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Relationship between gut microbiota-derived substances and vascular function: focus on indoxyl sulfate and trimethylamine-N-oxide

Autor: Takayuki Matsumoto, Natsume Taguchi, Madoka Yoshioka, Tomoe Osada, Kumiko Taguchi, Tsuneo Kobayashi

Publikováno v: Folia Pharmacologica Japonica. 157:316-320

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cccb6a8601bb70a55da44a28333f3635
https://doi.org/10.1254/fpj.22029

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[Relationship between gut microbiota-derived substances and vascular function: focus on indoxyl sulfate and trimethylamine-N-oxide]

Autor: Takayuki, Matsumoto, Natsume, Taguchi, Madoka, Yoshioka, Tomoe, Osada, Kumiko, Taguchi, Tsuneo, Kobayashi

Publikováno v: Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 157(5)

Emerging evidences suggest that gut microbiota-derived substances play a pivotal role in the regulation of host homeostasis including vascular function. Actually, these substances and/or their metabolites can be presented in circulation and local tis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2dc3cb4d35cab517d669dc7ef1df7346
https://pubmed.ncbi.nlm.nih.gov/36047143

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Methylglyoxal impairs ATP- and UTP-induced relaxation in the rat carotid arteries

Autor: Takayuki Matsumoto, Miyo Kudo, Tomoe Osada, Kumiko Taguchi, Tsuneo Kobayashi

Publikováno v: European Journal of Pharmacology. 933:175259

Although methylglyoxal (MGO), a highly reactive dicarbonyl compound, influences the functioning of the vasculature, modulating its effects on vascular reactivity to various substances remains unclear, especially purinoceptor ligands. Therefore, we so

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6b3bab7a4b1faacbdc55c7989c89b0
https://doi.org/10.1016/j.ejphar.2022.175259

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Methylglyoxal-induced enhancement of uridine diphosphate-mediated contraction in rat femoral artery was due to activation of p38 MAPK and Syk tyrosine kinase

Autor: Takayuki Matsumoto, Madoka Yoshioka, Akane Nogami, Miyo Kudo, Tomoe Osada, Haruka Ogasawara, Natsume Taguchi, Sayaka Endo, Keigo Nakamura, Aiko Yamada, Kumiko Taguchi, Tsuneo Kobayashi

Publikováno v: Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:3-B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8efce9e7e48fc23d11e9b50ba8c03e08
https://doi.org/10.1254/jpssuppl.96.0_3-b-o08-4

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