Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tommi Manninen"'
Autor:
Pentti Tuohimaa, Jing-Huan Wang, Sofia Khan, Marianne Kuuslahti, Kui Qian, Tommi Manninen, Petri Auvinen, Mauno Vihinen, Yan-Ru Lou
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75338 (2013)
1α,25-Dihydroxyvitamin D3 (1α,25(OH)2D3) had earlier been regarded as the only active hormone. The newly identified actions of 25-hydroxyvitamin D3 (25(OH)D3) and 24R,25-dihydroxyvitamin D3 (24R,25(OH)2D3) broadened the vitamin D3 endocrine system,
Externí odkaz:
https://doaj.org/article/b2d268de62594e819e74d23a0bc30cb4
Autor:
Pentti Tuohimaa, Jing-Huan Wang, Sofia Khan, Marianne Kuuslahti, Kui Qian, Tommi Manninen, Petri Auvinen, Mauno Vihinen, Yan-Ru Lou
Publikováno v:
PLoS ONE, Vol 8, Iss 11 (2013)
Externí odkaz:
https://doaj.org/article/326b9ab886264b53b0331af2f712b682
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 96:13-18
The ubiquitous heat shock protein 90 (hsp90) has been shown to participate directly in the function of a wide variety of cellular signal transduction components, including steroid receptors (SRs). However, there is still no direct evidence for an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c570c9b8f35afa1111eea90d1ca905a
https://doi.org/10.1016/j.jsbmb.2004.12.048
https://doi.org/10.1016/j.jsbmb.2004.12.048
Autor:
Heimo Syvälä, Yan-Ru Lou, Merja H. Ahonen, Pentti Tuohimaa, Timo Ylikomi, Tommi Manninen, Susanna Miettinen
Publikováno v:
International Journal of Cancer. 108:367-373
Vitamin D and its analogues are potent regulators of cell growth and differentiation both in vivo and in vitro. We studied the effects of 25-hydroxyvitamin D(3) [25(OH)D(3)], 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] and vitamin D analogue, EB 108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b57a13f04fe2570911faf94e3a81da94
https://doi.org/10.1002/ijc.11520
https://doi.org/10.1002/ijc.11520
Publikováno v:
Endocrinology. 143:4620-4626
We have previously shown that the G protein-coupled receptor (GPR)30 is critical for progestin-induced growth inhibition. In this study, we addressed signal transduction pathways involved in progestin-mediated signaling. Progestin could not provide a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cd640d9a17a7449d226a090ee783d9
https://doi.org/10.1210/en.2002-220492
https://doi.org/10.1210/en.2002-220492
Publikováno v:
Endocrinology. 143:3376-3384
The issue of how progesterone affects mammary gland growth is controversial, and the mechanism governing the effects of the hormone remains mostly unknown. We have previously shown that G protein-coupled receptor 30 (GPR30) is a progestin target gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a7087f7bef9bd5493f7d833c1af728
https://doi.org/10.1210/en.2001-211445
https://doi.org/10.1210/en.2001-211445
Publikováno v:
European Journal of Biochemistry. 268:5337-5342
With some exceptions, research so far has shown heat shock protein (Hsp) 90 to be a cytoplasmic protein. Here, we studied the sequence determinants which dictate the subcellular localization of Hsp90. By constructing hybrid molecules between a nuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf9b464ef3be7dde4cb938e66ae79f9e
https://doi.org/10.1046/j.0014-2956.2001.02467.x
https://doi.org/10.1046/j.0014-2956.2001.02467.x
Autor:
Pekka Vilja, Yan-Ru Lou, T Hasan, Susanna Miettinen, Timo Ylikomi, Pasi Pennanen, N Aksenov, P Pasanen, Pentti Tuohimaa, Merja Bläuer, Heimo Syvälä, Alex Lyakhovich, Tommi Manninen, Merja H. Ahonen
Publikováno v:
University of Helsinki
Our recent epidemiological study (Ahonen et al., Cancer Causes Control 11(2000) (847-852)) suggests that vitamin D deficiency may increase the risk of initiation and progression of prostate cancer. The nested case-control study was based on a 13-year
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24f2f2bdd62946016ea2f40494f8987
https://doi.org/10.1016/s0960-0760(00)00141-2
https://doi.org/10.1016/s0960-0760(00)00141-2
Autor:
Kui Qian, Yan-Ru Lou, Jing-Huan Wang, Sofia Khan, Mauno Vihinen, Pentti Tuohimaa, Marianne Kuuslahti, Tommi Manninen, Petri Auvinen
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75338 (2013)
PLoS ONE
PLoS ONE; 8(10), no e75338 (2013)
PLoS ONE
PLoS ONE; 8(10), no e75338 (2013)
1 alpha,25-Dihydroxyvitamin D-3 (1 alpha,25(OH)(2)D-3) had earlier been regarded as the only active hormone. The newly identified actions of 25-hydroxyvitamin D-3 (25(OH)D-3) and 24R,25-dihydroxyvitamin D-3 (24R,25(OH)(2)D-3) broadened the vitamin D-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661eb35e94ac24d6a8edfa98fca92202
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24116037/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24116037/pdf/?tool=EBI
Publikováno v:
Oncology reports. 19(6)
Sex steroid hormone progesterone is known to have profound effects on the growth and differentiation of the normal mammary gland and malignant breast epithelial cells. In vitro progesterone and synthetic progesterone-like compounds (progestins) inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec027db47ea2abafcceca6c47de4158b
https://pubmed.ncbi.nlm.nih.gov/18497975
https://pubmed.ncbi.nlm.nih.gov/18497975