ClC-Kb pore mutation disrupts glycosylation and triggers distal tubular remodeling.

Autor: Sharma Y; Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Lo R; Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Tomilin VN; Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas, USA., Ha K; Department of Physiology, UCSF, San Francisco, California, USA., Deremo H; Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Pareek AV; Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Dong W; Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Liao X; Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Lebedeva S; Department of Pharmacology, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Moscow, Russia., Charu V; Department of Pathology, Stanford University School of Medicine, Stanford, California, USA., Kambham N; Department of Pathology, Stanford University School of Medicine, Stanford, California, USA., Mutig K; Department of Pharmacology, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.; Department of Translational Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany., Pochynyuk O; Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas, USA., Bhalla V; Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.

Publikováno v: JCI insight [JCI Insight] 2024 Nov 22; Vol. 9 (22). Date of Electronic Publication: 2024 Nov 22.

TRPV4 expression in the renal tubule is necessary for maintaining whole body K ⁺ homeostasis.

Autor: Stavniichuk A; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States., Pyrshev K; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States., Zaika O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States., Tomilin VN; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States., Kordysh M; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States., Lakk M; Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, Utah, United States., Križaj D; Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, Utah, United States., Pochynyuk O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.

Publikováno v: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2023 Jun 01; Vol. 324 (6), pp. F603-F616. Date of Electronic Publication: 2023 May 04.

Modus operandi of ClC-K2 Cl ^- Channel in the Collecting Duct Intercalated Cells.

Autor: Stavniichuk A; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Pyrshev K; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Tomilin VN; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Kordysh M; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Zaika O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Pochynyuk O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

Publikováno v: Biomolecules [Biomolecules] 2023 Jan 14; Vol. 13 (1). Date of Electronic Publication: 2023 Jan 14.

Epac1-/- and Epac2-/- mice exhibit deficient epithelial Na+ channel regulation and impaired urinary Na+ conservation.

Autor: Tomilin VN; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Pyrshev K; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Stavniichuk A; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Hassanzadeh Khayyat N; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Ren G; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Zaika O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Khedr S; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.; Department of Physiology, Faculty of Medicine, Ain-Shams University, Cairo, Egypt., Staruschenko A; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.; Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, USA., Mei FC; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Cheng X; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Pochynyuk O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

Publikováno v: JCI insight [JCI Insight] 2022 Feb 08; Vol. 7 (3). Date of Electronic Publication: 2022 Feb 08.

With-No-Lysine Kinase 1 (WNK1) Augments TRPV4 Function in the Aldosterone-Sensitive Distal Nephron.

Autor: Tomilin VN; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, 6431 Fannin, Houston, TX 77030, USA., Pyrshev K; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, 6431 Fannin, Houston, TX 77030, USA., Khayyat NH; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, 6431 Fannin, Houston, TX 77030, USA., Zaika O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, 6431 Fannin, Houston, TX 77030, USA., Pochynyuk O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, 6431 Fannin, Houston, TX 77030, USA.

Publikováno v: Cells [Cells] 2021 Jun 12; Vol. 10 (6). Date of Electronic Publication: 2021 Jun 12.