Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Tomasz Szkudelski"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 431 (2023)
Baicalin is a biologically active flavonoid compound that benefits the organism in various pathological conditions. Rodent studies have shown that this compound effectively alleviates diabetes-related disturbances in models of type 1 and type 2 diabe
Externí odkaz:
https://doaj.org/article/33bdaeeefe1e4b30be5d85714e4bba3b
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 150, Iss , Pp 112946- (2022)
Betaine (N, N, N-trimethylglycine) is an amino-acid derivative exerting numerous beneficial effects on the organism. This compound is found in human and animal diets but is also endogenously generated. However, its synthesis may be insufficient to ma
Externí odkaz:
https://doaj.org/article/2251800019614172b40309a48106d062
Publikováno v:
PeerJ, Vol 9, p e12092 (2021)
Hemin is an activator of heme oxygenase-1 (HO-1), an enzyme catalyzing heme degradation. Up-regulation of HO-1 is observed in response to various pathological conditions. Moreover, pharmacological activation of HO-1 is associated with numerous benefi
Externí odkaz:
https://doaj.org/article/36e5f738ad044e28ac4d7363490fcdbf
Publikováno v:
Molecules, Vol 27, Iss 16, p 5250 (2022)
Metformin is a biguanide compound commonly applied in humans with type 2 diabetes. The drug affects different tissues, including fat tissue. The direct influence of metformin on cells of fat tissue, i.e., adipocytes, is poorly elucidated. In the pres
Externí odkaz:
https://doaj.org/article/680eed47f1a542d1a4f46357a4b9b9a1
Publikováno v:
Molecules, Vol 27, Iss 17, p 5568 (2022)
Oxidative stress and inflammation play a crucial role in the pathogenesis and progression of diabetes. Currently, there is a growing need to exploit plant-derived bioactive compounds to support conventional therapies. The purpose of this study was to
Externí odkaz:
https://doaj.org/article/3850020454ed42f8a0943a65356eb196
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 125, Iss , Pp 110026- (2020)
Type 2 diabetes is associated with inflammatory and oxidative stress. Resveratrol, a naturally occurring diphenolic compound, was shown to improve glycemic control and alleviate metabolic disturbances in Goto-Kakizaki (GK) rats, a non-obese model of
Externí odkaz:
https://doaj.org/article/72ad81a38f8441eaa0396a78e1354099
Publikováno v:
Toxins, Vol 14, Iss 1, p 3 (2021)
Allyl isothiocyanate (AITC), a constituent of Brassica family plants, has been reported to possess a high bioactivity in animal and human cells, showing ambiguous properties from adverse to beneficial ones. It was reported its genotoxic, carcinogenic
Externí odkaz:
https://doaj.org/article/27ef004db2014025abd97aad894f6640
Autor:
Katarzyna Szkudelska, Marzanna Deniziak, Maciej Sassek, Ignacy Szkudelski, Wojciech Noskowiak, Tomasz Szkudelski
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2469 (2021)
Resveratrol is a biologically active diphenolic compound exerting multiple beneficial effects in the organism, including anti-diabetic properties. This action is, however, not fully elucidated. In the present study, we examined effects of resveratrol
Externí odkaz:
https://doaj.org/article/66f19a7c56bb4266a02369b079616f76
Autor:
Katarzyna Szkudelska, Marzanna Deniziak, Iwona Hertig, Tatiana Wojciechowicz, Marianna Tyczewska, Magdalena Jaroszewska, Tomasz Szkudelski
Publikováno v:
Nutrients, Vol 11, Iss 10, p 2488 (2019)
Resveratrol exhibits a pleiotropic, favorable action under various pathological conditions, including type 2 diabetes. However, its anti-diabetic effects in animal models and human trials have not been fully elucidated. The aim of the present study w
Externí odkaz:
https://doaj.org/article/b05de951b95445b697021668c70ddccf
Autor:
Ole Vang, Nihal Ahmad, Clifton A Baile, Joseph A Baur, Karen Brown, Anna Csiszar, Dipak K Das, Dominique Delmas, Carmem Gottfried, Hung-Yun Lin, Qing-Yong Ma, Partha Mukhopadhyay, Namasivayam Nalini, John M Pezzuto, Tristan Richard, Yogeshwer Shukla, Young-Joon Surh, Thomas Szekeres, Tomasz Szkudelski, Thomas Walle, Joseph M Wu
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e19881 (2011)
BackgroundResveratrol is a natural compound suggested to have beneficial health effects. However, people are consuming resveratrol for this reason without having the adequate scientific evidence for its effects in humans. Therefore, scientific valid
Externí odkaz:
https://doaj.org/article/304fb5edd52c42c799f803f46c240e79