Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Tommaso, Pizzorusso"'
Autor:
Elsa Ghirardini, Giulia Sagona, Angel Marquez-Galera, Francesco Calugi, Carmen M. Navarron, Francesco Cacciante, Siwei Chen, Federica Di Vetta, Lorenzo Dadà, Raffaele Mazziotti, Leonardo Lupori, Elena Putignano, Pierre Baldi, Jose P. Lopez-Atalaya, Tommaso Pizzorusso, Laura Baroncelli
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Mutations in the solute carrier family 6-member 8 (Slc6a8) gene, encoding the protein responsible for cellular creatine (Cr) uptake, cause Creatine Transporter Deficiency (CTD), an X-linked neurometabolic disorder presenting with intellectua
Externí odkaz:
https://doaj.org/article/3f49e5cb2fdd44aa8c6228ed37b9bcba
Autor:
Leonardo Lupori, Valentino Totaro, Sara Cornuti, Luca Ciampi, Fabio Carrara, Edda Grilli, Aurelia Viglione, Francesca Tozzi, Elena Putignano, Raffaele Mazziotti, Giuseppe Amato, Claudio Gennaro, Paola Tognini, Tommaso Pizzorusso
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112788- (2023)
Summary: Perineuronal nets (PNNs) surround specific neurons in the brain and are involved in various forms of plasticity and clinical conditions. However, our understanding of the PNN role in these phenomena is limited by the lack of highly quantitat
Externí odkaz:
https://doaj.org/article/281e08c3d41a4e19b35de18cf9af6500
Publikováno v:
Frontiers in Neural Circuits, Vol 17 (2023)
Pupil size variations have been associated with changes in brain activity patterns related with specific cognitive factors, such as arousal, attention, and mental effort. The locus coeruleus (LC), a key hub in the noradrenergic system of the brain, i
Externí odkaz:
https://doaj.org/article/04e71fbd807043f2a7efbfe53b672678
A survey of the latest research, covering such topics as plasticity in the adult brain and the underlying mechanisms of plasticity. The notion that neurons in the living brain can change in response to experience—a phenomenon known as'plasticity'
Autor:
Andrea Poli, Aurelia Viglione, Raffaele Mazziotti, Valentino Totaro, Silvia Morea, Riccardo Melani, Davide Silingardi, Elena Putignano, Nicoletta Berardi, Tommaso Pizzorusso
Publikováno v:
Molecular Neurobiology. 60:4105-4119
The ability to store, retrieve, and extinguish memories of adverse experiences is an essential skill for animals’ survival. The cellular and molecular factors that underlie such processes are only partially known. Using chondroitinase ABC treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f737414755b06387195ceb4af0cb468
https://doi.org/10.1007/s12035-023-03314-x
https://doi.org/10.1007/s12035-023-03314-x
Autor:
Raffaele Mazziotti, Laura Baroncelli, Nicholas Ceglia, Gabriele Chelini, Grazia Della Sala, Christophe Magnan, Debora Napoli, Elena Putignano, Davide Silingardi, Jonida Tola, Paola Tognini, J. Simon C. Arthur, Pierre Baldi, Tommaso Pizzorusso
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
miR-132/212 has been implicated in ocular dominance plasticity during the critical period. Here the authors show that miR-132/212 regulates the expression of genes involved in visual cortex maturation, and that mice lack miR-132/212 show deficits in
Externí odkaz:
https://doaj.org/article/5888fc985dda4b93a052f3e04b218072
Autor:
Antonia Gurgone, Riccardo Pizzo, Alessandra Raspanti, Giuseppe Chiantia, Sunaina Devi, Debora Comai, Noemi Morello, Federica Pilotto, Sara Gnavi, Leonardo Lupori, Raffaele Mazziotti, Giulia Sagona, Elena Putignano, Alessio Nocentini, Claudiu T. Supuran, Andrea Marcantoni, Tommaso Pizzorusso, Maurizio Giustetto
Publikováno v:
Neuropsychopharmacology. 48:877-886
Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a devastating rare neurodevelopmental disease without a cure, caused by mutations of the serine/threonine kinase CDKL5 highly expressed in the forebrain. CDD is characterized by earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27452c5573b5e237671a749ad3518ed3
https://doi.org/10.1038/s41386-022-01412-3
https://doi.org/10.1038/s41386-022-01412-3
Publikováno v:
Neural Plasticity, Vol 2019 (2019)
Cerebral ischemia can occur at any stage in life, but clinical consequences greatly differ depending on the developmental stage of the affected brain structures. Timing of the lesion occurrence seems to be critical, as it strongly interferes with neu
Externí odkaz:
https://doaj.org/article/a941880926a1497e96cef930228beb8e
Autor:
Giulia Faini, Andrea Aguirre, Silvia Landi, Didi Lamers, Tommaso Pizzorusso, Gian Michele Ratto, Charlotte Deleuze, Alberto Bacci
Publikováno v:
eLife, Vol 7 (2018)
In the neocortex, critical periods (CPs) of plasticity are closed following the accumulation of perineuronal nets (PNNs) around parvalbumin (PV)-positive inhibitory interneurons. However, how PNNs tune cortical function and plasticity is unknown. We
Externí odkaz:
https://doaj.org/article/cce9e2eb04654fafbfe655ffe2b5a094