Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Tomoaki Kahyo"'
Autor:
Yusuke Takanashi, Tomoaki Kahyo, Keigo Sekihara, Akikazu Kawase, Mitsutoshi Setou, Kazuhito Funai
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Cancer prognosis remains a critical clinical challenge. Lipidomic analysis via mass spectrometry (MS) offers the potential for objective prognostic prediction, leveraging the distinct lipid profiles of cancer patient-derived specimens. This
Externí odkaz:
https://doaj.org/article/62905d9b2d324a2e82aeffd03737fc0f
Autor:
Md Foyzur Rahman, Ariful Islam, Md. Monirul Islam, Md. Al Mamun, Lili Xu, Takumi Sakamoto, Tomohito Sato, Yutaka Takahashi, Tomoaki Kahyo, Satoka Aoyagi, Kozo Kaibuchi, Mitsutoshi Setou
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7969 (2024)
Mass spectrometry imaging (MSI) is essential for visualizing drug distribution, metabolites, and significant biomolecules in pharmacokinetic studies. This study mainly focuses on imipramine, a tricyclic antidepressant that affects endogenous metaboli
Externí odkaz:
https://doaj.org/article/f4c1e4d10e6f4edea990350cb8eb9acc
Autor:
Jing Yan, Tomoaki Kahyo, Hengsen Zhang, Yashuang Ping, Chi Zhang, Shuyun Jiang, Qianqing Ji, Rafia Ferdous, Md. Shoriful Islam, Soho Oyama, Shuhei Aramaki, Tomohito Sato, Mst. Afsana Mimi, Md. Mahmudul Hasan, Mitsutoshi Setou
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7353 (2024)
Aberrant aggregation of misfolded alpha-synuclein (α-syn), a major pathological hallmark of related neurodegenerative diseases such as Parkinson’s disease (PD), can translocate between cells. Ubiquitin-like 3 (UBL3) is a membrane-anchored ubiquiti
Externí odkaz:
https://doaj.org/article/d84e67a081cd4ced8c818efb59d42165
Autor:
Takashi Yamashita, Yusuke Takanashi, Asuka Uebayashi, Mikako Oka, Kiyomichi Mizuno, Akikazu Kawase, Soho Oyama, Takuya Kitamoto, Minako Kondo, Shiho Omori, Hong Tao, Yutaka Takahashi, Takumi Sakamoto, Tomoaki Kahyo, Haruhiko Sugimura, Mitsutoshi Setou, Norihiko Shiiya, Kazuhito Funai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract In patients with unresectable non-small cell lung cancer, histological diagnosis is frequently based on small biopsy specimens unsuitable for histological diagnosis when they are severely crushed and do not retain their morphology. Therefore
Externí odkaz:
https://doaj.org/article/e00a28344bf0464d98235353aafd471d
Autor:
Ryuta Muraki, Yoshifumi Morita, Shinya Ida, Ryo Kitajima, Satoru Furuhashi, Makoto Takeda, Hirotoshi Kikuchi, Yoshihiro Hiramatsu, Yusuke Takanashi, Yasushi Hamaya, Ken Sugimoto, Jun Ito, Kazuhito Kawata, Hideya Kawasaki, Tomohito Sato, Tomoaki Kahyo, Mitsutoshi Setou, Hiroya Takeuchi
Publikováno v:
Cancer Medicine, Vol 12, Iss 12, Pp 13007-13018 (2023)
Abstract Background Owing to the lack of definite diagnostic modalities, it is challenging to distinguish malignant cases of cholangiocarcinoma (CCA), which often causes biliary tract obstruction, from benign ones. Here, we investigated a novel lipid
Externí odkaz:
https://doaj.org/article/b93b3e59f1924026a113e27563dd7db0
Autor:
Md. Monirul Islam, Md Foyzur Rahman, Ariful Islam, Mst. Sayela Afroz, Md. Al Mamun, Md. Muedur Rahman, Md Maniruzzaman, Lili Xu, Takumi Sakamoto, Yutaka Takahashi, Tomohito Sato, Tomoaki Kahyo, Mitsutoshi Setou
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4840 (2024)
Knowledge of gender-specific drug distributions in different organs are of great importance for personalized medicine and reducing toxicity. However, such drug distributions have not been well studied. In this study, we investigated potential differe
Externí odkaz:
https://doaj.org/article/eba4480da56a462eaf855d4048fee3ab
Autor:
Yusuke Takanashi, Tomoaki Kahyo, Takamitsu Hayakawa, Keigo Sekihara, Akikazu Kawase, Minako Kondo, Takuya Kitamoto, Yutaka Takahashi, Tomohito Sato, Haruhiko Sugimura, Norihiko Shiiya, Mitsutoshi Setou, Kazuhito Funai
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Background The risk of postoperative recurrence is higher in lung cancer patients who smoke than non-smokers. However, objective evaluation of the postoperative recurrence risk is difficult using conventional pathological prognostic factors
Externí odkaz:
https://doaj.org/article/63916a4cf17b4a1289035f440ce18f37
Autor:
Md. Al Mamun, Md. Mahamodun Nabi, Tomohito Sato, Shuhei Aramaki, Yusuke Takanashi, Takumi Sakamoto, Kaito Hizume, Chikako Mori, Maiha Yasue, Masataka Ozaki, Ariful Islam, Tomoaki Kahyo, Makoto Horikawa, Yutaka Takahashi, Shigetoshi Okazaki, Kentaro Ohishi, Yu Nagashima, Keiji Seno, Yoshihiro Hotta, Mitsutoshi Setou
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Photoisomerization of lipids has been well studied. As for the eyes, photoisomerization from 11-cis isomer to all-trans-retinal is well-known as the first step of the visual transduction in the photoreceptors. In addition to that, there woul
Externí odkaz:
https://doaj.org/article/35da13d8e6504e47bfbe2b723513c5b7
Autor:
Fumito Sano, Kenji Kikushima, Seico Benner, Lili Xu, Tomoaki Kahyo, Hidenori Yamasue, Mitsutoshi Setou
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundThough various mechanisms have been proposed for the pathophysiology of schizophrenia, the full extent of these mechanisms remains unclear, and little is known about the relationships among them. We carried out trans-omics analyses by compa
Externí odkaz:
https://doaj.org/article/ac1a8b0b4e204e3aac813143b03e0203
Autor:
Keitaro Akita, Kenji Kikushima, Takenori Ikoma, Ariful Islam, Tomohito Sato, Taisei Yamamoto, Tomoaki Kahyo, Mitsutoshi Setou, Yuichiro Maekawa
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-7 (2022)
Abstract Objective Hypertrophic cardiomyopathy (HCM) is a common genetic disease with diverse morphology, symptoms, and prognosis. Hypertrophied myocardium metabolism has not been explored in detail. We assessed the association between myocardium lip
Externí odkaz:
https://doaj.org/article/1b7c00df4c4749dabcc5c057dfc7829e