Zobrazeno 1 - 4
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pro vyhledávání: '"Tommy Hui"'
Publikováno v:
Hui, T, Sørensen, E S & Rittling, S R 2015, ' Osteopontin binding to the alpha 4 integrin requires highest affinity integrin conformation, but is independent of post-translational modifications of osteopontin ', Matrix Biology, vol. 41, pp. 19-25 . https://doi.org/10.1016/j.matbio.2014.11.005
Osteopontin (OPN) is a ligand for the α4ß1 integrin, but the physiological importance of this binding is not well understood. Here, we have assessed the effect of post-translational modifications on OPN binding to the α4 integrin on cultured human
Autor:
Aritsune Matsui, Christopher D Johnston, Tommy Hui, Montserrat Ruiz-Torruella, Susan R. Rittling, Ziyad Allahem, Rani Singh
Publikováno v:
Immunology. 150(1)
Osteopontin (OPN) is a pro-inflammatory protein that paradoxically protects against inflammation and bone destruction in a mouse model of endodontic infection. Here we have tested the hypothesis that this effect of OPN is mediated by effects on migra
Publikováno v:
British Journal of Cancer
Background: The integrin-binding protein osteopontin is strongly associated with tumour development, yet is an abundant dietary component as a constituent of human and bovine milk. Therefore, we tested the effect of orally administered osteopontin (o
Publikováno v:
The Journal of Immunology. 194:192.4-192.4
The integrin binding protein osteopontin (OPN) protects against bone destruction in a mouse model of endodontic infection. Here we have tested the hypothesis that this effect of OPN is mediated by effects on migration of innate immune cells to the si