Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tomer, Babu"'
Autor:
Tomer Babu, Hiba Ghareeb, Uttara Basu, Hemma Schueffl, Sarah Theiner, Petra Heffeter, Gunda Koellensperger, Norman Metanis, Valentina Gandin, Ingo Ott, Claudia Schmidt, Dan Gibson
Publikováno v:
Angewandte Chemie. 135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805c9e38e533165ab2b182cc99d5dcc9
https://doi.org/10.1002/ange.202217233
https://doi.org/10.1002/ange.202217233
Autor:
Ingo Ott, Valentina Gandin, Claudia Schmidt, Annika Timm, Viktor Brabec, Uttara Basu, Hana Kostrhunova, Dan Gibson, Tomer Babu
Publikováno v:
Journal of Medicinal Chemistry. 64:11364-11378
"Multi-action" Pt(IV) derivatives of cisplatin with combretastatin A4 (CA4) bioactive ligands that are conjugated to Pt(IV) by carbonate are unique because the ligand (IC50 < 10 nM) is dramatically 1000-folds more cytotoxic than cisplatin in vitro. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a36b6b434ae105733f5a0b2986452a0
https://doi.org/10.1021/acs.jmedchem.1c00706
https://doi.org/10.1021/acs.jmedchem.1c00706
Publikováno v:
Inorganic Chemistry. 59:5182-5193
Multiaction Pt(IV) prodrugs can overcome resistance associated with the FDA approved Pt(II) drugs like cisplatin. Intracellular reduction of the octahedral Pt(IV) derivatives of cisplatin releases cisplatin and the two axial ligands. When the release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fbabb61d8e913986301e052fd0a7f9
https://doi.org/10.1021/acs.inorgchem.0c00445
https://doi.org/10.1021/acs.inorgchem.0c00445
Publikováno v:
Synthetic Communications. 50:438-445
The 2,3,4,5-tetrahydro-1H-benzo[2,3]benzofuro[6,5-b]azepine skeleton was built starting from dibenzofuran via 3-aminodibenzofuran, creating the 5-methylene-substituted azepine ring by an intramolec...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cab6ebca10ea0588d86079df781e7dc0
https://doi.org/10.1080/00397911.2019.1703001
https://doi.org/10.1080/00397911.2019.1703001
Autor:
Thirumal, Yempala, Tomer, Babu, Subhendu, Karmakar, Alina, Nemirovski, Maisaloon, Ishan, Valentina, Gandin, Dan, Gibson
Publikováno v:
Angewandte Chemie (International ed. in English). 58(50)
Most multi-action Pt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::566577ec57cacdfe9c6a8d4a1c59c87f
https://pubmed.ncbi.nlm.nih.gov/31599054
https://pubmed.ncbi.nlm.nih.gov/31599054