Zobrazeno 1 - 10
of 812
pro vyhledávání: '"Tomi K"'
Autor:
Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G. Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra S. Verma, David P. Lane, Tomi K. Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J. Brown, Charles W. Johannes, Anthony W. Partridge
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Although stapled α-helical peptides can address challenging targets, their advancement is impeded by poor understandings for making them cell permeable while avoiding off-target toxicities. By synthesizing >350 molecules, we present workflo
Externí odkaz:
https://doaj.org/article/244b34e3aef44b508696598d0927724f
Autor:
Anton V. Malyshev, Vsevolod V. Pavshintcev, Nikita A. Mitkin, Iuliia A. Sukhanova, Vasilina R. Gedzun, Alexander S. Zlobin, Igor I. Doronin, Gennady A. Babkin, Tomi K. Sawyer
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
We employed a structural bioinformatics approach to develop novel peptides with predicted affinity to the binding site for negative allosteric modulators (NAMs) of metabotropic glutamate receptor 5 (mGluR5). Primary screening in zebrafish (Danio reri
Externí odkaz:
https://doaj.org/article/76cf2f54874a4026980726e84e360222
Autor:
Jarno T. Huhtanen, Mikko Nyman, Dorin Doncenco, Maral Hamedian, Davis Kawalya, Leena Salminen, Roberto Blanco Sequeiros, Seppo K. Koskinen, Tomi K. Pudas, Sami Kajander, Pekka Niemi, Jussi Hirvonen, Hannu J. Aronen, Mojtaba Jafaritadi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Joint effusion due to elbow fractures are common among adults and children. Radiography is the most commonly used imaging procedure to diagnose elbow injuries. The purpose of the study was to investigate the diagnostic accuracy of deep convo
Externí odkaz:
https://doaj.org/article/46c3d43e8a4347e0bae0860e83a5cb23
Autor:
Jarno T. Huhtanen, Mikko Nyman, Roberto Blanco Sequeiros, Seppo K. Koskinen, Tomi K. Pudas, Sami Kajander, Pekka Niemi, Eliisa Löyttyniemi, Hannu J. Aronen, Jussi Hirvonen
Publikováno v:
Diagnostics, Vol 13, Iss 20, p 3207 (2023)
(1) Background: The aim of this study was to compare the competence in appendicular trauma radiograph image interpretation between radiology specialists and residents. (2) Methods: In this multicenter retrospective cohort study, we collected radiolog
Externí odkaz:
https://doaj.org/article/8d56da14ff7449c4a3bd3898a11e60c3
Autor:
Nagaya, Narumi, Lee, Kangmin, Perkinson, Collin F., Li, Aaron, Lee, Youri, Zhong, Xinjue, Lee, Sujin, Weisburn, Leah P., Baikie, Tomi K., Bawendi, Moungi G., Van Voorhis, Troy, Tisdale, William A., Kahn, Antoine, Seo, Kwanyong, Baldo, Marc A.
While silicon solar cells dominate global photovoltaic energy production, their continued improvement is hindered by the single junction limit. One potential solution is to use molecular singlet exciton fission to generate two electrons from each abs
Externí odkaz:
http://arxiv.org/abs/2407.21093
Publikováno v:
PRX Energy, Vol 1, Iss 3, p 033001 (2022)
Luminescent solar concentrators (LSCs) are theoretically able to concentrate both direct and diffuse solar radiation with extremely high efficiencies. Photon-multiplier luminescent solar concentrators (PM-LSCs) contain chromophores that exceed 100% p
Externí odkaz:
https://doaj.org/article/f3459412aa814c6089bb74973b9a604b
Autor:
Richard V. Lundell, Anne K. Räisänen-Sokolowski, Tomi K. Wuorimaa, Tommi Ojanen, Kai I. Parkkola
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
IntroductionDiving close to the Arctic circle means diving in cold water regardless of the time of year. The human body reacts to cold through autonomous nervous system (ANS)-mediated thermoregulatory mechanisms. Diving also induces ANS responses as
Externí odkaz:
https://doaj.org/article/bbead21cd3a84c8e9d62946003329805
Autor:
Baikie, Tomi K., Kosmützky, Darius, Lawrence, Joshua M., Gray, Victor, Schnedermann, Christoph, Horton, Robin, Collins, Joel D., Medipally, Hitesh, Witek, Bartosz, Nowaczyk, Marc M., Zhang, Jenny, Wey, Laura, Howe, Christopher J., Rao, Akshay
Transient absorption (TA) spectroscopy has proved fundamental to our understanding of energy and charge transfer in biological systems, allowing measurements of photoactive proteins on sub-picosecond timescales. Recently, ultrafast TA spectroscopy ha
Externí odkaz:
http://arxiv.org/abs/2307.09448
Autor:
Baikie, Tomi K., Calado, Philip, Galkowski, Krzysztof, Andaji-Garmaroudi, Zahra, Chin, Yi-Chun, Luke, Joel, Henderson, Charlie, Dunlop, Tom, McGettrick, James, Kim, Ji-Seon, Rao, Akshay, Nelson, Jenny, Stranks, Samuel D., Barnes, Piers R. B.
Metal halide perovskite solar cells have gained widespread attention due to their high efficiency and high defect tolerance. The absorbing perovskite layer is as a mixed electron-ion conductor that supports high rates of ion and charge transport at r
Externí odkaz:
http://arxiv.org/abs/2305.14942
Luminescent solar concentrators (LSCs) are able to concentrate both direct and diffuse solar radiation and this ability has led to great interest in using them to improve solar energy capture when coupled to traditional photovoltaics (PV). In princip
Externí odkaz:
http://arxiv.org/abs/2303.17411