Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tomer Milo"'
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110625- (2024)
Summary: Endocrine glands secrete hormones into the circulation to target distant tissues and regulate their functions. The qualitative relationship between hormone-secreting organs and their target tissues is well established, but a quantitative app
Externí odkaz:
https://doaj.org/article/884e19eba5b0471aaaa2a3147f1588cb
Autor:
Tomer Milo, Lior Maimon, Ben Cohen, Dafna Haran, Dror Segman, Tamar Danon, Anat Bren, Avi Mayo, Gadi Cohen Rappaport, Melvin McInnis, Uri Alon
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109234- (2024)
Summary: Bipolar disorder (BD) is marked by fluctuating mood states over months to years, often with elevated cortisol levels. Elevated cortisol can also trigger mood episodes. Here, we combine longitudinal hair cortisol and mood measurements with ma
Externí odkaz:
https://doaj.org/article/022c25b72f154577b406b4ad8a1e0266
Autor:
Shimrit Mayer, Tomer Milo, Achinoam Isaacson, Coral Halperin, Shoval Miyara, Yaniv Stein, Chen Lior, Meirav Pevsner-Fischer, Eldad Tzahor, Avi Mayo, Uri Alon, Ruth Scherz-Shouval
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The tumor microenvironment (TME) is comprised of non-malignant cells that interact with each other and with cancer cells, critically impacting cancer biology. The TME is complex, and understanding it requires simplifying approaches. Here we
Externí odkaz:
https://doaj.org/article/02b3d0850720428989cf063f0ad2829d
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 12, p e1011645 (2023)
Major depressive disorder (MDD) is the most common psychiatric disorder. It has a complex and heterogeneous etiology. Most treatments take weeks to show effects and work well only for a fraction of the patients. Thus, new concepts are needed to under
Externí odkaz:
https://doaj.org/article/7251c3098ef74df08a0ee08a594f3d83
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108084- (2023)
Summary: Many autoimmune disorders exhibit flares in which symptoms erupt and then decline, as exemplified by multiple sclerosis (MS) in its relapsing-remitting form. Existing mathematical models of autoimmune flares often assume regular oscillations
Externí odkaz:
https://doaj.org/article/9a8732f11773403ca7d9ec51dc5705e3
Autor:
Yael Korem Kohanim, Tomer Milo, Moriya Raz, Omer Karin, Alon Bar, Avi Mayo, Netta Mendelson Cohen, Yoel Toledano, Uri Alon
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 8, Pp 1-15 (2022)
Abstract Thyroid disorders are common and often require lifelong hormone replacement. Treating thyroid disorders involves a fascinating and troublesome delay, in which it takes many weeks for serum thyroid‐stimulating hormone (TSH) concentration to
Externí odkaz:
https://doaj.org/article/36e4c4bacc704912bfdad8424c732e16
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 7, Pp 1-13 (2020)
Abstract Stress activates a complex network of hormones known as the hypothalamic–pituitary–adrenal (HPA) axis. The HPA axis is dysregulated in chronic stress and psychiatric disorders, but the origin of this dysregulation is unclear and cannot b
Externí odkaz:
https://doaj.org/article/3502ee70acb74ef3b0c4079206b75044
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101501- (2020)
Summary: Cortisol is a major human stress hormone, secreted within minutes of acute stress. Cortisol also has slower patterns of variation: a strong circadian rhythm and a seasonal rhythm. However, longitudinal cortisol dynamics in healthy individual
Externí odkaz:
https://doaj.org/article/6d4d65b3c9ce4b4784ae277c8531c9d7
Autor:
Lior Maimon, Tomer Milo, Dafna Haran, Ben Cohen, Tamar Danon, Anat Bren, Avi Mayo, Gadi Cohen Rappaport, Uri Alon
Background Bipolar disorder (BD) is characterized by episodes of manic, depressive and mixed mood states which have profound effects on the patient's quality of life. BD is diagnosed and followed up clinically using psychiatric assessment, with curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67fbf946a82869c1e2051fd5f61d1fb9
https://doi.org/10.21203/rs.3.rs-2484487/v1
https://doi.org/10.21203/rs.3.rs-2484487/v1
Autor:
Avichai Tendler, Avi Mayo, Yael Korem Kohanim, Alon Bar, Omer Karin, Netta Mendelsohn-Cohen, Tomer Milo, Lior Maimon, Amos Tanay, Moriya Raz, Uri Alon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We provide a dataset of millions of hormone tests from medical records that shows seasonality with a winter−spring peak in hormones for reproduction, growth, metabolism, and stress adaptation. Together with a long history of studies on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a51c595e65c138367a58e917710c2ac
https://pubmed.ncbi.nlm.nih.gov/33531344
https://pubmed.ncbi.nlm.nih.gov/33531344