Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tomaz Budefeld"'
Autor:
Larisa Goričan, Tomaž Büdefeld, Helena Čelešnik, Matija Švagan, Boštjan Lanišnik, Uroš Potočnik
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 6, Pp 4632-4646 (2023)
Epigenetic studies on the role of DNA-modifying enzymes in HNSCC tumorigenesis have focused on a single enzyme or a group of enzymes. To acquire a more comprehensive insight into the expression profile of methyltransferases and demethylases, in the p
Externí odkaz:
https://doaj.org/article/1fcb549ecc914b4db9f2893be45dc050
Autor:
Živa Ledinek, Monika Sobočan, Damjan Sisinger, Marko Hojnik, Tomaž Büdefeld, Uroš Potočnik, Jure Knez
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Endometrial cancer is the most common gynecologic malignancy in the developed world. Risk stratification and treatment approaches are changing due to better understanding of tumor biology. Upregulated Wnt signaling plays an important role in cancer i
Externí odkaz:
https://doaj.org/article/fa60fda95c914cfab0366d15d6bab815
Autor:
Maša Sinreih, Rebeka Jójárt, Zoltán Kele, Tomaž Büdefeld, Gábor Paragi, Erzsébet Mernyák, Tea Lanišnik Rižner
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1499-1507 (2021)
Enzymes AKR1C regulate the action of oestrogens, androgens, and progesterone at the pre-receptor level and are also associated with chemo-resistance. The activities of these oestrone halides were investigated on recombinant AKR1C enzymes. The oestron
Externí odkaz:
https://doaj.org/article/85552082a3ce4fee999b489015b2a35d
Autor:
Matthew S Stratton, Michelle Staros, Tomaz Budefeld, Brian T Searcy, Connor Nash, Chad Eitel, David Carbone, Robert J Handa, Gregor Majdic, Stuart A Tobet
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e106015 (2014)
Neurons of the paraventricular nucleus of the hypothalamus (PVN) regulate the hypothalamic- pituitary-adrenal (HPA) axis and the autonomic nervous system. Females lacking functional GABA(B) receptors because of a genetic disruption of the R1 subunit
Externí odkaz:
https://doaj.org/article/bad640f52130422aac37d9f8199260fc
Autor:
Rok Kosir, Peter Juvan, Martina Perse, Tomaz Budefeld, Gregor Majdic, Martina Fink, Paolo Sassone-Corsi, Damjana Rozman
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31798 (2012)
The essential role of the Crem gene in normal sperm development is widely accepted and is confirmed by azoospermia in male mice lacking the Crem gene. The exact number of genes affected by Crem absence is not known, however a large difference has bee
Externí odkaz:
https://doaj.org/article/89148740dcc64f4a9d9a237ce3b7aefa
Publikováno v:
Endometrial cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bd2763c6a3580811d1d5ac17a4cc131
https://doi.org/10.1136/ijgc-2022-esgo.307
https://doi.org/10.1136/ijgc-2022-esgo.307
Autor:
Jakob Kljun, Renata Pavlič, Eva Hafner, Tanja Lipec, Sara Moreno-Da Silva, Primož Tič, Iztok Turel, Tomaž Büdefeld, Jure Stojan, Tea Lanišnik Rižner
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
In this study, we present the synthesis, kinetic studies of inhibitory activity toward aldo-keto reductase 1C (AKR1C) enzymes, and anticancer potential toward chemoresistant ovarian cancer of 10 organoruthenium compounds bearing diketonate (1–6) an
Externí odkaz:
https://doaj.org/article/f20c38b2a3054eb28ff3e7533d899f2f