Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tomlinson, JH"'
Autor:
Gupta, A, Monteferrante, C, Rasina, D, Leitis, G, Randall, CP, Tomlinson, JH, Jirgensons, A, Goessens, WHF, Hays, JP, O'Neill, AJ
GSK2251052 is a broad-spectrum antibacterial inhibitor of leucyl tRNA-synthetase (LeuRS) that has been evaluated in Phase II clinical trials. Here we report the identification of a clinical isolate of Staphylococcus aureus that exhibits reduced susce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::81faca4bc1891e0c427f9dc1c33da3c1
Akademický článek
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Autor:
Oslund RC; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA. rob@induprolabs.com.; InduPro, Cambridge, MA, USA. rob@induprolabs.com., Reyes-Robles T; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA. tamara.reyes.robles@merck.com., White CH; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA., Tomlinson JH; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA., Crotty KA; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA., Bowman EP; Discovery Research, Merck & Co., Inc., San Francisco, CA, USA., Chang D; Genetics and Pharmacogenomics, Merck & Co., Inc., Boston, MA, USA., Peterson VM; Genetics and Pharmacogenomics, Merck & Co., Inc., Boston, MA, USA., Li L; Genetics and Pharmacogenomics, Merck & Co., Inc., Boston, MA, USA., Frutos S; SpliceBio, Barcelona, Spain., Vila-Perelló M; SpliceBio, Barcelona, Spain., Vlerick D; Ablynx, A Sanofi Company, Zwijnaarde, Belgium., Cromie K; Ablynx, A Sanofi Company, Zwijnaarde, Belgium., Perlman DH; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA., Ingale S; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA., Hara SDO; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA., Roberts LR; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA., Piizzi G; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA., Hett EC; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA., Hazuda DJ; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA.; Infectious Diseases and Vaccine Research, Merck & Co., Inc., West Point, PA, USA., Fadeyi OO; Merck Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA. niyi@induprolabs.com.; InduPro, Cambridge, MA, USA. niyi@induprolabs.com.
Publikováno v:
Nature chemical biology [Nat Chem Biol] 2022 Aug; Vol. 18 (8), pp. 850-858. Date of Electronic Publication: 2022 Jun 02.
Autor:
Bissonnette NB; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA., Ryu KA; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA., Reyes-Robles T; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA., Wilhelm S; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA., Tomlinson JH; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA., Crotty KA; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA., Hett EC; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA., Roberts LR; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA., Hazuda DJ; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA.; Infectious Diseases and Vaccine Research, Merck & Co., Inc. Merck Research Laboratories, West Point, PA 19486, USA., Jared Willis M; Efficieny Aggregators, 1207 FM 359, Richmond, TX 77406, USA., Oslund RC; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA., Fadeyi OO; Exploratory Science Center, Merck & Co., Inc., 320 Bent Street, Cambridge, MA 02141, USA.
Publikováno v:
Chembiochem : a European journal of chemical biology [Chembiochem] 2020 Dec 11; Vol. 21 (24), pp. 3555-3562. Date of Electronic Publication: 2020 Sep 16.
Autor:
Tomlinson JH; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT Leeds, United Kingdom; j.h.tomlinson@leeds.ac.uk.; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT Leeds, United Kingdom., Kalverda AP; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT Leeds, United Kingdom.; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT Leeds, United Kingdom., Calabrese AN; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT Leeds, United Kingdom.; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT Leeds, United Kingdom.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Oct 13; Vol. 117 (41), pp. 25523-25531. Date of Electronic Publication: 2020 Sep 30.
Autor:
Tomlinson JH; Department of Anaesthesia, Northwick Park Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK. Electronic address: jhgrey@doctors.org.uk., Lucas DN; Department of Anaesthesia, Northwick Park Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK. Electronic address: nuala.lucas@nhs.net.
Publikováno v:
Best practice & research. Clinical anaesthesiology [Best Pract Res Clin Anaesthesiol] 2017 Mar; Vol. 31 (1), pp. 49-56. Date of Electronic Publication: 2017 Apr 25.
Autor:
Tomlinson JH; Department of Critical Care, University College Hospital, T03, 3RD floor, 235 Euston Road, London, NW1 2BU UK., Partridge JS; Proactive care of Older People undergoing Surgery (POPS), Department of Ageing and Health, St Thomas' Hospital, 9th Floor North Wing, Westminster Bridge Road, London, SE1 7EH UK.
Publikováno v:
Perioperative medicine (London, England) [Perioper Med (Lond)] 2016 Sep 01; Vol. 5 (1), pp. 22. Date of Electronic Publication: 2016 Sep 01 (Print Publication: 2016).
Autor:
Tomlinson JH; Department of Anaesthesia and Intensive Care, Chelsea and Westminster Hospital, London, UK., Shah SV; Department of Anaesthesia and Intensive Care, Chelsea and Westminster Hospital, London, UK., Vizcaychipi MP; Department of Anaesthesia and Intensive Care, Chelsea and Westminster Hospital, London, UK.
Publikováno v:
Journal of the Intensive Care Society [J Intensive Care Soc] 2016 May; Vol. 17 (2), pp. 171-174. Date of Electronic Publication: 2015 Oct 29.