Identifying genetic variants that affect viability in large cohorts.

Autor: Hakhamanesh Mostafavi, Tomaz Berisa, Felix R Day, John R B Perry, Molly Przeworski, Joseph K Pickrell

Publikováno v: PLoS Biology, Vol 15, Iss 9, p e2002458 (2017)

A number of open questions in human evolutionary genetics would become tractable if we were able to directly measure evolutionary fitness. As a step towards this goal, we developed a method to examine whether individual genetic variants, or sets of g

Externí odkaz: https://doaj.org/article/1058f9c026d74d709d5d086803e46b72

Additional file 2 of Comparing low-pass sequencing and genotyping for trait mapping in pharmacogenetics

Autor: Wasik, Kaja, Tomaz Berisa, Pickrell, Joseph K., Li, Jeremiah H., Fraser, Dana J., King, Karen, Cox, Charles

Additional file 2: Supplementary materials. Description of imputation performance using the HRC as a haplotype reference panel rather than the 1000 Genomes Phase 3 release. Figure S1. Comparison of imputation r2 across allele frequency bins for the 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac33147ae4c5fdebe31abeea4cdf0c61

Relative matching using low coverage sequencing

Autor: Daphna Weissglas-Volkov, Regev Schweiger, Joseph K. Pickrell, Jeremiah H. Li, Ella Petter, Tal Shor, Lior Almog, Tomaz Berisa, Yoav Naveh, Bar Shahino, Malka Aker, Yaniv Erlich, Shai Carmi, Oron Navon

Finding familial relatives using DNA has multiple applications, in genetic genealogy, population genetics, and forensics. So far, most relative matching algorithms rely on detecting identity-by-descent (IBD) segments with high quality genotype data.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17e910b15b95823e68bada7c8e641db5
https://doi.org/10.1101/2020.09.09.289322

Real-time PON signaling for emerging low-latency applications

Autor: Martin Maier, Kerim Fouli, Tomaz Berisa

Publikováno v: Computer Communications. 52:102-109

In this paper, we provide a comprehensive discussion focused on the motivation and benefits of providing real-time (RT) signaling mechanisms in multi-channel PONs, outlining several emerging low-latency applications such as Smart Grid, machine-to-mac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd79a887f244f2a2558be4b2d0ce2577
https://doi.org/10.1016/j.comcom.2014.06.008

Detection and interpretation of shared genetic influences on 42 human traits

Autor: David A. Hinds, Laure Ségurel, Joyce Y. Tung, Joseph K. Pickrell, Jimmy Z. Liu, Tomaz Berisa

Publikováno v: Nature Genetics
Nature Genetics, Nature Publishing Group, 2016, 48 (7), pp.709-717. ⟨10.1038/ng.3570⟩
Nature Genetics, 2016, 48 (7), pp.709-717. ⟨10.1038/ng.3570⟩

We performed a scan for genetic variants associated with multiple phenotypes by comparing large genome-wide association studies (GWAS) of 42 traits or diseases. We identified 341 loci (at a false discovery rate of 10%) associated with multiple traits

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d66696ec7789df26e3a1a344e30fd10
https://hal.archives-ouvertes.fr/hal-02122294/file/nihms-780506.pdf