Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tommy Noh"'
Autor:
Tommy Noh, Yankel Gabet, Jon Cogan, Yunfan Shi, Archana Tank, Tomoyo Sasaki, Braden Criswell, Alexis Dixon, Christopher Lee, Joseph Tam, Thomas Kohler, Eran Segev, Lisa Kockeritz, James Woodgett, Ralph Müller, Yang Chai, Elisheva Smith, Itai Bab, Baruch Frenkel
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5438 (2009)
We investigated the role of Lef1, one of the four transcription factors that transmit Wnt signaling to the genome, in the regulation of bone mass. Microcomputed tomographic analysis of 13- and 17-week-old mice revealed significantly reduced trabecula
Externí odkaz:
https://doaj.org/article/6eb67f210fce47ed908c41e79dd00a92
Publikováno v:
Growth Factors. 26:226-237
Pharmacological glucocorticoids (GCs) inhibit bone formation, leading to osteoporosis. GCs inhibit bone morphogenetic protein-2 (Bmp2) expression, and rhBMP-2 restores mineralization in GC-arrested osteoblast cultures. To better understand how GCs re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad02450c3945fcf4a061619f700a17e4
https://doi.org/10.1080/08977190802277880
https://doi.org/10.1080/08977190802277880
Autor:
Tommy Noh, Jon Cogan, Baruch Frenkel, Elisheva Smith, Dilan B. Samarawickrama, Nathalie Leclerc
Publikováno v:
Journal of Cellular Biochemistry. 103:1938-1951
Krox20 is expressed in osteoblasts and chondrocytes, and is required for trabecular bone formation during embryogenesis. Here we show by RT-qPCR and Western blot analysis that Krox20 is up-regulated during late stages of osteoblast differentiation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65093335cb31e0887297d5027254eb7
https://doi.org/10.1002/jcb.21587
https://doi.org/10.1002/jcb.21587
Publikováno v:
Journal of Biological Chemistry. 280:37495-37502
In osteoblasts, the mitogen-activated protein kinases ERK1/2 and p38 as well as the cAMP-response element-binding protein (CREB) have been implicated in the regulation of proliferation and differentiation. The osteogenic growth peptide (OGP) is a 14-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee55bc97636e1f3b99bf649ce7aa7be
https://doi.org/10.1074/jbc.m503861200
https://doi.org/10.1074/jbc.m503861200
Autor:
Baruch Frenkel, Nathalie Leclerc, Tommy Noh, Adele L. Boskey, Artem Barski, Cynthia A. Luppen, Elisheva Smith, Arvinder Khokhar
Publikováno v:
Journal of Biological Chemistry. 278:44995-45003
Glucocorticoids (GCs) inhibit bone formation in vivo. In MC3T3-E1 osteoblasts, chronic administration of 1 μm dexamethasone (DEX) starting at confluency results in >98% inhibition of bone morphogenetic protein 2 (BMP-2) expression and apatite minera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e278e994b31512cedd1112b0304cfcc
https://doi.org/10.1074/jbc.m306730200
https://doi.org/10.1074/jbc.m306730200
Publikováno v:
Journal of cellular physiology. 226(4)
Synthetic glucocorticoids (GCs) like dexamethasone (DEX) are effective immunosuppressants indicated for autoimmune and inflammatory diseases. However, they often promote osteoporosis and bone fractures. Here, we investigated the anti-mitogenic effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34815dccac52d2440d89736f7332cd51
https://pubmed.ncbi.nlm.nih.gov/20857405
https://pubmed.ncbi.nlm.nih.gov/20857405
Autor:
Tomoyo Sasaki, Yang Chai, Braden Criswell, Eran Segev, Archana Tank, Yunfan Shi, Baruch Frenkel, Ralph Müller, Joseph Tam, Christopher Lee, Yankel Gabet, Thomas Kohler, Itai Bab, Tommy Noh, Jon Cogan, Elisheva Smith, James R. Woodgett, Lisa Kockeritz, Alexis Dixon
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 5, p e5438 (2009)
PLoS ONE, 4 (5)
PLoS ONE, Vol 4, Iss 5, p e5438 (2009)
PLoS ONE, 4 (5)
We investigated the role of Lef1, one of the four transcription factors that transmit Wnt signaling to the genome, in the regulation of bone mass. Microcomputed tomographic analysis of 13- and 17-week-old mice revealed significantly reduced trabecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8080ea8dac912da5a3952dd61e2ec3
http://europepmc.org/articles/PMC2673053
http://europepmc.org/articles/PMC2673053
Publikováno v:
Arthritis and rheumatism. 52(3)
Objective Glucocorticoids are widely used for the management of rheumatoid arthritis. Osteoporosis is a major side effect of glucocorticoid therapy and is attributable to inhibition of bone formation. We developed an osteoblast culture system in whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c95dd7157bb587c9044ac5a22f168a
https://pubmed.ncbi.nlm.nih.gov/15751078
https://pubmed.ncbi.nlm.nih.gov/15751078
Autor:
M Namdar-Attar, Olga Lahat, Joseph G. Hacia, Ralph Müller, Todd E. Meyerrose, Itai Bab, Mazen W. Karaman, Thomas Kohler, Natti Bab, Jan A. Nolta, Baruch Frenkel, Tommy Noh, Jingjing Li, Elisheva Smith, Ting T. Chen
Publikováno v:
Nucleic Acids Research, 33 (4)
Nucleic Acids Research
Nucleic acids research, vol 33, iss 4
Nucleic Acids Research
Nucleic acids research, vol 33, iss 4
Nucleic Acids Research, 33 (4)
ISSN:1362-4962
ISSN:0301-5610
ISSN:1362-4962
ISSN:0301-5610
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f0437ee15187cd42ffd49d9bc5f5c4
https://hdl.handle.net/20.500.11850/33572
https://hdl.handle.net/20.500.11850/33572
Autor:
Tommy Noh, Joseph Tam, Braiden Criswell, Lisa Kockeritz, Elisheva Smith, Baruch Frenkel, Jon Cogan, James R. Woodgett, Thomas Kohler, Alexis Dixon, Archana Tank, Yankel Gabet, Itai Bab, Ralph Müller, Eran Regev, Tomoyo Sasaki, Yang Chai
Publikováno v:
Bone. 42:S50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3feead7a36ea250f2cdcfa0c87f62728
https://doi.org/10.1016/j.bone.2007.12.085
https://doi.org/10.1016/j.bone.2007.12.085