Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tomoaki Kamiyoshihara"'
Autor:
Hidenobu Kondo, Kenji Fujisawa, Yukikazu Hayashi, Takuhiro Yamaguchi, Toshiaki Nojima, Hideki Suganami, Tomoaki Kamiyoshihara, Hisataka Fujiwara, Ryohei Tanigawa
Publikováno v:
Therapeutic Innovation & Regulatory Science
Background Risk-based monitoring (RBM) is a slow uptake in some trial sponsors. There are three main reasons for this. First, there is the fear of making large investments into advanced RBM technology solutions. Second, it is considered that RBM is m
Autor:
Kenji Uéda, Tomoaki Kamiyoshihara, Hiroshi Kihara, Mitsuru Tashiro, Sakurako Shimotakahara, Kouki Kasai, Masaki Kojima
Publikováno v:
Biochemical and biophysical research communications. 369(3)
alpha-Synuclein is the major component of the filamentous Lewy bodies and Lewy-related neurites, neuropathological hallmarks of Parkinson's disease. Although numerous studies on alpha-synuclein fibrillation have been reported, the molecular mechanism
Publikováno v:
Biochemical and biophysical research communications. 355(2)
One of the most well known characteristics for Parkinson's disease (PD) is a polymerization of wild-type or mutant alpha-synuclein into aggregates and fibrils, commonly observed as Lewy bodies and Lewy neuritis in PD patients. Although numerous studi