Kato, Tomofumi Uchida
Publikováno v: Agricultural and Biological Chemistry. 52:1471-1477
The distribution and some properties of polyphosphate kinase, that catalyzes the formation of polyphosphate from ATP, were investigated. High enzyme activity was found in Alcaligenes faecalis, Brevibacterium ammoniagenes, Escherichia coli, Micrococus
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e52f76e14cd3e94e4d5082d03efaad
https://doi.org/10.1271/bbb1961.52.1471
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