Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tommy Weiss-Sadan"'
Autor:
Tommy Weiss-Sadan, David Maimoun, Diana Oelschlagel, Farnusch Kaschani, Danny Misiak, Hanmant Gaikwad, Yael Ben-Nun, Emannuelle Merquiol, Adi Anaki, Darya Tsvirkun, Markus Kaiser, Patrick Michl, Israel Gotsman, Galia Blum
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 3, Pp 550-572 (2019)
Externí odkaz:
https://doaj.org/article/cc7862781b9e48159bc7e84ff1a784b8
Autor:
Yonit Yitzhak, Hanmant Gaikwad, Tommy Weiss-Sadan, Emmanuelle Merquiol, Boris Turk, Galia Blum
Publikováno v:
Molecules, Vol 27, Iss 3, p 842 (2022)
Cysteine cathepsin proteases are found under normal conditions in the lysosomal compartments of cells, where they play pivotal roles in a variety of cellular processes such as protein and lipid metabolism, autophagy, antigen presentation, and cell gr
Externí odkaz:
https://doaj.org/article/438747093c6747078330898ca0c90b67
Autor:
Tommy Weiss-Sadan, Maolin Ge, Addriaan de Groot, Alexander Carlin, Magdy Gohar, Hannah Fischer, Lei Shi, Ting-Yu Wei, Charles H. Adelmann, Tristan Vornbäumen, Benedkit R. Dürr, Mariko Takahashi, Marianne Richter, Junbing Zhang, Tzu-Yi Yang, Vindhya Vijay, Makiko Hayashi, David E. Fischer, Aaron N. Hata, Thales Papaginanakopoulos, Raul Mostoslavsky, Nabeel Bardeesy, Liron Bar-Peled
Multiple cancers regulate oxidative stress by activating the transcription factor NRF2 through mutation of its negative regulator KEAP1. NRF2 has been studied extensively in KEAP1-mutant cancers, however the role of this pathway in cancers with wildt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6bca0f03c908f5891a12becbd18f540
https://doi.org/10.1101/2022.08.31.506025
https://doi.org/10.1101/2022.08.31.506025
Autor:
Junbing Zhang, Claire M. Simpson, Jacqueline Berner, Harrison B. Chong, Jiafeng Fang, Zehra Ordulu, Tommy Weiss-Sadan, Anthony P. Possemato, Stefan Harry, Mariko Takahashi, Tzu-yi Yang, Marianne Richter, Himani Patel, Abby E. Smith, Alexander D. Carlin, Adriaan F. Hubertus de Groot, Konstantin Wolf, Lei Shi, Ting-Yu Wei, Benedikt R. Dürr, Nicholas J. Chen, Tristan Vornbäumen, Nina O. Wichmann, Mohammed S. Mahamdeh, Venkatesh Pooladanda, Yusuke Matoba, Shaan Kumar, Eugene Kim, Sara Bouberhan, Esther Oliva, Bo R. Rueda, Roy J. Soberman, Nabeel Bardeesy, Brian B. Liau, Michael Lawrence, Matt P. Stokes, Sean A. Beausoleil, Liron Bar-Peled
Publikováno v:
Cell. 186:2361-2379.e25
Autor:
Tommy Weiss-Sadan, Maolin Ge, Makiko Hayashi, Magdy Gohar, Cong-Hui Yao, Adriaan de Groot, Stefan Harry, Alexander Carlin, Hannah Fischer, Lei Shi, Ting-Yu Wei, Charles H. Adelmann, Konstantin Wolf, Tristan Vornbäumen, Benedikt R. Dürr, Mariko Takahashi, Marianne Richter, Junbing Zhang, Tzu-Yi Yang, Vindhya Vijay, David E. Fisher, Aaron N. Hata, Marcia C. Haigis, Raul Mostoslavsky, Nabeel Bardeesy, Thales Papagiannakopoulos, Liron Bar-Peled
Publikováno v:
Cell Metab
Autor:
Emmanuelle Merquiol, Diana Oelschlagel, Darya Tsvirkun, David Maimoun, Hanmant Gaikwad, Farnusch Kaschani, Danny Misiak, Israel Gotsman, Patrick Michl, Yael Ben-Nun, Tommy Weiss-Sadan, Markus Kaiser, Galia Blum, Adi Anaki
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 3, Pp 550-572 (2019)
BACKGROUND/AIMS: Atherosclerosis underlies the majority of cardiovascular events, consequent to non-resolving inflammation. Considerable evidence implicates autophagy dysfunction at the core of this inflammatory condition, but the basis of this dysfu
Autor:
Tommy Weiss Sadan, Werner Schmitz, Galia Blum, Patrick Michl, Seth J. Salpeter, Sebastian Krug, Almut Schulze, Diana Oelschlaegel
Publikováno v:
Cancers
Volume 12
Issue 9
Cancers, Vol 12, Iss 2579, p 2579 (2020)
Volume 12
Issue 9
Cancers, Vol 12, Iss 2579, p 2579 (2020)
Stroma-infiltrating immune cells, such as tumor-associated macrophages (TAM), play an important role in regulating tumor progression and chemoresistance. These effects are mostly conveyed by secreted mediators, among them several cathepsin proteases.
Autor:
Yael Ben-Nun, Galia Blum, Tommy Weiss-Sadan, Emmanuelle Merquiol, Darya Tsvirkun, Karen Meir, Ilan Matok, Ivan Zlotver, Rachela Popovtzer
Publikováno v:
Journal of the American Chemical Society
X-ray CT instruments are among the most available, efficient, and cost-effective imaging modalities in hospitals. The field of CT molecular imaging is emerging which relies mainly on the detection of gold nanoparticles and iodine-containing compounds
Autor:
Tommy Weiss-Sadan, Mohamed Mahameed, Gal Itzhak, Emmanuelle Merquiol, Zhanru Yu, Farnusch Kaschani, Boaz Tirosh, Benedikt M. Kessler, Markus Kaiser, Yael Ben-Nun, Galia Blum, Adi Anaki
Publikováno v:
Molecular & Cellular Proteomics : MCP
Remodeling of cellular metabolism is a genuine feature of rapidly growing cells. Herein we report that mouse embryonic fibroblasts, lacking the Cathepsin L (Cts L) gene, proliferate faster than wild-types and display a noticeable glycolytic shift to
A Theranostic Cathepsin Activity-Based Probe for Noninvasive Intervention in Cardiovascular Diseases
Autor:
David Maimoun, Ihab Abd-Elrahman, Emmanuelle Merquiol, Yael Ben-Nun, Galia Blum, Israel Gotsman, Tommy Weiss-Sadan
Publikováno v:
Theranostics
Despite the common use of lipid-lowering medications, cardiovascular diseases continue to be a significant health concern. Atherosclerosis, one of the most frequent causes of cardiovascular morbidity, involves extensive inflammatory activity and remo