Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tomo Suga"'
Autor:
Ryoko Araki, Tomo Suga, Yuko Hoki, Kaori Imadome, Misato Sunayama, Satoshi Kamimura, Mayumi Fujita, Masumi Abe
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Genomic aberrations are a critical impediment for the safe medical use of iPSCs and their origin and developmental mechanisms remain unknown. Here we find through WGS analysis of human and mouse iPSC lines that genomic mutations are de novo
Externí odkaz:
https://doaj.org/article/c9a67a6a7e1842b9b98236430276c28b
Autor:
Ryoko Araki, Yuko Hoki, Tomo Suga, Chizuka Obara, Misato Sunayama, Kaori Imadome, Mayumi Fujita, Satoshi Kamimura, Miki Nakamura, Sayaka Wakayama, Andras Nagy, Teruhiko Wakayama, Masumi Abe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Point mutations have been found in induced pluripotent stem cells (iPSCs) but when they arise is unclear. Here, the authors show that a G1/S cell cycle checkpoint deficiency transiently occurs early in genome reprogramming, suggesting a common develo
Externí odkaz:
https://doaj.org/article/fead58306cee46a28867f75c35cbe41b
Autor:
Takashi Imai, Mayumi Iwakawa, Kenichi Ishikawa, Atsuko Ishikawa, Izumi Matsumoto, Yoshimi Ohtsuka, Tomo Suga, Yuichi Michikawa
Publikováno v:
Sensors, Vol 8, Iss 4, Pp 2722-2735 (2008)
A visible sensor array system for simultaneous multiple SNP genotyping has been developed using a new plastic base with specific surface chemistry. Discrimination of SNP alleles is carried out by an allele-specific extension reaction using immobilize
Externí odkaz:
https://doaj.org/article/bbfcf161afc744628010ced3c8290536
Autor:
Kaori Imadome, Yuko Hoki, Satoshi Kamimura, Mayumi Fujita, Ryoko Araki, Misato Sunayama, Miki Nakamura, Masumi Abe, Tomo Suga
Publikováno v:
Stem Cell Reports
Summary We here demonstrate that microsatellite (MS) alterations are elevated in both mouse and human induced pluripotent stem cells (iPSCs), but importantly we have now identified a type of human iPSC in which these alterations are considerably redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56afb0f853941c51ddb22c4646d98e43
http://europepmc.org/articles/PMC8514972
http://europepmc.org/articles/PMC8514972
Autor:
Kamimura, Satoshi, Suga, Tomo, Hoki, Yuko, Sunayama, Misato, Imadome, Kaori, Fujita, Mayumi, Nakamura, Miki, Araki, Ryoko, Abe, Masumi, Satoshi, Kamimura, Tomo, Suga, Yuko, Fujimori, Misato, Sunayama, Kaori, Imadome, Mayumi, Fujita, Miki, Nakamura, Ryoko, Araki, Masumi, Abe
Publikováno v:
Stem cell reports. 16(10):2503-2519
We here demonstrate that microsatellite (MS) alterations are elevated in both mouse and human induced pluripotent stem cells (iPSCs), but importantly we have now identified a type of human iPSC in which these alterations are considerably reduced. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::a4d15e81581bdf9461f058f8f30b6434
https://repo.qst.go.jp/records/84323
https://repo.qst.go.jp/records/84323
Autor:
Yuko Hoki, Misato Sunayama, Mayumi Fujita, Teruhiko Wakayama, Tomo Suga, Andras Nagy, Chizuka Obara, Masumi Abe, Kaori Imadome, Satoshi Kamimura, Miki Nakamura, Ryoko Araki, Sayaka Wakayama
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
A number of point mutations have been identified in reprogrammed pluripotent stem cells such as iPSCs and ntESCs. The molecular basis for these mutations has remained elusive however, which is a considerable impediment to their potential medical appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16243956b17388ffd7cc727446c2f0c
http://link.springer.com/article/10.1038/s41467-019-13830-x
http://link.springer.com/article/10.1038/s41467-019-13830-x
Autor:
Araki, Ryoko, Hoki, Yuko, Suga, Tomo, Obara, Chizuka, Sunayama, Misato, Imadome, Kaori, Fujita, Mayumi, Kamimura, Satoshi, Nakamura, Miki, Wakayama, Sayaka, Nagy, Andras, Wakayama, Teruhiko, Abe, Masumi, Ryoko, Araki, Yuko, Fujimori, Tomo, Suga, Chizuka, Obara, Misato, Sunayama, Kaori, Imadome, Mayumi, Fujita, Satoshi, Kamimura, Masumi, Abe
Publikováno v:
Nature communications. 11(1):197
A number of point mutations have been identified in reprogrammed pluripotent stem cells such as iPSCs and ntESCs. The molecular basis for these mutations has remained elusive however, which is a considerable impediment to their potential medical appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::e1e7a694b67ad82388a9c73a8b620cbc
https://repo.qst.go.jp/records/78509
https://repo.qst.go.jp/records/78509
Autor:
Tomo Suga, Shizuko Kakinuma, Shinobu Hirano-Sakairi, Yi Shang, Mayumi Nishimura, Yoshiko Amasaki, Yotaro Kodama, Kazuhiro Daino, Takashi Imai, Mitsuaki A. Yoshida, Akifumi Nakata, Yoshiya Shimada, Atsuko Ishikawa
Publikováno v:
Carcinogenesis. 40(2)
Biallelic germline mutations in the DNA mismatch repair gene MLH1 lead to constitutional mismatch repair-deficiency syndrome and an increased risk for childhood hematopoietic malignancies, including lymphoma and leukemia. To examine how Mlh1 dysfunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9e49282070d3e4d3362ea296f1f466
https://pubmed.ncbi.nlm.nih.gov/30721949
https://pubmed.ncbi.nlm.nih.gov/30721949
Autor:
Tomo Suga, Catharine M L West, Petra Seibold, Charlotte E. Coles, Marie-Luise Sautter-Bihl, Juergen Debus, C. Anne Koch, Christopher J. Talbot, Sabine Behrens, Gillian C. Barnett, John Yarnold, Frederik Wenz, Irmgard Helmbold, Judith M Bliss, Odilia Popanda, Alison M. Dunning, Neil G. Burnet, Barry S. Rosenstein, Katherine A. Vallis, Takashi Imai, R. Paul Symonds, Tim Rattay, Sarah L. Kerns, David Azria, Jenny Chang-Claude, Thomas Schnabel, Johannes Claßen, Céline Bourgier, Peter Schmezer
Publikováno v:
International Journal of Radiation Oncology-Biology-Physics
International Journal of Radiation Oncology-Biology-Physics, Elsevier, 2015, 92 (5), pp.1084-1092. ⟨10.1016/j.ijrobp.2015.04.011⟩
International Journal of Radiation Oncology-Biology-Physics, Elsevier, 2015, 92 (5), pp.1084-1092. ⟨10.1016/j.ijrobp.2015.04.011⟩
International audience; PURPOSE:To identify single-nucleotide polymorphisms (SNPs) in oxidative stress-related genes associated with risk of late toxicities in breast cancer patients receiving radiation therapy.METHODS AND MATERIALS:Using a 2-stage d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31db2d3afd5b5b6eeb54fb62616d32d9
https://doi.org/10.1016/j.ijrobp.2015.04.011
https://doi.org/10.1016/j.ijrobp.2015.04.011
Autor:
Shingo Kato, Tomo Suga, Daijiro Kobayashi, Masaru Wakatsuki, Takashi Nakano, Tatsuya Ohno, Noriyuki Okonogi, Tadashi Kamada, Takashi Imai
Human papillomavirus (HPV) infection is well known as a major etiological risk factor associated with carcinogenesis in uterine cervical cancer. However, few reports have investigated the association between HPV genotype and outcome in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e783d3151968584a196c72cb2af33ec
https://europepmc.org/articles/PMC5769372/
https://europepmc.org/articles/PMC5769372/
