Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Tommi Paakkonen"'
Autor:
Anne-Mari Mustonen, Nina Lehmonen, Tommi Paakkonen, Marja Raekallio, Reijo Käkelä, Tytti Niemelä, Anna Mykkänen, Sanna P. Sihvo, Petteri Nieminen
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-11 (2023)
Abstract Background Individual fatty acids (FAs) and their derivatives (lipid mediators) with pro-inflammatory or dual anti-inflammatory and pro-resolving properties have potential to influence the health of joint tissues. Osteoarthritis (OA) is an a
Externí odkaz:
https://doaj.org/article/fd63cb62e4c44c7ba4043da51c797e70
Autor:
Anne-Mari Mustonen, Nina Lehmonen, Sanna Oikari, Janne Capra, Marja Raekallio, Anna Mykkänen, Tommi Paakkonen, Kirsi Rilla, Tytti Niemelä, Petteri Nieminen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Osteoarthritis (OA) is a degenerative joint disease with inadequately understood pathogenesis leading to pain and functional limitations. Extracellular vesicles (EVs) released by synovial joint cells can induce both pro- and anti-OA effects.
Externí odkaz:
https://doaj.org/article/a36d9259827c4c89bc26e97231e52563
Autor:
Anne-Mari Mustonen, Janne Capra, Kirsi Rilla, Petri Lehenkari, Sanna Oikari, Tommi Kääriäinen, Antti Joukainen, Heikki Kröger, Tommi Paakkonen, Johanna Matilainen, Petteri Nieminen
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Hyaluronic acid (HA) is the major extracellular matrix glycosaminoglycan with a reduced synovial fluid (SF) concentration in arthropathies. Cell-derived extracellular vesicles (EV) have also been proposed to contribute to pathogen
Externí odkaz:
https://doaj.org/article/89c9f8d37bee4a819b7b9812c189bc41
Autor:
Aapo Ristaniemi, Jari Torniainen, Tommi Paakkonen, Lauri Stenroth, Mikko A.J. Finnilä, Petri Tanska, Juha Töyräs, Rami K. Korhonen
Publikováno v:
Data in Brief, Vol 36, Iss , Pp 106976- (2021)
Knee joint ligaments and patellar tendon are rope-like tissues that enable the proper function of the knee by connecting the bones that form the joint. A better understanding of ligament structure-function relationships is needed to develop objective
Externí odkaz:
https://doaj.org/article/40fa3aa2cff64e74ae0c3b92f1e09695
Autor:
Anne-Mari Mustonen, Reijo Käkelä, Petri Lehenkari, Johanna Huhtakangas, Sanna Turunen, Antti Joukainen, Tommi Kääriäinen, Tommi Paakkonen, Heikki Kröger, Petteri Nieminen
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-11 (2019)
Abstract Background Infrapatellar fat pad (IFP) has recently emerged as a potential source of inflammation in knee arthropathies. It has been proposed to be one source of adipocytokines, fatty acids (FA), and FA-derived lipid mediators that could con
Externí odkaz:
https://doaj.org/article/ba508f831c544ce9bec9226ec64d6597
Autor:
Anne-Mari Mustonen, Reijo Käkelä, Mikko A. J. Finnilä, Andrew Sawatsky, Rami K. Korhonen, Simo Saarakkala, Walter Herzog, Tommi Paakkonen, Petteri Nieminen
Publikováno v:
Lipids in Health and Disease, Vol 18, Iss 1, Pp 1-9 (2019)
Abstract Background The infrapatellar fat pad (IFP) of the knee joint has received lots of attention recently due to its emerging role in the pathogenesis of osteoarthritis (OA), where it displays an inflammatory phenotype. The aim of the present stu
Externí odkaz:
https://doaj.org/article/604fcb8d45e44afdb9eb4a6a921a5648
Publikováno v:
Reproductive Health, Vol 14, Iss 1, Pp 1-12 (2017)
Abstract Background The ethical discussion about abortion has been polarized in Finland and the Republic of Ireland, two European countries with very different abortion legislation (liberal vs. highly restrictive). The aim of the present study was to
Externí odkaz:
https://doaj.org/article/cd73cf6aa4ac4c1e9f7d210cfcf4b695
Autor:
Anne-Mari Mustonen, Reijo Käkelä, Antti Joukainen, Petri Lehenkari, Antti Jaroma, Tommi Kääriäinen, Heikki Kröger, Tommi Paakkonen, Sanna P. Sihvo, Petteri Nieminen
Publikováno v:
Biology, Vol 10, Iss 5, p 401 (2021)
Anomalies of fatty acid (FA) metabolism characterize osteoarthritis (OA) and rheumatoid arthritis (RA) in the knee joint. No previous study has investigated the synovial fluid (SF) FA manifestations in these aging-related inflammatory diseases in the
Externí odkaz:
https://doaj.org/article/e335db08bd034f379a763037d0828669
Autor:
Petteri Nieminen, Wilhelmiina Hämäläinen, Juha Savinainen, Marko Lehtonen, Saara Lehtiniemi, Juho Rinta-Paavola, Petri Lehenkari, Tommi Kääriäinen, Antti Joukainen, Heikki Kröger, Tommi Paakkonen, Anne-Mari Mustonen
Funding Information: Open access funding provided by University of Eastern Finland (UEF) including Kuopio University Hospital. Financial support for the study was provided by the Academy of Finland (grant #322429 to PN). The funding source had no inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4ff67e9f5ec4e35fc0c3ba175791b5
https://aaltodoc.aalto.fi/handle/123456789/114564
https://aaltodoc.aalto.fi/handle/123456789/114564
Autor:
Anne-Mari Mustonen, Tommi Paakkonen, Johanna Matilainen, Kirsi Rilla, Reijo Käkelä, Marjo Malinen, Piia Takabe, Sanna Oikari, Janne Capra, Sanna P. Sihvo, Pauliina Ryökäs, Petteri Nieminen
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5613
Extracellular vesicles (EVs) function as conveyors of fatty acids (FAs) and other bioactive lipids and can modulate the gene expression and behavior of target cells. EV lipid composition influences the fluidity and stability of EV membranes and refle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa22e4a7f33fc303a3b42efc4e6fbdf
https://pubmed.ncbi.nlm.nih.gov/35628422
https://pubmed.ncbi.nlm.nih.gov/35628422