Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tomasz Wegierski"'
Autor:
Sofiia Baranykova, Rishikesh Kumar Gupta, Arkadiusz Kajdasz, Iga Wasilewska, Matylda Macias, Aleksandra Szybinska, Tomasz Węgierski, Karim Abu Nahia, Shamba S. Mondal, Cecilia L. Winata, Jacek Kuźnicki, Lukasz Majewski
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Calcium is involved in vision processes in the retina and implicated in various pathologies, including glaucoma. Rod cells rely on store-operated calcium entry (SOCE) to safeguard against the prolonged lowering of intracellular calcium ion c
Externí odkaz:
https://doaj.org/article/ef3c06b4afc24f27a586cb85f8a34536
Autor:
Jacek Kuznicki, Tomasz Wegierski
Publikováno v:
Cell Calcium. 74:102-111
Store-operated calcium entry (SOCE) is the flow of calcium ions (Ca2+) into cells in response to the depletion of intracellular Ca2+ stores that reside predominantly in the endoplasmic reticulum (ER). The role of SOCE has been relatively well underst
Publikováno v:
Biochemical and Biophysical Research Communications. 478(3):1087-1092
Familial Alzheimer's disease (FAD)-causing mutations in presenilins were shown to alter intracellular calcium dynamics, including store-operated calcium entry (SOCE). However, the involvement of FAD-linked amyloid precursor protein (APP) in SOCE rema
Autor:
Tomasz Wegierski, Marta B. Wisniewska, Luis Puelles, Jacek Kuznicki, Andrzej Nagalski, Michal Dabrowski
Publikováno v:
Brain Structure & Function
Thalamocortical loops have been implicated in the control of higher-order cognitive functions, but advances in our understanding of the molecular underpinnings of neocortical organization have not been accompanied by similar analyses in the thalamus.
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Familial Alzheimer’s disease (AD) is caused by mutations in the genes that encode amyloid precursor protein (APP) and presenilins. Disturbances in calcium homeostasis have been observed in various cellular and animal models of AD and are proposed t
Autor:
Christoph Kopp, E. Wolfgang Kuehn, Daniel Steffl, Robert Tauber, Gerd Walz, Tomasz Wegierski, Michael Köttgen, Roland Nitschke, Björn Buchholz
Publikováno v:
The EMBO Journal. 28:490-499
Ca(2+) is an important signalling molecule that regulates multiple cellular processes, including apoptosis. Although Ca(2+) influx through transient receptor potential (TRP) channels in the plasma membrane is known to trigger cell death, the function
Autor:
Tomasz Wegierski, Xiao Fu, Albrecht Kramer-Zucker, Yan Wang, Gerd Walz, Stephanie Gaiser, Michael Köttgen
Publikováno v:
Journal of Biological Chemistry. 282:36561-36570
Transient receptor potential (TRP) proteins constitute a family of cation-permeable channels that are formed by homo- or heteromeric assembly of four subunits. Despite recent progress in the identification of protein domains required for the formatio
Publikováno v:
RNA. 7:1254-1267
Maturation of 18S rRNA and biogenesis of the 40S ribosomes in yeast requires a large number of trans-acting factors, including the U3 small nucleolar ribonucleoprotein (U3 snoRNP), and the recently characterized cyclase-like protein Rcl1p. U3 snoRNP
Publikováno v:
The EMBO Journal. 19:2115-2126
RNA 3'-terminal phosphate cyclases are evolutionarily conserved enzymes catalysing conversion of the 3'-terminal phosphate in RNA to the 2',3'-cyclic phosphodiester. Their biological role remains unknown. The yeast Saccharomyces cerevisiae contains a
Autor:
Urs Lewandrowski, Hongquan Peng, Tomasz Wegierski, Albert Sickmann, Gerd Walz, Barbara Müller
Publikováno v:
Biochemical and biophysical research communications. 391(4)
Transient Receptor Potential (TRP) proteins are non-selective cation channels performing diverse cellular functions. TRPV1 and TRPV4, two calcium-permeable channels of the vanilloid subfamily of TRP proteins, are activated by various physical and che