Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Tommaso A Dragani"'
Autor:
Matteo Dugo, Chiara E Cotroneo, Emilie Lavoie-Charland, Matteo Incarbone, Luigi Santambrogio, Lorenzo Rosso, Maarten van den Berge, David Nickle, Peter D Paré, Yohan Bossé, Tommaso A Dragani, Francesca Colombo
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167460 (2016)
Sex and age strongly influence the pathophysiology of human lungs, but scarce information is available about their effects on pulmonary gene expression.We followed a discovery-validation strategy to identify sex- and age-related transcriptional diffe
Externí odkaz:
https://doaj.org/article/730f9ecf9f5c484a9c0bc521d0c1e3c9
Autor:
Martina Esposito, Francesca Minnai, Massimiliano Copetti, Giuseppe Miscio, Rita Perna, Ada Piepoli, Gabriella De Vincentis, Mario Benvenuto, Paola D’Addetta, Susanna Croci, Margherita Baldassarri, Mirella Bruttini, Chiara Fallerini, Raffaella Brugnoni, Paola Cavalcante, Fulvio Baggi, Elena Maria Grazia Corsini, Emilio Ciusani, Francesca Andreetta, Tommaso A. Dragani, Maddalena Fratelli, Massimo Carella, Renato E. Mantegazza, Alessandra Renieri, Francesca Colombo
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-7 (2024)
Abstract Background Since the beginning of the anti-COVID-19 vaccination campaign, it has become evident that vaccinated subjects exhibit considerable inter-individual variability in the response to the vaccine that could be partly explained by host
Externí odkaz:
https://doaj.org/article/f2ddf483171b44c8a0f1ce4d0ef108aa
Autor:
Francesca Minnai, Filippo Biscarini, Martina Esposito, Tommaso A. Dragani, Luis Bujanda, Souad Rahmouni, Marta E. Alarcón-Riquelme, David Bernardo, Elena Carnero-Montoro, Maria Buti, Hugo Zeberg, Rosanna Asselta, Manuel Romero-Gómez, GEN-COVID Multicenter Study, Israel Fernandez-Cadenas, Chiara Fallerini, Kristina Zguro, Susanna Croci, Margherita Baldassarri, Mirella Bruttini, Simone Furini, Alessandra Renieri, Francesca Colombo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The clinical manifestations of SARS-CoV-2 infection vary widely among patients, from asymptomatic to life-threatening. Host genetics is one of the factors that contributes to this variability as previously reported by the COVID-19 Host Genet
Externí odkaz:
https://doaj.org/article/720db8359dd141d598d5bfa82cb29689
Autor:
Alice Dassano, Francesca Colombo, Gaia Trincucci, Elisa Frullanti, Antonella Galvan, Angela Pettinicchio, Loris De Cecco, Andrea Borrego, Olga Célia Martinez Ibañez, Tommaso A Dragani, Giacomo Manenti
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004307 (2014)
Pulmonary adenoma susceptibility 1 (Pas1) is the major locus responsible for lung tumor susceptibility in mice; among the six genes mapping in this locus, Kras is considered the best candidate for Pas1 function although how it determines tumor suscep
Externí odkaz:
https://doaj.org/article/94dc640eaf5c413589929d533828b21e
Autor:
Marcelo De Franco, Luciana C Peters, Mara A Correa, Antonella Galvan, Tatiane Canhamero, Andrea Borrego, José R Jensen, Jussara Gonçalves, Wafa H K Cabrera, Nancy Starobinas, Orlando G Ribeiro, Tommaso A Dragani, Olga M Ibañez
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88302 (2014)
AIRmax (maximal inflammation) and AIRmin (minimal inflammation) mice show distinct susceptibilities to pristane-induced arthritis (PIA). The Slc11a1 gene, which regulates macrophage and neutrophil activity, is involved in this infirmity. AIRmax (SS)
Externí odkaz:
https://doaj.org/article/bc537b0914ba49758abf3f72e08c409f
Autor:
Giacomo Manenti, Antonella Galvan, Angela Pettinicchio, Gaia Trincucci, Elena Spada, Anna Zolin, Silvano Milani, Anna Gonzalez-Neira, Tommaso A Dragani
Publikováno v:
PLoS Genetics, Vol 5, Iss 1, p e1000331 (2009)
We carried out genome-wide association (GWA) studies in inbred mouse strains characterized for their lung tumor susceptibility phenotypes (spontaneous or urethane-induced) with panels of 12,959 (13K) or 138,793 (140K) single-nucleotide polymorphisms
Externí odkaz:
https://doaj.org/article/e8568445cf6046c6a27ff2e8e1f08343
Autor:
Francesca Spyrakis, Tommaso A. Dragani
Publikováno v:
Toxics, Vol 11, Iss 9, p 721 (2023)
The proposal by the European Chemicals Agency (ECHA) to ban over 12,000 per- and polyfluoroalkyl substances (PFAS) has sparked a debate about potential consequences for the economy, industry, and the environment. Although some PFAS are known to be ha
Externí odkaz:
https://doaj.org/article/2380439093da4050b67cdfcfa0305cbe
Autor:
Tommaso A. Dragani, Thomas Muley, Marc A. Schneider, Sonja Kobinger, Martin Eichhorn, Hauke Winter, Hans Hoffmann, Mark Kriegsmann, Sara Noci, Matteo Incarbone, Davide Tosi, Sara Franzi, Francesca Colombo
Publikováno v:
Cancers, Vol 15, Iss 8, p 2395 (2023)
To date, the factors which affect the age at diagnosis of lung adenocarcinoma are not fully understood. In our study, we examined the relationships of age at diagnosis with smoking, pathological stage, sex, and year of diagnosis in a discovery (n = 1
Externí odkaz:
https://doaj.org/article/aa16d55514a0465fb34dbe96e9339570
Autor:
Francesca Minnai, Sara Noci, Marco Chierici, Chiara Elisabetta Cotroneo, Barbara Bartolini, Matteo Incarbone, Davide Tosi, Giovanni Mattioni, Giuseppe Jurman, Tommaso A. Dragani, Francesca Colombo
Publikováno v:
Cancer Science. 114:281-294
Emerging evidence suggests that the prognosis of patients with lung adenocarcinoma can be determined from germline variants and transcript levels in nontumoral lung tissue. Gene expression data from noninvolved lung tissue of 483 lung adenocarcinoma
Autor:
Lilian Rego de Carvalho, Andrea Borrego, José Ricardo Jensen, Wafa Hanna Koury Cabrera, Aline Marques Santos, Orlando Garcia Ribeiro, Nancy Starobinas, Marcelo De Franco, Tommaso A. Dragani, Giacomo Manenti, Olga Célia Martinez Ibañez
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
AIRmax and AIRmin mouse strains phenotypically selected for high and low acute inflammatory responsiveness (AIR) are, respectively, susceptible or resistant to developing hepatocellular carcinoma (HCC) induced by the chemical carcinogens urethane and
Externí odkaz:
https://doaj.org/article/d765b78cd97c4e58a7d751dc24b0d83b