Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Tomi Ivacevic"'
1
Akademický článek
Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation and differentiation in vivo.
Autor: Mónica Costa, Eugénia Cruz, Susana Oliveira, Vladimir Benes, Tomi Ivacevic, Maria João Silva, Inês Vieira, Francisco Dias, Sónia Fonseca, Marta Gonçalves, Margarida Lima, Catarina Leitão, Martina U Muckenthaler, Jorge Pinto, Graça Porto
Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0124246 (2015)
Abnormally low CD8+ T-lymphocyte numbers is characteristic of some patients with hereditary hemochromatosis (HH), a MHC-linked disorder of iron overload. Both environmental and genetic components are known to influence CD8+ T-lymphocyte homeostasis b
Externí odkaz: https://doaj.org/article/f460662d2e664256b3276fa3a200f11a
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2
Akademický článek
Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis.
Autor: Guillaume Suffert, Georg Malterer, Jean Hausser, Johanna Viiliäinen, Aurélie Fender, Maud Contrant, Tomi Ivacevic, Vladimir Benes, Frédéric Gros, Olivier Voinnet, Mihaela Zavolan, Päivi M Ojala, Juergen G Haas, Sébastien Pfeffer
Publikováno v: PLoS Pathogens, Vol 7, Iss 12, p e1002405 (2011)
Kaposi's sarcoma herpesvirus (KSHV) encodes a cluster of twelve micro (mi)RNAs, which are abundantly expressed during both latent and lytic infection. Previous studies reported that KSHV is able to inhibit apoptosis during latent infection; we thus t
Externí odkaz: https://doaj.org/article/3e1319a9b25b4d58809a8612eb7109b1
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3
Akademický článek
Thyrotroph embryonic factor regulates light-induced transcription of repair genes in zebrafish embryonic cells.
Autor: Daria Gavriouchkina, Sabine Fischer, Tomi Ivacevic, Jens Stolte, Vladimir Benes, Marcus P S Dekens
Publikováno v: PLoS ONE, Vol 5, Iss 9, p e12542 (2010)
Numerous responses are triggered by light in the cell. How the light signal is detected and transduced into a cellular response is still an enigma. Each zebrafish cell has the capacity to directly detect light, making this organism particularly suita
Externí odkaz: https://doaj.org/article/b769ab2301604bfbbb0dc97a01225f04
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4
Importin 8 Is a Gene Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs
Autor: Jörg Mütze, Elisabeth Kremmer, Gunter Meister, Petra Schwille, Tomi Ivacevic, Thomas Ohrt, Lasse Weinmann, Julia Höck, Henning Urlaub, Vladimir Benes
Publikováno v: Cell
SUMMARY Small regulatory RNAs including small interfering RNAs (siRNAs) and microRNAs (miRNAs) guide Argonaute (Ago) proteins to specific target RNAs leading to mRNA destabilization or translational repression. Here, we report the identification of I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7295fad6714e8e194c6ffbe934c18a
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5
Upregulation of Soluble Vascular Endothelial Growth Factor Receptor 1 Contributes to Angiogenesis Defects in the Placenta of α 2B -Adrenoceptor–Deficient Mice
Autor: Manfred Gessler, Miriam Haubold, Lutz Hein, Tomi Ivacevic, Melanie Philipp, Ralf Gilsbach, Verena Muthig
Publikováno v: Circulation Research. 101:682-691
α 2 -adrenoceptors are essential presynaptic regulators of norepinephrine release from sympathetic nerves. Previous studies in mice with targeted deletions in the 3 α 2 -adrenoceptor genes have indicated that these receptors are essential for embry
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3151e547f6189a01b924266f78a5a36c
https://doi.org/10.1161/circresaha.107.151563
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6
Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation and differentiation in vivo
Autor: Tomi Ivacevic, Vladimir Benes, Sónia Fonseca, J. E. B. P. Pinto, Francisco Dias, Mónica Costa, Inês Vieira, Maria João Silva, Martina U. Muckenthaler, Graça Porto, Eugénia Cruz, Catarina Leitão, Marta Gonçalves, Susana Oliveira, Margarida Lima
Publikováno v: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
PLoS ONE, Vol 10, Iss 4, p e0124246 (2015)
PLoS ONE
Abnormally low CD8+ T-lymphocyte numbers is characteristic of some patients with hereditary hemochromatosis (HH), a MHC-linked disorder of iron overload. Both environmental and genetic components are known to influence CD8+ T-lymphocyte homeostasis b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b3a257df4818532a0b4569d142c8c7
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7
Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor α, in response to deacetylase inhibition by valproic acid and trichostatin A
Autor: Heike Brand, Raphaël Métivier, Edison T. Liu, Vladimir Benes, Chin-Yo Lin, Stefanie Denger, Tomi Ivacevic, Frank Gannon, George Reid, David Ibberson
Publikováno v: Oncogene. 24:4894-4907
Valproate (VPA) and trichostatin A (TSA), inhibitors of zinc-dependent deacetylase activity, induce reduction in the levels of mRNA encoding oestrogen receptor-alpha (ERalpha), resulting in subsequent clearance of ERalpha protein from breast and ovar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46cbe1e28e072956fae53718a41dd3c
https://doi.org/10.1038/sj.onc.1208662
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8
Thyrotroph embryonic factor regulates light-induced transcription of repair genes in zebrafish embryonic cells
Autor: Tomi Ivacevic, Vladimir Benes, Daria Gavriouchkina, Marcus P. S. Dekens, Sabine C. Fischer, Jens Stolte
Publikováno v: PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12542 (2010)
Numerous responses are triggered by light in the cell. How the light signal is detected and transduced into a cellular response is still an enigma. Each zebrafish cell has the capacity to directly detect light, making this organism particularly suita
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f944c33c89d3e3a1472074cac779fb
https://pubmed.ncbi.nlm.nih.gov/20830285
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