Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Tomoaki Sobajima"'
Autor:
Tatsuya Hagino, Takafumi Kato, Go Kasuya, Kan Kobayashi, Tsukasa Kusakizako, Shin Hamamoto, Tomoaki Sobajima, Yuichiro Fujiwara, Keitaro Yamashita, Hisashi Kawasaki, Andrés D. Maturana, Tomohiro Nishizawa, Osamu Nureki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
VCCN1 is a plant homolog of bestrophin channels and tunes photoreaction as a voltage-gated anion channel at thylakoids. Here, authors report the cryo-EM structures and functional features of apple VCCN1, with insights into its activation mechanism.
Externí odkaz:
https://doaj.org/article/8eb76456739540798060b72b508dd7d4
Autor:
Andreas Gerondopoulos, Philipp Bräuer, Tomoaki Sobajima, Zhiyi Wu, Joanne L Parker, Philip C Biggin, Francis A Barr, Simon Newstead
Publikováno v:
eLife, Vol 10 (2021)
ER proteins of widely differing abundance are retrieved from the Golgi by the KDEL-receptor. Abundant ER proteins tend to have KDEL rather than HDEL signals, whereas ADEL and DDEL are not used in most organisms. Here, we explore the mechanism of sele
Externí odkaz:
https://doaj.org/article/f2972a9d44914cddb9615d861a93414a
Autor:
Tomoaki Sobajima, Shin-ichiro Yoshimura, Tomohiko Iwano, Masataka Kunii, Masahiko Watanabe, Nur Atik, Sotaro Mushiake, Eiichi Morii, Yoshihisa Koyama, Eiji Miyoshi, Akihiro Harada
Publikováno v:
Biology Open, Vol 4, Iss 1, Pp 86-94 (2014)
The small GTPase Rab11 plays an important role in the recycling of proteins to the plasma membrane as well as in polarised transport in epithelial cells and neurons. We generated conditional knockout mice deficient in Rab11a. Rab11a-deficient mice ar
Externí odkaz:
https://doaj.org/article/94b9242d6fd3498883c7f34bd477c111
Delays in mitosis trigger a p53-dependent arrest in G1 of the following cell cycle, enabling cells to react to changes promoting aneuploidy [1-10]. How delays in mitosis are sensed and result in cells becoming arrested in the subsequent G1 phase is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e219588e75300d1b821cfdd4c0fc876f
https://doi.org/10.1101/2023.05.26.542398
https://doi.org/10.1101/2023.05.26.542398
Autor:
Tomoaki Sobajima, Katarzyna M. Kowalczyk, Stefanos Skylakakis, Daniel Hayward, Luke J. Fulcher, Colette Neary, Caleb Batley, Samvid Kurlekar, Emile Roberts, Ulrike Gruneberg, Francis A. Barr
Publikováno v:
Journal of Cell Biology. 222
Amplification of the mitotic kinase Aurora A or loss of its regulator protein phosphatase 6 (PP6) have emerged as drivers of genome instability. Cells lacking PPP6C, the catalytic subunit of PP6, have amplified Aurora A activity, and as we show here,
Autor:
Tomoaki Sobajima, Katarzyna M. Kowalczyk, Stefanos Skylakakis, Daniel Hayward, Luke J. Fulcher, Colette Neary, Caleb Batley, Samvid Kurlekar, Emile Roberts, Ulrike Gruneberg, Francis A. Barr
Amplification of the mitotic kinase Aurora A or loss of its regulator protein phosphatase 6 (PP6) have emerged as drivers of genome instability. Cells lacking PPP6C, the catalytic subunit of PP6, have amplified Aurora A activity and as we show here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6200583c144ec5cb53c2459779e3647
https://doi.org/10.1101/2022.05.23.492953
https://doi.org/10.1101/2022.05.23.492953
Publikováno v:
Journal of Biological Chemistry. 299:102985
Autor:
Philipp Bräuer, Francis A. Barr, Joanne L. Parker, Tomoaki Sobajima, Simon Newstead, Zhiyi Wu, Andreas Gerondopoulos, Philip C. Biggin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::518f09ad25f4e67e8605bc574643cd26
https://doi.org/10.7554/elife.68380.sa2
https://doi.org/10.7554/elife.68380.sa2
Autor:
Tatsuya Hagino, Takafumi Kato, Go Kasuya, Kan Kobayashi, Tsukasa Kusakizako, Shin Hamamoto, Tomoaki Sobajima, Yuichiro Fujiwara, Keitaro Yamashita, Hisashi Kawasaki, Andrés D. Maturana, Tomohiro Nishizawa, Osamu Nureki
Publikováno v:
Nature communications. 13(1)
In the light reaction of plant photosynthesis, modulation of electron transport chain reactions is important to maintain the efficiency of photosynthesis under a broad range of light intensities. VCCN1 was recently identified as a voltage-gated chlor
Autor:
Tomoaki Sobajima, Andreas Gerondopoulos, Joanne L. Parker, Francis A. Barr, Zhemeng Wu, Philipp Bräuer, Simon Newstead, Philip C. Biggin
The KDEL-retrieval pathway captures escaped ER proteins with a KDEL or variant C-terminal signal at acidic pH in the Golgi and releases them at neutral pH in the ER. To address the mechanism of signal binding and the molecular basis for differences i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::554b3b1b4012a0797a86a8d5cbfaea64
https://doi.org/10.1101/2021.03.21.436307
https://doi.org/10.1101/2021.03.21.436307